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ChemicalBook >> CAS DataBase List >>2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride

2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride

2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride Structure
2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride structure
CAS No.
615571-23-8
Chemical Name:
2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride
Synonyms
SSR504734;SSR504734 HCl;Compound 1549;SSR 504734 hydrochloride;2-chloro-N-((S)-phenyl((S)-piperidin-2-yl)methyl)-3-(trifluoromethyl)benzamide hydrochloride;2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride
CBNumber:
CB22546487
Molecular Formula:
C20H20ClF3N2O.HCl
Molecular Weight:
433
MDL Number:
MFCD16628069
MOL File:
615571-23-8.mol
MSDS File:
SDS
Last updated:2026-07-16 07:06:08
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2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride Properties

storage temp. 4°C, away from moisture and light
form Solid
color White to off-white
FDA UNII L297UZF32G

2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth BS162755 SSR 504734 hydrochloride 615571-23-8 1mg $250 2026-06-04 Buy
Biosynth BS162755 SSR 504734 hydrochloride 615571-23-8 5mg $669.05 2026-06-04 Buy
Biosynth BS162755 SSR 504734 hydrochloride 615571-23-8 10mg $1070.5 2026-06-04 Buy
ChemScene CS-0002763 SSR504734 99.42% 615571-23-8 5mg $217 2026-06-04 Buy
ChemScene CS-0002763 SSR504734 99.42% 615571-23-8 10mg $347 2026-06-04 Buy
Product number Packaging Price Buy
BS162755 1mg $250 Buy
BS162755 5mg $669.05 Buy
BS162755 10mg $1070.5 Buy
CS-0002763 5mg $217 Buy
CS-0002763 10mg $347 Buy

2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride Chemical Properties, Uses, Production

Uses

SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 (IC50=18, 15, and 38nM, respectively). SSR504734 shows anti-schizophrenia, anti-anxiety and anti-depression activities[1].

in vivo

SSR504734 (i.p. and p.o.; 1-100 mg/kg; once) treatment shows good oral bioavailability[1].
SSR504734 (i.p.; 30 mg/kg; once) induces a rapid and significant decrease of specific glycine uptake[1].
SSR504734 (i.p.; 10 mg/kg; once) increases extracellular levels of Glycine in the prefrontal cortex (PFC) of freely moving rats[1].

Animal Model:Male Sprague-Dawley rats[1]
Dosage:1-100 mg/kg
Administration:Intraperitoneal injection and oral gavage.; 1-100 mg/kg; once
Result:Showed ID50 values of 5.0 and 4.6mg/kg for i.p. and p.o. treatments, respectively.
Animal Model:Male Sprague-Dawley rats[1]
Dosage:30 mg/kg
Administration:Intraperitoneal injection; 30 mg/kg; once
Result:Maintained at about 80% inhibition from 1 to 7h after administration.
Animal Model:Male Sprague-Dawley rats[1]
Dosage:10 mg/kg
Administration:Intraperitoneal injection; 10 mg/kg; once
Result:Produced a rapid and sustained increase in PFC extracellular levels of glycine.

IC 50

hGlyT1: 18 nM (IC50); rGlyT1: 15 nM (IC50)

References

[1] Ronan Depoortère, et al. Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic. Neuropsychopharmacology. 2005 Nov;30(11):1963-85. DOI:10.1038/sj.npp.1300772

2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride Suppliers

Global Suppliers ( 19)
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Amatek Scientific Co. Ltd. 0512-56316828 400-867-5858;400-867-5858 info@amateksci.com China 28760 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
CONIER CHEM AND PHARMA LIMITED sales@conier.com China 49906 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20027 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2934 58
Beijing Boorsen Biotechnology Co., Ltd 400-901-9800 18611424007 cis@bioss.com.cn China 9185 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 025-66061636 19370895928 qqyang@aikonchem.com China 9995 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
Amatek Scientific Co. Ltd. 58
TargetMol Chemicals Inc. 58
CONIER CHEM AND PHARMA LIMITED 58
TargetMol Chemicals Inc. 58
Suzhou Meishi Biotechnology Co., Ltd. 58
Shanghai Tachizaki Biomedical Research Center 58
Beijing Boorsen Biotechnology Co., Ltd 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 58
Shanghai Amole Biotechnology Co., Ltd. 58

View Latest Price from 2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SSR504734 HCl pictures 2026-07-15 SSR504734 HCl
615571-23-8
 $41.00-158.00 99.93% 10g TargetMol Chemicals Inc.
  • SSR504734 HCl pictures
  • SSR504734 HCl
    615571-23-8
  • $41.00-158.00
  • 99.93%
  • TargetMol Chemicals Inc.

2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride Spectrum

2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride(615571-23-8)1HNMR

615571-23-8 (2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride) Related Search:

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2-Chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride SSR504734 Compound 1549 SSR504734 HCl SSR 504734 hydrochloride 2-chloro-N-((S)-phenyl((S)-piperidin-2-yl)methyl)-3-(trifluoromethyl)benzamide hydrochloride 615571-23-8 C20H20ClF3N2OHCl