Sideroxylin
- CAS No.
- 3122-87-0
- Chemical Name:
- Sideroxylin
- Synonyms
- Sideroxylin;Sideroxyline;5,4'-dihydroxy-7-methoxy-6,8-dimethylflavone;4',5-Dihydroxy-7-methoxy-6,8-dimethylflavone;4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-6,8-dimethyl-
- CBNumber:
- CB22520010
- Molecular Formula:
- C18H16O5
- Molecular Weight:
- 312.32
- MDL Number:
- MFCD20260427
- MOL File:
- 3122-87-0.mol
- MSDS File:
- SDS
Sideroxylin Chemical Properties,Uses,Production
Uses
Sideroxylin is a C-methylated flavone isolated from Callistemon lanceolatus and exerts antimicrobial activity against Staphylococcus aureus. Sideroxylin inhibits ovarian cancer cell proliferation and induces apoptosis, causing DNA fragmentation, depolarization of the mitochondrial membrane, the generation of reactive oxygen species (ROS)[1].
Definition
ChEBI: Sideroxylin is a monomethoxyflavone that is flavone substituted by a methoxy group at position 7, hydroxy groups at positions 5 and 4' and methyl groups at positions 6 and 8. It has been isolated from Hydrastis canadensis and Eucalyptus species. It has a role as a plant metabolite. It is a dihydroxyflavone and a monomethoxyflavone. It is functionally related to a flavone.
target
Antifection
References
[1] Sunwoo Park, et al. Sideroxylin (Callistemon Lanceolatus) Suppressed Cell Proliferation and Increased Apoptosis in Ovarian Cancer Cells Accompanied by Mitochondrial Dysfunction, the Generation of Reactive Oxygen Species, and an Increase of Lipid Peroxidat DOI:10.1002/jcp.26540
Sideroxylin Preparation Products And Raw materials
Raw materials
Preparation Products
Sideroxylin Suppliers
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