Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester
![Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester Structure](CAS2/GIF/1147422-00-1.gif)
- CAS No.
- 1147422-00-1
- Chemical Name:
- Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester
- Synonyms
- 1-Boc-1H-octahydropyrrolo[3,2-c]pyridine;Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester;tert-butyl 2,3,3a,4,5,6,7,7a-octahydropyrrolo[3,2-c]pyridine-1-carboxylate;1H-Pyrrolo[3,2-c]pyridine-1-carboxylic acid, octahydro-, 1,1-diMethylethyl ester;tert-butyl octahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate, Mixture of diastereomers
- CBNumber:
- CB22491675
- Molecular Formula:
- C12H22N2O2
- Molecular Weight:
- 226.32
- MDL Number:
- MFCD11877862
- MOL File:
- 1147422-00-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 264543 | 1-Boc-1H-octahydropyrrolo[3,2-c]pyridine Asreported | 1147422-00-1 | 50mg | $531 | 2026-06-03 | Buy |
| Usbiological | 264543 | 1-Boc-1H-octahydropyrrolo[3,2-c]pyridine Asreported | 1147422-00-1 | 100mg | $744 | 2026-06-03 | Buy |
| Usbiological | 264543 | 1-Boc-1H-octahydropyrrolo[3,2-c]pyridine Asreported | 1147422-00-1 | 250mg | $1097 | 2026-06-03 | Buy |
| Usbiological | 264543 | 1-Boc-1H-octahydropyrrolo[3,2-c]pyridine Asreported | 1147422-00-1 | 500mg | $1735 | 2026-06-03 | Buy |
| Usbiological | 264543 | 1-Boc-1H-octahydropyrrolo[3,2-c]pyridine Asreported | 1147422-00-1 | 1g | $2229 | 2026-06-03 | Buy |
Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester Chemical Properties, Uses, Production
Synthesis
![1-Boc-1H-pyrrolo[3,2-c]pyridine](/CAS/GIF/148760-75-2.gif)
148760-75-2
![Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester](/CAS2/GIF/1147422-00-1.gif)
1147422-00-1
The general procedure for the synthesis of 1-Boc-1H-octahydropyrrolo[3,2-c]pyridine from 1-Boc-1H-pyrrolo[3,2-c]pyridine was as follows: 1H-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester (2.55 g) was dissolved in a mixed solvent of ethylene glycol monomethyl ether (40 mL) and acetic acid (1 mL), and catalytic amounts of palladium hydroxide/ carbon (Pd(OH)2/C). The reaction suspension was heated at 70 °C for 24 h under hydrogen (2.0 MPa) atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under vacuum to remove the solvent. The resulting residue was purified by silica gel column chromatography with the eluent being a solvent mixture of dichloromethane and methanol (10:1, v/v) to afford the final target product 1-Boc-1H-octahydropyrrolo[3,2-c]pyridine as a viscous liquid (2.64 g, 100.00% yield).
References
[1] Patent: WO2013/71697, 2013, A1. Location in patent: Paragraph 00276
[2] Patent: US2014/228361, 2014, A1. Location in patent: Paragraph 0418-0419
Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3833 | 58 |
| Shanghai civi chemical technology co.,Ltd | 86-21-34053660 | sale@labgogo.com | China | 9853 | 52 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3989 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3539 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Jiaxing Novartis Chemical Co., Ltd. | 18957373295 | China | 1579 | 58 | |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
View Latest Price from Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester pictures](/ProductImageEN2/2026-03/Small/8c3ebceb-61d6-4615-b0bf-400c36945e1c.gif) |
2026-03-11 | Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester
1147422-00-1
|
1kg | 97% | 1000kg | Henan Aochuang Chemical Co.,Ltd. | ||
![Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/02eaa64a-4d3f-473c-aa7a-a2de084b8a34.png) |
2020-01-10 | Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester
1147422-00-1
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester
1147422-00-1
- 97%
- Henan Aochuang Chemical Co.,Ltd.
-
- Octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester
1147422-00-1
- $1.00
- 99%
- Career Henan Chemical Co
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