Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid

6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid

6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid Structure
6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid structure
CAS No.
407587-33-1
Chemical Name:
6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid
Synonyms
CaCCinh-A01;TMEM16 BLOCKER I;CaCCinh-A01 ，S0125;CaCCinh-A01, 10 mM in DMSO;CaCC(inh)-A01, TMEM16 Blocker I.;CACCINH-A01; CACC(INH)-A01, TMEM16 BLOCKER I.;6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid;6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid;Benzo[b]thiophene-3-carboxylic acid, 6-(1,1-dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro-
CBNumber:
CB22631367
Molecular Formula:
C18H21NO4S
Molecular Weight:
347.43
MDL Number:
MFCD02919058
MOL File:
407587-33-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18
Product description Number Pack Size Price
CaCCinh-A01 ≥98% (HPLC) SML0916 5mg $129
CaCCinh-A01 ≥98% (HPLC) SML0916 25mg $527
Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 The Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 controls the biological activity of Calcium-activated Chloride Channel. 208293 10 mg $202
InSolution Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 - CAS 407587-33-1 - Calbiochem 5.08628 5mg $129
CaCC(inh)-A01 ≥98% 21922 5mg $74
More product size
Request For Quotation

6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid Properties

Boiling point 429.7±45.0 °C(Predicted)
Density 1.305±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble20mg/mL, clear
form powder
pka 4.49±0.40(Predicted)
color white to beige
InChI 1S/C18H21NO4S/c1-18(2,3)10-6-7-11-13(9-10)24-16(14(11)17(21)22)19-15(20)12-5-4-8-23-12/h4-5,8,10H,6-7,9H2,1-3H3,(H,19,20)(H,21,22)
InChIKey ACLUEOBQFRYTQS-UHFFFAOYSA-N
SMILES [s]1c2c(c(c1NC(=O)c3[o]ccc3)C(=O)O)CCC(C2)C(C)(C)C
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
WGK Germany  3
Storage Class 11 - Combustible Solids

6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid price More Price(71)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0916 CaCCinh-A01 ≥98% (HPLC) 407587-33-1 5mg $129 2026-04-30 Buy
Sigma-Aldrich SML0916 CaCCinh-A01 ≥98% (HPLC) 407587-33-1 25mg $527 2026-04-30 Buy
Sigma-Aldrich 208293 Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 The Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 controls the biological activity of Calcium-activated Chloride Channel. 407587-33-1 10 mg $202 2026-04-30 Buy
Sigma-Aldrich 5.08628 InSolution Calcium-activated Chloride Channel Inhibitor, CaCCinh-A01 - CAS 407587-33-1 - Calbiochem 407587-33-1 5mg $129 2022-05-15 Buy
Cayman Chemical 21922 CaCC(inh)-A01 ≥98% 407587-33-1 5mg $74 2026-04-30 Buy
Product number Packaging Price Buy
SML0916 5mg $129 Buy
SML0916 25mg $527 Buy
208293 10 mg $202 Buy
5.08628 5mg $129 Buy
21922 5mg $74 Buy

6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid Chemical Properties,Uses,Production

Uses

CaCC(inh)-A01 is a potent, selective class A inhibitor of calcium-activated chloride channels (CaCCs).

Biochem/physiol Actions

CaCCinh-A01 is a TMEM16A (transmembrane member 16A) inhibitor. It also blocks anoctamin-1 (ANO1) and decreases cell viability and represses cell migration.

in vivo

CaCCinh-A01 (vein injection; 5 mg/kg; caudal vein injection within 15 min after the onset of reperfusion) significantly reduces infarction when compared with MCAO-saline treatment at 24 h or 72 h in middle cerebral artery occlusion model in mice[3].

Animal Model:Two-month-old male C57/BL6J mice[3]
Dosage:5 mg/kg
Administration:Vein injection; 5 mg/kg; caudal vein injection within 15 min after the onset of reperfusion
Result:Attenuated brain infarct size, improved neurological outcomes and lowered BBB permeability after ischemic stroke in mice.

storage

Store at -20°C

6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid Suppliers

Global( 112)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
BOC Sciences 		16314854226; +16314854226 inquiry@bocsci.com United States 19853 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39037 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131956 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
BOC Sciences 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58

View Lastest Price from 6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CaCCinh-A01 pictures 2026-07-14 CaCCinh-A01
407587-33-1
 $52.00-189.00 99.36% 10g TargetMol Chemicals Inc.
6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid pictures 2020-01-14 6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid
407587-33-1
 $9.80 1g ≥99% 100kg Career Henan Chemical Co
  • CaCCinh-A01 pictures
  • CaCCinh-A01
    407587-33-1
  • $52.00-189.00
  • 99.36%
  • TargetMol Chemicals Inc.

6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid Spectrum

6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid(407587-33-1)1HNMR

407587-33-1(6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid)Related Search:

2-({[3-(aminocarbonyl)-4,5,6,7-tetrahydro-1-benzothien-2-yl]amino}carbonyl)benzoic acid methyl 2-(furan-2-carboxamido)-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate SALOR-INT L420239-1EA ethyl 2-(2-furoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate methyl 2-[(3-methyl-1-benzofuran-2-carbonyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
2-ACETYLAMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID

1of2

6-tert-butyl-2-(furan-2-carboxaMido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid CaCCinh-A01 6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid TMEM16 BLOCKER I CaCC(inh)-A01, TMEM16 Blocker I. CACCINH-A01; CACC(INH)-A01, TMEM16 BLOCKER I. Benzo[b]thiophene-3-carboxylic acid, 6-(1,1-dimethylethyl)-2-[(2-furanylcarbonyl)amino]-4,5,6,7-tetrahydro- CaCCinh-A01, 10 mM in DMSO CaCCinh-A01 ，S0125 407587-33-1