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ChemicalBook >> CAS DataBase List >>(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester

(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester

(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Structure
(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester structure
CAS No.
629652-44-4
Chemical Name:
(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester
Synonyms
TDF-LB-M2;Tadalafil-004;Tadalafil-004-1R3S;Tadalafil Impurity 9;Tadalafil Impurity 67;Tildenafil Impurity 24;(1R,3S)-Chloropretadalafil;3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2;Tadalafil intermediate II diastereomer II;methyl (1R,3S)-1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indole-3-carboxylate
CBNumber:
CB22542863
Molecular Formula:
C22H19ClN2O5
Molecular Weight:
426.85
MDL Number:
MFCD27918682
MOL File:
629652-44-4.mol
MSDS File:
SDS
Last updated:2025-07-14 15:27:00
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(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Properties

Melting point 208 °C(Solv: ethyl ether (60-29-7))
Boiling point 627.5±55.0 °C(Predicted)
Density 1.445±0.06 g/cm3(Predicted)
storage temp. Room Temp
solubility DMSO, Methanol (Sparingly)
form Solid
pka 16.25±0.60(Predicted)
color Light Beige

(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-B200000-10MG (1R,3S)-Chloropretadalafil 629652-44-4 10mg $205 2026-06-03 Buy
TRC TRC-B200000-100MG (1R,3S)-Chloropretadalafil 629652-44-4 100mg $1611 2026-06-03 Buy
Usbiological 003275 (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester 629652-44-4 10mg $482 2026-06-03 Buy
Biosynth EAB65244 (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester 629652-44-4 5mg $250 2026-06-04 Buy
Biosynth EAB65244 (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester 629652-44-4 10mg $371.7 2026-06-04 Buy
Product number Packaging Price Buy
TRC-B200000-10MG 10mg $205 Buy
TRC-B200000-100MG 100mg $1611 Buy
003275 10mg $482 Buy
EAB65244 5mg $250 Buy
EAB65244 10mg $371.7 Buy

(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Chemical Properties, Uses, Production

Chemical Properties

Brown Solid

Uses

Tadalafil (T004500) derivative.

(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

cis-Tadalafil

(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Suppliers

Global Suppliers ( 52)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-83725681-603 China 4484 50
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 15250997978 1511893459@qq.com China 4777 55
Shanghai Xiang Xin Industrial Co., Ltd. 021-50211651 13651607026; sales@xxgmpharm.com China 499 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Sichuan jiayinglai technology CO.,LTD 9018 15982359653 1394531348@qq.com China 2271 55
Shandong Chengchuang Blue Sea Pharmaceutical Technology Co., Ltd. 0531-58897130 15508676053 drug_impurity@sdcclh.com China 2526 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50
S.Z. PhyStandard Bio-Tech. Co., Ltd. 50
Quality Control Solutions Ltd. 56
Nanjing XiZe Biotechnology CO., Ltd. 55
Shanghai Xiang Xin Industrial Co., Ltd. 58
Amadis Chemical Company Limited 58
Sichuan jiayinglai technology CO.,LTD 55
Shandong Chengchuang Blue Sea Pharmaceutical Technology Co., Ltd. 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58

(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Spectrum

(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester(629652-44-4)1HNMR

629652-44-4 ((1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester) Related Search:

Tadalafil EP Impurity Tadalafil impurity D(+)-Tryptophan ent-Tadalafil (1R,3R)-1-(benzo[d][1,3]dioxol-5-yl)-2-(2,2-dichloroacetyl) -2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate
JLEQLXGZAIAEFX-VRQJEYPFSA-N Nortadalafil (1R,3R)-1-(benzo[d][1,3]dioxol-5-yl)-2-(dimethylglycyl)-2,3,4,9-tetrahydro-1H-pyrido [3,4-b]indole-3-carboxylate methyl Tadalafil iMpurity D cis-Tadalafil
(1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester cis-ent-Tadalafil (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester
L-Tryptophan Tadalafil KetolactaM Benzhydryl 6,6-dihydropenicillic acid 1-oxide[tazobactam intermediate]

1of4

Tadalafil-004 Tadalafil Impurity 9 Tadalafil-004-1R3S 1H-Pyrido[3,4-b]indole-3-carboxylic acid,1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-, methylester, (1R,3S)- Tadalafil impurity 4/(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Tadalafil Impurity 67 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-, methyl ester, (1R,3S)- methyl (1R,3S)-1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H- pyrido[3,4-b]indole-3-carboxylate Tadalafil intermediate II diastereomer II TDF-LB-M2 (1R,3S)-methyl 1-(benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate? (Tadalafil Impurity） (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester (1R,3S)-Chloropretadalafil 3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2 Tildenafil Impurity 24 629652-44-4 Chiral Reagents Inhibitors Intermediates & Fine Chemicals Pharmaceuticals