3-Iodopyridine-2-carboxylic acid methyl ester
- CAS No.
- 73841-41-5
- Chemical Name:
- 3-Iodopyridine-2-carboxylic acid methyl ester
- Synonyms
- Methyl 3-iodopicolinate;Methyl 3-iodo-2-picolinate;Methyl 3-iodopyridine-2-carboxylate 97%;3-Iodo-2-pyridinecarboxylic acid methyl ester;3-Iodopyridine-2-carboxylic acid methyl ester;2-Pyridinecarboxylic acid, 3-iodo-, methyl ester
- CBNumber:
- CB22506652
- Molecular Formula:
- C7H6INO2
- Molecular Weight:
- 263.03
- MDL Number:
- MFCD01860192
- MOL File:
- 73841-41-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 298.5±20.0 °C(Predicted) |
|---|---|
| Density | 1.844±0.06 g/cm3(Predicted) |
| Flash point | >110℃ |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | solid |
| pka | -0.66±0.10(Predicted) |
| InChI | 1S/C7H6INO2/c1-11-7(10)6-5(8)3-2-4-9-6/h2-4H,1H3 |
| InChIKey | ITYQUGKRGXNQSC-UHFFFAOYSA-N |
| SMILES | COC(=O)c1ncccc1I |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P271-P260-P280 |
| WGK Germany | 3 |
| HS Code | 2933399990 |
| Storage Class | 11 - Combustible Solids |
3-Iodopyridine-2-carboxylic acid methyl ester price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 766844 | Methyl 3-iodopyridine-2-carboxylate 97% | 73841-41-5 | 1g | $113 | 2026-04-30 | Buy |
| Usbiological | 280992 | Methyl 3-iodopyridine-2-carboxylate Asreported | 73841-41-5 | 500mg | $382 | 2026-06-03 | Buy |
| Usbiological | 280992 | Methyl 3-iodopyridine-2-carboxylate Asreported | 73841-41-5 | 1g | $573 | 2026-06-03 | Buy |
| Usbiological | 280992 | Methyl 3-iodopyridine-2-carboxylate Asreported | 73841-41-5 | 2g | $878 | 2026-06-03 | Buy |
| Usbiological | 280992 | Methyl 3-iodopyridine-2-carboxylate Asreported | 73841-41-5 | 5g | $1204 | 2026-06-03 | Buy |
3-Iodopyridine-2-carboxylic acid methyl ester Chemical Properties, Uses, Production
Synthesis
67-56-1
73841-32-4
73841-41-5
General procedure for the synthesis of methyl 3-iodopyridinecarboxylate from methanol and 3-iodopyridine-2-carboxylic acid: a mixture of 3-iodopyridine-2-carboxylic acid (D1, 3.0 g, 0.012 mol) and concentrated sulfuric acid (2 mL) in methanol (100 mL) was heated and refluxed for 18 hr at 65 °C. After completion of the reaction, the solvent was removed by rotary evaporator under reduced pressure. The residue was alkalized to neutrality with solid sodium bicarbonate and subsequently extracted with ethyl acetate (3 × 100 mL). The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give methyl 3-iodopyridinecarboxylate (2.2 g, 70% yield). NMR hydrogen spectrum (CDCl3, 250 MHz) δH: 4.01 (3H, s), 7.13 (1H, dd), 8.29 (1H, dd), 8.64 (1H, dd). Mass spectrum (electrospray ionization): calculated value of 263 and measured value of 264 (MH+) for C7H6INO2.
References
[1] Patent: US2008/312209, 2008, A1. Location in patent: Page/Page column 13
[2] Patent: WO2007/7018, 2007, A1. Location in patent: Page/Page column 39
[3] Patent: WO2006/25783, 2006, A1. Location in patent: Page/Page column 120-121
3-Iodopyridine-2-carboxylic acid methyl ester Preparation Products And Raw materials
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