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ChemicalBook >> CAS DataBase List >>1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL

1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL

1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL Structure
1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL structure
CAS No.
893755-98-1
Chemical Name:
1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL
Synonyms
1-(2-Pyrimidinyl)-4-piperidinol;1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL;4-Piperidinol, 1-(2-pyrimidinyl)-;4-Hydroxy-1-(2-pyrimidyl)piperidine;N-(2-Pyrimidinyl)-4-hydroxypiperidine;1,3-Benzodioxole-5-carboxaldehyde,9-methoxy-;1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL ISO 9001：2015 REACH;2-Naphthalenesulfonylchloride,5,6,7,8-tetrahydro-5,5,8,13-tetramethyl-
CBNumber:
CB2257374
Molecular Formula:
C9H13N3O
Molecular Weight:
179.22
MDL Number:
MFCD05864742
MOL File:
893755-98-1.mol
Last updated:2026-05-28 00:01:54
Product description Number Pack Size Price
1-Pyrimidin-2-yl-piperidin-4-ol 071775 1.00g $185
1-Pyrimidin-2-yl-piperidin-4-ol 071775 5.00g $399
1-Pyrimidin-2-yl-piperidin-4-ol 071775 10.00g $536
1-(Pyrimidin-2-yl)piperidin-4-ol 95+% P50328 250mg $80
1-(Pyrimidin-2-yl)piperidin-4-ol 95+% P50328 1g $140
Request For Quotation

1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL Properties

Boiling point 365.5±52.0 °C(Predicted)
Density 1.234±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 14.56±0.20(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C9H13N3O/c13-8-2-6-12(7-3-8)9-10-4-1-5-11-9/h1,4-5,8,13H,2-3,6-7H2
InChIKey ZATIGSFNFLXZAS-UHFFFAOYSA-N
SMILES N1(C2=NC=CC=N2)CCC(O)CC1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933599590

1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 071775 1-Pyrimidin-2-yl-piperidin-4-ol 893755-98-1 1.00g $185 2026-05-18 Buy
Matrix Scientific 071775 1-Pyrimidin-2-yl-piperidin-4-ol 893755-98-1 5.00g $399 2026-05-18 Buy
Matrix Scientific 071775 1-Pyrimidin-2-yl-piperidin-4-ol 893755-98-1 10.00g $536 2026-05-18 Buy
Synthonix P50328 1-(Pyrimidin-2-yl)piperidin-4-ol 95+% 893755-98-1 250mg $80 2026-05-06 Buy
Synthonix P50328 1-(Pyrimidin-2-yl)piperidin-4-ol 95+% 893755-98-1 1g $140 2026-05-06 Buy
Product number Packaging Price Buy
071775 1.00g $185 Buy
071775 5.00g $399 Buy
071775 10.00g $536 Buy
P50328 250mg $80 Buy
P50328 1g $140 Buy

1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL Chemical Properties,Uses,Production

Synthesis

4-Hydroxypiperidine

5382-16-1

2-Chloropyrimidine

1722-12-9

1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL

893755-98-1

Step 1: Synthesis of 1-(2-pyrimidinyl)-4-piperidinol (180) 4-Hydroxypiperidine (1.5 g, 14.7 mmol), 2-chloropyrimidine (1.5 g, 13.4 mmol) and diisopropylethylamine (6 mL, 33.5 mmol) were dissolved in 50 mL of acetonitrile. The reaction mixture was heated and stirred at 80 °C for 18 hours. After completion of the reaction, the mixture was concentrated to dryness under reduced pressure. The crude product was purified by fast column chromatography using a 0-60% ethyl acetate/hexane gradient elution to afford 2.1 g (81% yield) of target compound 180 as a white solid. 1H NMR (400 MHz, CDCl3): δ 8.28 (d, J = 4.6 Hz, 2H), 6.49 (t, J = 4.8 Hz, 1H), 4.49-4.33 (m, 2H), 4.01-3.88 (m, 1H), 3.37-3.21 (m, 2H), 2.02-1.90 (m, 2H), 1.60- 1.45 (m, 2H); LCMS (ESI): m/z 180 [M + H]+.

References

[1] Patent: WO2008/8895, 2008, A1. Location in patent: Page/Page column 155; 156
[2] Journal of Medicinal Chemistry, 2012, vol. 55, # 24, p. 10972 - 10994

1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL synthesis

116247-92-8
893755-98-1
Synthesis of 1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL from 1-PYRIMIDIN-2-YL-PIPERIDIN-4-ONE

1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL Preparation Products And Raw materials

Raw materials

1-PYRIMIDIN-2-YL-PIPERIDIN-4-ONE 2-Chloropyrimidine 4-Hydroxypiperidine N,N-Diisopropylethylamine Acetonitrile

Preparation Products

1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL Suppliers

Global( 45)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 18895 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Shandong Shining Medical Science and Technology Co., Ltd. 18668980106; 18866891188 xuandechem@126.com China 49 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40228 62
Amber MolTech LLC 086-010-62176588 amber@jyamber.com China 10151 56
NovoChemy Ltd. 021-31261262/ 49 (0)17662837245 sales@novochemy.com Germany 6328 58
Nanjing Norris-Pharm Technology Co., Ltd 18652989687 sales@norris-pharm.com China 8878 55
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Alchem Pharmtech,Inc. 		58
Dideu Industries Group Limited 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
Shandong Shining Medical Science and Technology Co., Ltd. 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Amber MolTech LLC 56
NovoChemy Ltd. 58
Nanjing Norris-Pharm Technology Co., Ltd 55

View Lastest Price from 1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL pictures 2025-11-18 1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL
893755-98-1
 US $1.10 / g 1g 99.00% 100 Tons Dideu Industries Group Limited

893755-98-1(1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL)Related Search:

Tebuconazole
1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL 1-(2-Pyrimidinyl)-4-piperidinol N-(2-Pyrimidinyl)-4-hydroxypiperidine 4-Piperidinol, 1-(2-pyrimidinyl)- 1-PYRIMIDIN-2-YL-PIPERIDIN-4-OL ISO 9001：2015 REACH 1,3-Benzodioxole-5-carboxaldehyde,9-methoxy- 2-Naphthalenesulfonylchloride,5,6,7,8-tetrahydro-5,5,8,13-tetramethyl- 4-Hydroxy-1-(2-pyrimidyl)piperidine 893755-98-1