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Ethyl 3,3-difluorobutyrate

CAS No.
2368-93-6
Chemical Name:
Ethyl 3,3-difluorobutyrate
Synonyms
Ethyl 3,3-difluorobutanoate;Ethyl 3,3-difluorobutyrate;3,3-difluoroethyl butyrate;Ethyl 3,3-difluorobutyrate >=96.0%;3,3-Difluorobutyric acid ethyl ester;Butanoic acid, 3,3-difluoro-, ethyl ester
CBNumber:
CB22638245
Molecular Formula:
C6H10F2O2
Molecular Weight:
152.14
MDL Number:
MFCD15144889
MOL File:
2368-93-6.mol
MSDS File:
SDS
Last updated:2026-05-28 00:04:02

Ethyl 3,3-difluorobutyrate Properties

Boiling point 135 °C
Density 1.1094 g/cm3(Temp: 25 °C)
Flash point 55℃
form liquid
BRN 1759658
InChI 1S/C6H10F2O2/c1-3-10-5(9)4-6(2,7)8/h3-4H2,1-2H3
InChIKey JSMRUPPAFDYIRD-UHFFFAOYSA-N
SMILES CCOC(=O)CC(C)(F)F
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H302+H332-H315-H319-H335
Precautionary statements  P210-P233-P301+P312-P303+P361+P353-P304+P340+P312-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  10-18-20/22-36/37/38
Safety Statements  26
RIDADR  UN 3272 3 / PGIII
WGK Germany  3
HazardClass  3
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

Ethyl 3,3-difluorobutyrate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 725781 Ethyl 3,3-difluorobutyrate ≥96.0% 2368-93-6 500mg $91.4 2023-06-20 Buy
aablocks AA002O2S ETHYL 3,3-DIFLUOROBUTYRATE 97% 2368-93-6 250mg $248 2026-05-28 Buy
aablocks AA002O2S ETHYL 3,3-DIFLUOROBUTYRATE 97% 2368-93-6 1g $295 2026-05-28 Buy
aablocks AA002O2S ETHYL 3,3-DIFLUOROBUTYRATE 97% 2368-93-6 5g $528 2026-05-28 Buy
aablocks AA002O2S ETHYL 3,3-DIFLUOROBUTYRATE 97% 2368-93-6 25g $1170 2026-05-28 Buy
Product number Packaging Price Buy
725781 500mg $91.4 Buy
AA002O2S 250mg $248 Buy
AA002O2S 1g $295 Buy
AA002O2S 5g $528 Buy
AA002O2S 25g $1170 Buy

Ethyl 3,3-difluorobutyrate Chemical Properties,Uses,Production

Uses

Ethyl 3,3-Difluorobutanoate is used in the preparation of fluoroalkyl esters and carboxylic acids using SF4-mediated deoxofluorination reactions of β-ketoesters and hydrolysis and management of the hazards of SF4 usage.

141-97-9
2368-93-6
Synthesis of Ethyl 3,3-difluorobutyrate from Ethyl acetoacetate

Ethyl 3,3-difluorobutyrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Chengdu 3S Pharmaceutical Technology Co., Ltd. 028-62577698; 19950139520 cd_chemical@126.com China 292 56
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
BTC Pharmaceutical CO. Ltd +86-15716293042 15716293042 info@btcpharm.com China 823 55
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39866 58
Anhui Henuo Biotechnology Co., Ltd 18455579438 China 16684 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 6206333 13167063860 anhua.mao@aladdin-e.com China 43293 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. 025-66061636 19370895928 qqyang@aikonchem.com China 9995 58
Anhui Jing Tong Pharmaceutical Co.LTD 13675155016 tongtf110@sina.com China 4281 58
Aladdin Scientific tp@aladdinsci.com United States 50089 58
Ethyl 3,3-difluorobutyrate 3,3-Difluorobutyric acid ethyl ester Ethyl 3,3-difluorobutyrate >=96.0% Ethyl 3,3-difluorobutanoate Butanoic acid, 3,3-difluoro-, ethyl ester 3,3-difluoroethyl butyrate 2368-93-6