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4-Bromo-2-fluoro-5-nitrophenol

4-Bromo-2-fluoro-5-nitrophenol Structure
4-Bromo-2-fluoro-5-nitrophenol structure
CAS No.
661463-12-3
Chemical Name:
4-Bromo-2-fluoro-5-nitrophenol
Synonyms
4-Bromo-2-fluoro-5-nitrophenol;Phenol, 4-bromo-2-fluoro-5-nitro-
CBNumber:
CB22455868
Molecular Formula:
C6H3BrFNO3
Molecular Weight:
236
MDL Number:
MFCD11100973
MOL File:
661463-12-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:34
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4-Bromo-2-fluoro-5-nitrophenol Properties

Boiling point 264.8±40.0 °C(Predicted)
Density 1.965±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka 6.27±0.24(Predicted)
Appearance Light brown to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)Environment (GHS09)
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H302-H315-H317-H318-H410
Precautionary statements  P261-P264-P270-P272-P273-P280-P301+P312+P330-P302+P352-P305+P351+P338+P310-P333+P313-P391-P501
HS Code  2908190090

4-Bromo-2-fluoro-5-nitrophenol price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC500262 4-Bromo-2-fluoro-5-nitrophenol 95% 661463-12-3 250mg $29 2026-06-04 Buy
Apolloscientific PC500262 4-Bromo-2-fluoro-5-nitrophenol 95% 661463-12-3 1g $69 2026-06-04 Buy
Apolloscientific PC500262 4-Bromo-2-fluoro-5-nitrophenol 95% 661463-12-3 5g $166 2026-06-04 Buy
Matrix Scientific 131691 4-Bromo-2-fluoro-5-nitrophenol 661463-12-3 250.00mg $27 2026-05-18 Buy
Matrix Scientific 131691 4-Bromo-2-fluoro-5-nitrophenol 661463-12-3 1.00g $61 2026-05-18 Buy
Product number Packaging Price Buy
PC500262 250mg $29 Buy
PC500262 1g $69 Buy
PC500262 5g $166 Buy
131691 250.00mg $27 Buy
131691 1.00g $61 Buy

4-Bromo-2-fluoro-5-nitrophenol Chemical Properties, Uses, Production

Synthesis

Carbonic acid, 4-bromo-2-fluoro-5-nitrophenyl ethyl ester

661463-11-2

4-BROMO-2-FLUORO-5-NITROPHENOL

661463-12-3

4-Bromo-2-fluoro-5-nitrophenyl ethyl carbonate (35 g, 113 mmol) was dissolved in methanol (200 mL) and sodium bicarbonate (19 g, 227 mmol) was added. The reaction mixture was stirred at 60 °C for 4 hours. After completion of the reaction, methanol was removed by distillation under reduced pressure. To the residue, water (55 mL) was added and the pH of the aqueous layer was adjusted to 5 with 6N hydrochloric acid solution.The aqueous layer was extracted twice with ethyl acetate, the organic layers were combined and dried with magnesium sulfate. The organic layer was concentrated under reduced pressure to give the target product 4-bromo-2-fluoro-5-nitrophenol (25 g, 93% yield) as a yellow solid.LC-MS (ES) (M + H)+ m/z = 237.

References

[1] Patent: WO2004/14361, 2004, A1. Location in patent: Page/Page column 39
[2] Patent: WO2006/2047, 2006, A2. Location in patent: Page/Page column 79

4-Bromo-2-fluoro-5-nitrophenol Preparation Products And Raw materials

Raw materials

Carbonic acid, 4-bromo-2-fluoro-5-nitrophenyl ethyl ester Hydrochloric acid

Preparation Products

4-Bromo-2-fluoro-5-nitrophenol Suppliers

Global Suppliers ( 51)
Supplier Tel Email Country ProdList Advantage
Beijing Eternalchem Co,. Ltd. 010-59484199 18611897322;18611897322; sales@eternalchem.com China 1993 60
Beijing Yisiyan Technology Research Center 010-56645598 13366904824; bjkaida@163.com China 1597 59
Shanghai Witofly Chemical Co.,Ltd sales@witofly.com China 2853 52
Mashilabs (Shanghai) Co.,Ltd. 19916721580 mafarm@126.com China 4534 58
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9781 50
SuZhou ShiYa Biopharmaceuticals, Inc. 0512-0512-52358471 17715136450 sales@shiyabiopharm.com China 9814 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Hangzhou Molcore Biopharmatech Co.,Ltd 400-711-5280 86-571-81025280 sales@molcore.com China 9957 58
Sichuan BoYou Biotechnology Co., Ltd. 028-65791793 18140026355 568470422@qq.com China 9961 58
Aikon International Limited 025-58851090 13913916777 sales01@aikonchem.com China 15947 58
Supplier Advantage
Beijing Eternalchem Co,. Ltd. 60
Beijing Yisiyan Technology Research Center 59
Shanghai Witofly Chemical Co.,Ltd 52
Mashilabs (Shanghai) Co.,Ltd. 58
Shanghai HuanChuan Industry Co.,Ltd. 50
SuZhou ShiYa Biopharmaceuticals, Inc. 58
Amadis Chemical Company Limited 58
Hangzhou Molcore Biopharmatech Co.,Ltd 58
Sichuan BoYou Biotechnology Co., Ltd. 58
Aikon International Limited 58

4-Bromo-2-fluoro-5-nitrophenol Spectrum

4-BROMO-2-FLUORO-5-NITROPHENOL(661463-12-3)1HNMR

661463-12-3 (4-Bromo-2-fluoro-5-nitrophenol) Related Search:

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Phenol, 4-bromo-2-fluoro-5-nitro- 4-Bromo-2-fluoro-5-nitrophenol 661463-12-3