Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>Artemether

Artemether

Artemether Structure
Artemether structure
CAS No.
71963-77-4
Chemical Name:
Artemether
Synonyms
ARTHEMETER;artMether;Artimether;ArteMether (SM-224);[3r-(3r,5as,6s,8as,9r,10r,12s,12ar**)]-decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12h-pyrano[4,3-j]-1,2-benzodioxepin;SM-224;Gvither;ArteMos;ArtenaM;Falcidol
CBNumber:
CB4248286
Molecular Formula:
C16H26O5
Molecular Weight:
298.37
MDL Number:
MFCD00866205
MOL File:
71963-77-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-17 09:03:53
Request For Quotation

Artemether Properties

Melting point 86-88°C
Boiling point 359.79°C (rough estimate)
alpha D19.5 +171° (c = 2.59 in CHCl3)
Density 1.0733 (rough estimate)
refractive index 1.6200 (estimate)
storage temp. room temp
solubility DMSO: ≥20mg/mL
form powder
color off-white to light brown
optical activity [α]/D +155 to +175°, c = 0.5 in methanol
Merck 14,815
InChI InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1
InChIKey SXYIRMFQILZOAM-HVNFFKDJSA-N
SMILES O1[C@]23[C@@]4([H])O[C@@](C)(CC[C@@]2([H])[C@H](C)CC[C@@]3([H])[C@@H](C)[C@@H](OC)O4)O1
FDA UNII C7D6T3H22J
ATC code P01BE02
UNSPSC Code 51101908
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Danger
Hazard statements  H242-H302
Precautionary statements  P210-P235-P280-P301+P312-P370+P378-P410
Hazard Codes  Xn
Risk Statements  22
Safety Statements  24/25
WGK Germany  3
RTECS  KD4165000
HS Code  29329930
Storage Class 5.2 - Organic peroxides and self-reacting hazardous materials
Hazard Classifications Acute Tox. 4 Oral
Org. Perox. D
Hazardous Substances Data 71963-77-4(Hazardous Substances Data)
Toxicity LD50 i.m. in mice: 263 mg/kg (China Cooperative Research Group on Qinghaosu)
NFPA 704
0
2 0

Artemether price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A9361 Artemether ≥98% (HPLC) 71963-77-4 5mg $100 2026-04-30 Buy
Sigma-Aldrich PHR3423 Artemether certified reference material, pharmaceutical secondary standard 71963-77-4 200MG $259 2026-04-30 Buy
Sigma-Aldrich 1042780 Artemether United States Pharmacopeia (USP) Reference Standard 71963-77-4 100mg $422 2026-04-30 Buy
TCI Chemical A2190 Artemether >98.0%(HPLC) 71963-77-4 5g $80 2026-04-30 Buy
TCI Chemical A2190 Artemether >98.0%(HPLC) 71963-77-4 25g $237 2026-04-30 Buy
Product number Packaging Price Buy
A9361 5mg $100 Buy
PHR3423 200MG $259 Buy
1042780 100mg $422 Buy
A2190 5g $80 Buy
A2190 25g $237 Buy

Artemether Chemical Properties, Uses, Production

Description

Artemether is an antiparasitic compound and a derivative of artemisinin . It induces mortality in adult wild-type and pfatp6-mutant P. falciparum but the efficacy is decreased in the mutants (IC50s = 8.2 and 13.5 nM, respectively). Artemether reduces parasitemia in P. falciparum-infected monkeys and P. berghei-infected mice with 50% curative dose (CD50) values of 7.1 and 55 mg/kg, respectively. It also reduces the worm burden of S. mansoni trematodes in mice when used at doses ranging from 200 to 500 mg/kg. Formulations containing artemether have been used in the treatment of malaria.

Chemical Properties

White Solid

Uses

Derivative of Artemisinin (A777500). Antimalarial, used to treat strains of malaria which are multi-drug resistant.

Uses

atypical antidepressant, norepinephrine and dopamine reuptake inhibitor, and nicotinic antagonist

Uses

Artemether and lumefantrine combination therapy is indicated for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum, including malaria acquired in chloroquine-resistant areas. May also be used to treat uncomplicated malaria when

Definition

ChEBI: An artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falcip rum malaria.

General Description

Artemisinin (ART) is a natural compound present in Artemisia annua, a traditional Chinese plant.

Biochem/physiol Actions

Artemether is a methyl ether derivative of artemisinin. It is used against multi-drug resistant strains of the malaria parasite, Plasmodium falciparum, and shows potential in treatment of schistosomiasis.

Safety Profile

Poison by intramuscular route.Experimental reproductive effects. When heated todecomposition it emits acrid smoke and irritating fumes.

target

Antifection

storage

Store at -20°C

References

[1] S H XIAO  B A C. In vitro and in vivo studies of the effect of artemether on Schistosoma mansoni.[J]. Antimicrobial Agents and Chemotherapy, 1989, 33 9: 1557-1562. DOI: 10.1128/aac.33.9.1557
[2] DYLAN R PILLAI. Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections.[J]. Malaria Journal, 2012: 131. DOI: 10.1186/1475-2875-11-131
[3] M J SHMUKLARSKY. Comparison of beta-artemether and beta-arteether against malaria parasites in vitro and in vivo.[J]. American Journal of Tropical Medicine and Hygiene, 1993, 48 3: 377-384. DOI: 10.4269/ajtmh.1993.48.377

Artemether synthesis

67-56-1
71939-50-9
71963-77-4
Synthesis of Artemether from Methanol and DHQHS 2

Artemether Preparation Products And Raw materials

Raw materials

Preparation Products

Artemisinin

Artemether Suppliers

Global Suppliers ( 679)
Supplier Tel Email Country ProdList Advantage
GUANGZHOU CHANGTHINKING IMP.&EXP.CO.,LTD 020-37651955 13682223272 173901442@qq.com China 689 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9409 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 45000 61
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16307 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Supplier Advantage
GUANGZHOU CHANGTHINKING IMP.&EXP.CO.,LTD 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Chembest Research Laboratories Limited 61
TCI (Shanghai) Development Co., Ltd. 81
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61
Pure Chemistry Scientific Inc. 62
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64

Related articles

View Latest Price from Artemether manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Artemether pictures 2026-10-21 Artemether
71963-77-4
 0.99 RongNa Biotechnology Co.,Ltd
Artemether pictures 2026-10-21 Artemether
71963-77-4
 $400.00-1000.00 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Artemether pictures 2026-10-21 Artemether
71963-77-4
 1kg 0.99 1000kg Shaanxi Xianhe Biotech Co., Ltd
  • Artemether pictures
  • Artemether
    71963-77-4
  • 0.99
  • RongNa Biotechnology Co.,Ltd
  • Artemether pictures
  • Artemether
    71963-77-4
  • $400.00-1000.00
  • 99%
  • HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
  • Artemether pictures
  • Artemether
    71963-77-4
  • $0.00
  • 0.99
  • Shaanxi Xianhe Biotech Co., Ltd

Artemether Spectrum

Artemether(71963-77-4)1HNMR

71963-77-4 (Artemether) Related Search:

4-Methoxybenzylchloride p-Anisidine Anisole 3-Methoxybenzaldehyde 4-Methoxyphenylacetone
p-Anisaldehyde 2-Methoxyethanol (Trifluoromethoxy)benzene 4-Methoxyphenylacetic acid Quercetin
tert-Amyl hydroperoxide Arteether ARTEMETHER tert-Butyl hydroperoxide alpha-Artemether
artemisitene ArteMether Tetrahydrofuran Acetate ALPHA-ARTEMETHER

1of4

methyl-dihydroartemisinine ARTEMETHER Artimether ArtemetherC16H26O5 cgp56696 dihydroartemisininmethylether dihydroquinghaosumethylether Artesaph Artesian Decahydro-10-Methoxy-3,6,9-triMethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin Falcidol Gvither Larither MalarteM ArteMether (SM-224) ARTEMTHER artMether Artemether [3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin Artemether 71963-77-4 ARTEMETHER PH. INT 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12aR)-, (+) (3R,5aα,8aα,12aR)-Decahydro-10β-methoxy-3,6α,9β-trimethyl-3,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin (3R,5aα,8aα,12aR)-Decahydro-10β-methoxy-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin Dihydroartemisin methyl ether SM-224 WR-254986 (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin dihydroqinghaosu methyl ether Artemether (100 mg) ArteMos ArtenaM 3,12-epoxy-12h-pyrano(4,3-j)-1,2-benzodioxepin,decahydro-10-methoxy-3,6,9-trim 5a-beta,6-beta,8a-beta,9-alpha,12-beta,12ar)-(3-alph(+)-ethyl artemisininelactolmethylether Artemether> 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)- (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Methoxy-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene Artemether CP2015 α-(N-Methyl-Benzylamino）-3-Hydroxyacetophenone Hydrochloride (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene Artemether USP/EP/BP Artemetherr ArtemetherQ: What is Artemether Q: What is the CAS Number of Artemether Q: What is the storage condition of Artemether Q: What are the applications of Artemether Artemether (1042780) 13C,2H3]-β-Artemether Artemether, ≥ 98.0% (+)-Artemether Artemether, 10 mM in DMSO Alpha-artemether RS Artemether RS (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane [3r-(3r,5as,6s,8as,9r,10r,12s,12ar**)]-decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12h-pyrano[4,3-j]-1,2-benzodioxepin ARTHEMETER Artemether (Standard) (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-Methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin 71963-77-4 963-77-4 C16H26O5