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3-(Boc-amino)-2-piperidone

3-(Boc-amino)-2-piperidone Structure
3-(Boc-amino)-2-piperidone structure
CAS No.
99780-98-0
Chemical Name:
3-(Boc-amino)-2-piperidone
Synonyms
3-Boc-aMino-2-piperidinone;3-(Boc-amino)-2-piperidone;_x000D_3-(Boc-amino)-2-piperidone;tert-Butyl (2-oxopiperidin-3-yl)carbaMate;tert-butyl N-(2-oxopiperidin-3-yl)carbamate;(+/-)-3-<(tert-butoxycarbonyl)amino>-2-piperidone;1,1-Dimethylethyl?N-(2-oxo-3-piperidinyl)carbamate;Carbamic acid, N-(2-oxo-3-piperidinyl)-, 1,1-dimethylethyl ester
CBNumber:
CB22500771
Molecular Formula:
C10H18N2O3
Molecular Weight:
214.26
MDL Number:
MFCD13190662
MOL File:
99780-98-0.mol
MSDS File:
SDS
Last updated:2026-05-28 00:03:47
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3-(Boc-amino)-2-piperidone Properties

Boiling point 405.6±34.0 °C(Predicted)
Density 1.11±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 11.05±0.20(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319-H315-H335-H302
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501

3-(Boc-amino)-2-piperidone price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth ZDA78098 tert-Butyl (2-oxopiperidin-3-yl)carbamate 99780-98-0 5g $413 2026-06-05 Buy
Matrix Scientific 300209 tert-Butyl (2-oxopiperidin-3-yl)carbamate 99780-98-0 1.00g $62 2026-05-19 Buy
Matrix Scientific 300209 tert-Butyl (2-oxopiperidin-3-yl)carbamate 99780-98-0 5.00g $148 2026-05-19 Buy
Matrix Scientific 300209 tert-Butyl (2-oxopiperidin-3-yl)carbamate 99780-98-0 25.00g $742 2026-05-19 Buy
Synthonix B53251 tert-Butyl (2-oxopiperidin-3-yl)carbamate 97% 99780-98-0 250mg $55 2026-05-06 Buy
Product number Packaging Price Buy
ZDA78098 5g $413 Buy
300209 1.00g $62 Buy
300209 5.00g $148 Buy
300209 25.00g $742 Buy
B53251 250mg $55 Buy

3-(Boc-amino)-2-piperidone Chemical Properties, Uses, Production

Synthesis

3-amino-2-Piperidinone

1892-22-4

Di-tert-butyl dicarbonate

24424-99-5

3-(Boc-amino)-2-piperidone

99780-98-0

General procedure for the synthesis of 3-(Boc-amino)-2-piperidinone from 3-aminopiperidin-2-one and di-tert-butyl dicarbonate: To a 500 mL round-bottomed flask were added 3-aminopiperidin-2-one (10 g, 87.61 mmol, 1.00 equiv), methanol (200 g, 6.24 mol, 71.25 equiv), and triethylamine (20 mL). A solution of di-tert-butyl dicarbonate (20 g, 91.64 mmol, 1.05 equiv) in methanol (100 mL) was added slowly and dropwise with stirring at 0 °C. The reaction mixture was stirred at room temperature overnight. After completion of the reaction, the mixture was concentrated under vacuum. The crude product was purified by column chromatography to afford 16 g (85% yield) of 3-(Boc-amino)-2-piperidone as a white solid.

References

[1] Patent: WO2017/75056, 2017, A1. Location in patent: Paragraph 0410
[2] Journal of Medicinal Chemistry, 1986, vol. 29, # 2, p. 251 - 260
[3] Farmaco, 2004, vol. 59, # 4, p. 271 - 277
[4] Patent: WO2004/98589, 2004, A1. Location in patent: Page 163

3-(Boc-amino)-2-piperidone Preparation Products And Raw materials

Raw materials

Boc-Orn-OH 3-amino-2-Piperidinone Di-tert-butyl dicarbonate 3-Amino-2-piperidinone hydrochloride (R)-3-Aminopiperidine-2-one
Methanol Triethylamine

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Preparation Products

3-AMino-1-Methylpiperidin-2-one

3-(Boc-amino)-2-piperidone Suppliers

Global Suppliers ( 41)
Supplier Tel Email Country ProdList Advantage
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55
Hangzhou J&H Chemical Co., Ltd. 0571-87396432 sales@jhechem.com China 14905 59
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Accela ChemBio Inc. +1(858) 699-3322 marketing@accelachem.com United States 6022 65
Nanjing YaoCheng Pharmaceutical Co., Ltd. 025-57043319 15261831516 307514552@qq.com China 298 50
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai JingSi Biological Technology Co., Ltd 18221840760 2990760589@qq.com China 241 58
JiangYin Ruisheng Chemical Co., Ltd. 13003356808 1485751188@qq.com China 403 55
Amatek Scientific Co. Ltd. 0512-56316828 400-867-5858;400-867-5858 info@amateksci.com China 28760 58
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
Supplier Advantage
ShangHai AmK Pharmaceutical Technology Co., Ltd. 55
Hangzhou J&H Chemical Co., Ltd. 59
Cool Pharm, Ltd 58
Accela ChemBio Inc. 65
Nanjing YaoCheng Pharmaceutical Co., Ltd. 50
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai JingSi Biological Technology Co., Ltd 58
JiangYin Ruisheng Chemical Co., Ltd. 55
Amatek Scientific Co. Ltd. 58
Aikon International Limited 58

View Latest Price from 3-(Boc-amino)-2-piperidone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-(Boc-amino)-2-piperidone pictures 2020-01-08 3-(Boc-amino)-2-piperidone
99780-98-0
 1KG 98%; 99% 1kg; 10kg; 25kg Career Henan Chemical Co

3-(Boc-amino)-2-piperidone Spectrum

3-(Boc-amino)-2-piperidone(99780-98-0)1HNMR

99780-98-0 (3-(Boc-amino)-2-piperidone) Related Search:

3-amino-2-Piperidinone Carbamic acid, [(3R)-2-oxo-3-piperidinyl]-, 1,1-dimethylethyl ester (9CI) (S)-3-Boc-amino-2-piperidone 3-Amino-2-piperidinone hydrochloride 3-(R)-Amino-piperidin-2-one hydrochloride
(S)-3-aminopiperidin-2-one Hydrochloride

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3-(Boc-amino)-2-piperidone tert-Butyl (2-oxopiperidin-3-yl)carbaMate 3-Boc-aMino-2-piperidinone (+/-)-3-<(tert-butoxycarbonyl)amino>-2-piperidone tert-butyl N-(2-oxopiperidin-3-yl)carbamate Carbamic acid, N-(2-oxo-3-piperidinyl)-, 1,1-dimethylethyl ester _x000D_3-(Boc-amino)-2-piperidone 1,1-Dimethylethyl?N-(2-oxo-3-piperidinyl)carbamate 99780-98-0