ChemicalBook >> CAS DataBase List >>2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
- CAS No.
- 1256584-73-2
- Chemical Name:
- 2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
- Synonyms
- Aletinib impurity 14;Alectinib Impurity 14;Alecensa intermediate;Alectinib intermediate A;2-(4-yl-3-iodophenyl)-2-methylpropanoic acid;4-Ethyl-3-iodo-α,α-dimethylbenzeneacetic acid;2-(3-Iodo-4-ethylphenyl)-2-methylpropionic acid;2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid;Benzeneacetic acid, 4-ethyl-3-iodo-α,α-dimethyl-;2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid-7
- CBNumber:
- CB22623823
- Molecular Formula:
- C12H15IO2
- Molecular Weight:
- 318.15
- MDL Number:
- MFCD22571222
- MOL File:
- 1256584-73-2.mol
- MSDS File:
- SDS
Last updated:2026-07-25 07:39:42
| Product description | Number | Pack Size | Price |
| 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic Acid | 413746 | 10mg | $305 |
| 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic Acid | 413746 | 50mg | $531 |
| 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid >98% | E65929 | 1g | $16 |
| 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid >98% | E65929 | 5g | $20 |
| 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid >98% | E65929 | 25g | $60 |
| More product size | |||
| Boiling point | 369.6±27.0 °C(Predicted) |
|---|---|
| Density | 1.547±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C, protect from light |
| pka | 4.32±0.11(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C12H15IO2/c1-4-8-5-6-9(7-10(8)13)12(2,3)11(14)15/h5-7H,4H2,1-3H3,(H,14,15) |
| InChIKey | RUVGXZCQYVEAKQ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C(C1=CC=C(CC)C(I)=C1)(C)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| REACH Registrations | Active |
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 413746 | 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic Acid | 1256584-73-2 | 10mg | $305 | 2026-06-03 | Buy |
| Usbiological | 413746 | 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic Acid | 1256584-73-2 | 50mg | $531 | 2026-06-03 | Buy |
| Synthonix | E65929 | 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid >98% | 1256584-73-2 | 1g | $16 | 2026-05-06 | Buy |
| Synthonix | E65929 | 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid >98% | 1256584-73-2 | 5g | $20 | 2026-05-06 | Buy |
| Synthonix | E65929 | 2-(4-Ethyl-3-iodophenyl)-2-methylpropanoic acid >98% | 1256584-73-2 | 25g | $60 | 2026-05-06 | Buy |
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid Chemical Properties,Uses,Production
Description
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid is a pharmaceutical intermediate compound used in the preparation of anti-tumour drugs such as alectinib, erlotinib and hydrochloric acid neritinib.
Uses
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
Synthesis
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid is prepared by reacting 4-Ethyl-α,α-dimethylbenzeneacetic acid with N-Iodosuccinimide in Acetic acid for 2h.
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 164)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +86-13382787392 | sales@aeechem.com | China | 10002 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2945 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3970 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 | contact@trustwe.com | China | 5757 | 58 |
| Hefei Hangang Pharmaceutical Technology Co., Ltd. | +8618062405514 | ada@ipurechemical.com | China | 10224 | 58 |
| Shanghai Rochi Pharmaceutical Co.,Ltd. | 21-38751876 +8615000076078 | info@rochipharma.com | China | 504 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15050 | 58 |
| SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD | +86-17691239725 +86-15529797525 | lijiasheng@ltom.com | China | 185 | 58 |
View Lastest Price from 2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-31 | 4-Ethyl-3-iodo-alpha,alpha-dimethylbenzeneacetic acid
1256584-73-2
|
$5.00 | 1kg | ≥99% | 200mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2026-07-25 | 2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
1256584-73-2
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-02-02 | 2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
1256584-73-2
|
$10000.00-200000.00 | 1KG | 99.0%HPLC | 500tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 4-Ethyl-3-iodo-alpha,alpha-dimethylbenzeneacetic acid
1256584-73-2
- $5.00
- ≥99%
- Jinan Finer Chemical Co., Ltd
-
- 2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
1256584-73-2
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
1256584-73-2
- $10000.00-200000.00
- 99.0%HPLC
- Shaanxi Dideu Medichem Co. Ltd
1256584-73-2(2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid)Related Search:
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid
2-(4-ethyl-3-iodophenyl)-2-Methylpropanoic acid-7
4-Ethyl-3-iodo-α,α-dimethylbenzeneacetic acid
4-Ethyl-3-iodo-alpha,alpha-dimethylbenzeneacetic acid
2-(3-Iodo-4-ethylphenyl)-2-methylpropionic acid
Alecensa intermediate
Alectinib Impurity 14
Benzeneacetic acid, 4-ethyl-3-iodo-α,α-dimethyl-
2-(4-ethyl-3-iodophenyl)-2-methylpropanoic acid
(alectinib intermediate)
4-?Ethyl-?3-?iodo-?α,?α-?dimethylbenzeneaceti?c acid
Alectinib intermediate A
Aletinib impurity 14
2-(4-yl-3-iodophenyl)-2-methylpropanoic acid
1256584-73-2
1256584-73-2
