Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate
- CAS No.
- 1174046-84-4
- Chemical Name:
- Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate
- Synonyms
- Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3;ethyl 4-ethoxy-2-oxo-1H-pyridine-3-carboxylate;Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxyla;thyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate;Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate;3-Pyridinecarboxylic acid, 4-ethoxy-1,2-dihydro-2-oxo-, ethyl ester;Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate ISO 9001：2015 REACH
- CBNumber:
- CB22533933
- Molecular Formula:
- C10H13NO4
- Molecular Weight:
- 211.21
- MDL Number:
- MFCD18911742
- MOL File:
- 1174046-84-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | E52994 | Ethyl 4-ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate 95+% | 1174046-84-4 | 1g | $40 | 2026-05-06 | Buy |
| Synthonix | E52994 | Ethyl 4-ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate 95+% | 1174046-84-4 | 5g | $190 | 2026-05-06 | Buy |
| Synthonix | E52994 | Ethyl 4-ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate 95+% | 1174046-84-4 | 10g | $380 | 2026-05-06 | Buy |
| Synthonix | E52994 | Ethyl 4-ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate 95+% | 1174046-84-4 | 25g | $740 | 2026-05-06 | Buy |
| ACHEMBLOCK | S86447 | Ethyl 4-ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate 95% | 1174046-84-4 | 5G | $150 | 2026-05-27 | Buy |
Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate Chemical Properties, Uses, Production
Synthesis
1345855-03-9
1174046-84-4
General procedure for the synthesis of ethyl 2-oxo-4-ethoxy-1,2-dihydropyridine-3-carboxylate from ethyl 2-cyano-5-(dimethylamino)-3-ethoxypenta-2,4-dienoate: ethyl 2-cyano-5-(dimethylamino)-3-ethoxypenta-2,4-dienoate (15.0 g, 63 mmol) was mixed with acetic acid (600 mL) and reacted at reflux overnight. After completion of the reaction, the mixture was cooled to room temperature and concentrated under reduced pressure to remove the solvent. The residue was treated with water and washed with ethyl acetate (2×). The aqueous layer was adjusted to pH 9-10 with sodium bicarbonate and extracted with dichloromethane (3×). The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. Finally, it was purified by silica gel column chromatography to afford ethyl 2-oxo-4-ethoxy-1,2-dihydropyridine-3-carboxylate (9.0 g, 67% yield).
References
[1] Patent: WO2014/145004, 2014, A1. Location in patent: Paragraph 0103
[2] Patent: WO2011/139891, 2011, A1. Location in patent: Page/Page column 59
[3] Patent: WO2013/78295, 2013, A2. Location in patent: Paragraph 00184
Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 28-83379370 13880556291 | tcy@tcypharm.com | China | 509 | 57 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 | sales@sun-shinechem.com | China | 1197 | 64 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| Wulechem Co., Ltd. | 13761914825 | wulesian@wulechem.com | China | 285 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4534 | 58 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Shanghai Synteam Biochem CO.,ltd | +86-021-58380978 13482386415 | info@systeambc.com | China | 897 | 50 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Accela ChemBio Inc. | +1(858) 699-3322 | marketing@accelachem.com | United States | 6022 | 65 |
View Latest Price from Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate
1174046-84-4
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-01-08 | Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate
1174046-84-4
|
1KG | 98%; 99% | 1kg; 10kg; 25kg | Career Henan Chemical Co |
-
- Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate
1174046-84-4
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Ethyl 4-Ethoxy-2-oxo-1,2-dihydropyridine-3-carboxylate
1174046-84-4
- $0.01
- 98%; 99%
- Career Henan Chemical Co
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