benzyl 2,4-difluorophenylcarbaMate
- CAS No.
- 112434-18-1
- Chemical Name:
- benzyl 2,4-difluorophenylcarbaMate
- Synonyms
- benzyl 2,4-difluorophenylcarbaMate;(2,4-Difluorophenyl)carbamic acid benzyl ester;Carbamic acid, N-(2,4-difluorophenyl)-, phenylmethyl ester
- CBNumber:
- CB22552745
- Molecular Formula:
- C14H11F2NO2
- Molecular Weight:
- 263.24
- MDL Number:
- MFCD21648243
- MOL File:
- 112434-18-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| BENZYL-(2,4-DIFLUOROPHENYL)CARBAMATE 95.00% | HCH0368557 | 5MG | $502.55 |
| Benzyl 2,4-difluorophenylcarbamate 97% | 071203 | 5g | $615 |
| Benzyl(2,4-difluorophenyl)carbamate | 2182AA | 5g | $1546 |
| benzyl(2,4-difluorophenyl)carbamate 95+% | CM128599 | 5g | $1036 |
| Benzyl(2,4-difluorophenyl)carbamate 97% | CD12179772 | 5g | $1097 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
benzyl 2,4-difluorophenylcarbaMate price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | HCH0368557 | BENZYL-(2,4-DIFLUOROPHENYL)CARBAMATE 95.00% | 112434-18-1 | 5MG | $502.55 | 2021-12-16 | Buy |
| Matrix Scientific | 071203 | Benzyl 2,4-difluorophenylcarbamate 97% | 112434-18-1 | 5g | $615 | 2021-12-16 | Buy |
| AK Scientific | 2182AA | Benzyl(2,4-difluorophenyl)carbamate | 112434-18-1 | 5g | $1546 | 2021-12-16 | Buy |
| Chemenu | CM128599 | benzyl(2,4-difluorophenyl)carbamate 95+% | 112434-18-1 | 5g | $1036 | 2021-12-16 | Buy |
| Crysdot | CD12179772 | Benzyl(2,4-difluorophenyl)carbamate 97% | 112434-18-1 | 5g | $1097 | 2021-12-16 | Buy |
benzyl 2,4-difluorophenylcarbaMate Chemical Properties,Uses,Production
Synthesis
367-25-9
501-53-1
112434-18-1
To a 250 mL round bottom flask was added 2,4-difluoroaniline (11.4 g, 4.62 mL, 45.4 mmol), dichloromethane (DCM, 103 mL) and pyridine (7.40 mL, 91 mmol). The reaction mixture was stirred at room temperature and benzyl chloroformate (8.15 mL, 54.5 mmol) was slowly added dropwise through the addition funnel. After the dropwise addition, the reaction mixture was continued to be stirred at room temperature overnight. Upon completion of the reaction, the mixture was poured into water and extracted with DCM. The organic phases were combined, washed sequentially with water and saturated saline, and then dried over anhydrous sodium sulfate. After filtration to remove the desiccant, the filtrate was concentrated under reduced pressure to afford benzyl (2,4-difluorophenyl)-carbamate (11.1 g, 42.2 mmol, 93% yield) as a white solid, which could be used for subsequent reactions without further purification.LC-MS (ESI, positive ion mode) analysis: calculated value of C14H11F2NO2 [M+H]+: 263.1; Measured value: 263.1. measured value [M+Na]+: 286.1. 1H NMR (400 MHz, DMSO-d6) δ ppm: 9.43 (br s, 1H), 7.51-7.66 (m, 1H), 7.24-7.46 (m, 6H), 7.01-7.12 (m, 1H), 5.15 (s, 2H).
References
[1] Tetrahedron Letters, 2006, vol. 47, # 36, p. 6393 - 6396
[2] Canadian Journal of Chemistry, 2009, vol. 87, # 2, p. 393 - 396
[3] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 10, p. 2215 - 2234
[4] Tetrahedron Letters, 2008, vol. 49, # 16, p. 2607 - 2610
[5] Patent: US2008/167338, 2008, A1. Location in patent: Page/Page column 44-45
benzyl 2,4-difluorophenylcarbaMate Preparation Products And Raw materials
Raw materials
Preparation Products
benzyl 2,4-difluorophenylcarbaMate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Alfa Chemical Co., Ltd | +8615838112936 | alfa10@alfachem.cn | China | 12920 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Credit Asia Chemical Co., Ltd. | +86 (21) 61124340 | China | 9756 | 58 | |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 12346 | 58 |
| Chengdu Research Accelerators Technology Co., Ltd. | 028-64353063 | reacchemical@163.com | China | 5253 | 58 |
| Yantai ShengKailun Chemical Technology Co., Ltd. | 13356901049 | 3119594100@qq.com | China | 7964 | 55 |
| Aikon International Limited | 025-58851090 15955137747 | sales01@aikonchem.com | China | 15949 | 58 |
| Nanjing crow LuNing pharmaceutical technology co., LTD | 13382066392 | CHINA | 4877 | 58 | |
| Shanghai Lanle Bird Industrial Co., Ltd. | 15021845385 | 765325601@qq.com | China | 3609 | 58 |
