ChemicalBook >> CAS DataBase List >>Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate

Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate

CAS No.
164161-49-3
Chemical Name:
Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate
Synonyms
Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate;Methyl 4-methoxy-2-nitro-5-(phenylmethoxy)benzoate;Benzoicacid,4-Methoxy-2-nitro-5-(phenylMethoxy)-,Methylester
CBNumber:
CB22597368
Molecular Formula:
C16H15NO6
Molecular Weight:
317.29
MDL Number:
MFCD17168894
MOL File:
164161-49-3.mol
MSDS File:
SDS
Last updated:2026-05-28 00:02:27
Product description Number Pack Size Price
Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 074744 1.00g $462
Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 074744 5.00g $1298
Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% M58666 250mg $54
Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% M58666 1g $58
Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% M58666 5g $60

Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate Properties

Boiling point 482.4±40.0 °C(Predicted)
Density 1.280
storage temp. Sealed in dry,Room Temperature
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 074744 Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 164161-49-3 1.00g $462 2026-05-18 Buy
Matrix Scientific 074744 Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 164161-49-3 5.00g $1298 2026-05-18 Buy
Synthonix M58666 Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% 164161-49-3 250mg $54 2026-05-06 Buy
Synthonix M58666 Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% 164161-49-3 1g $58 2026-05-06 Buy
Synthonix M58666 Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate 95+% 164161-49-3 5g $60 2026-05-06 Buy
Product number Packaging Price Buy
074744 1.00g $462 Buy
074744 5.00g $1298 Buy
M58666 250mg $54 Buy
M58666 1g $58 Buy
M58666 5g $60 Buy

Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate Chemical Properties,Uses,Production

Synthesis

Methyl 5-hydroxy-4-methoxy-2-nitrobenzoate

215659-03-3

Benzyl bromide

100-39-0

Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate

164161-49-3

The reaction was carried out with methyl 5-hydroxy-4-methoxy-2-nitrobenzoate (15.4 g, 68 mmol) and benzyl bromide (9.7 mL, 82 mmol) in the presence of cesium carbonate (44 g, 136 mmol) with stirring at room temperature in DMSO (200 mL) for 24 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (~2 L) and n-butanol (~100 mL). The organic layer was washed sequentially with water and brine, dried with magnesium sulfate, filtered and concentrated. The residue was purified by silica gel column chromatography (eluent ratio from 1:5 to 2:1 ethyl acetate-hexane) to afford methyl 2-nitro-4-methoxy-5-benzyloxybenzoate 20.2 g in 94% yield; MS (AP/CI): 286.1 (M + H)+.

References

[1] Patent: WO2008/20302, 2008, A2. Location in patent: Page/Page column 28
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 13, p. 4536 - 4547

215659-03-3
100-39-0
164161-49-3
Synthesis of Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate from Methyl 5-hydroxy-4-methoxy-2-nitrobenzoate and Benzyl bromide

Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate Suppliers

Global( 37)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131956 58
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42934 64
Shanghai civi chemical technology co.,Ltd 86-21-34053660 sale@labgogo.com China 9865 52
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6175 58
Shanghai Witofly Chemical Co.,Ltd sales@witofly.com China 2864 52
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7865 55
Hangzhou Trylead Chemical Technology Co.,LTD 0571-87086220 13516718938 zyf@trylead-chem.com China 300 64
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189 mychess007@163.com China 1994 55

Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate Spectrum

Benzoicacid,4-Methoxy-2-nitro-5-(phenylMethoxy)-,Methylester Methyl 5-Benzyloxy-4-Methoxy-2-nitrobenzoate Methyl 4-methoxy-2-nitro-5-(phenylmethoxy)benzoate 164161-49-3