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ChemicalBook >> CAS DataBase List >>[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]-

[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]-

[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]- Structure
[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]- structure
CAS No.
252920-94-8
Chemical Name:
[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]-
Synonyms
ALX-001;GW 427353;Solabegron-d8;Solabegron-d8 HCl;Solabegron 13C2 D4;Solabegron, 10 mM in DMSO;LLDXOPKUNJTIRF-QFIPXVFZSA-N;Tilorone oxime dihydrochloride;inhibit,GW-427353,Inhibitor,Adrenergic Receptor,GW427353,Beta Receptor,Solabegron;1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]-
CBNumber:
CB22648637
Molecular Formula:
C23H23ClN2O3
Molecular Weight:
410.89
MDL Number:
MOL File:
252920-94-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]- Properties

Boiling point 672.4±55.0 °C(Predicted)
Density 1.300±0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility DMSO: 250 mg/mL (608.44 mM)
form Solid
pka 4.14±0.10(Predicted)
FDA UNII 55P6YH9O6N

[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth CKA92094 Solabegron 252920-94-8 2mg $250 2026-06-04 Buy
Biosynth CKA92094 Solabegron 252920-94-8 1mg $250 2026-06-04 Buy
Biosynth CKA92094 Solabegron 252920-94-8 5mg $299.85 2026-06-04 Buy
Biosynth CKA92094 Solabegron 252920-94-8 10mg $524.7 2026-06-04 Buy
Biosynth CKA92094 Solabegron 252920-94-8 25mg $749.5 2026-06-04 Buy
Product number Packaging Price Buy
CKA92094 2mg $250 Buy
CKA92094 1mg $250 Buy
CKA92094 5mg $299.85 Buy
CKA92094 10mg $524.7 Buy
CKA92094 25mg $749.5 Buy

[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]- Chemical Properties, Uses, Production

Uses

Antidiabetic (β3 adrenoreceptor agonist).

Uses

Solabegron functions as a synthetic drug currently utilized in the treatment of urinary incontinence in men that are in phase III and onwards.

Definition

ChEBI: Solabegron is a carboxybiphenyl that is [biphenyl]-3-carboxylic acid carrying a (2-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}ethyl)nitrilo group at the 3' position. A selective beta3-adrenergic receptor agonist currently in clinical development for the treatment of overactive bladder and irritable bowel syndrome. It has a role as a beta-adrenergic agonist. It is a secondary alcohol, a substituted aniline, a member of monochlorobenzenes, a secondary amino compound and a carboxybiphenyl.

in vivo

Solabegron (GW427353) at 3 mg/kg i.v. evokes an increase in micturition volume threshold that prevented the acetic acid-evoked decreases in dogs. The low dose (1 mg/kg) shows no significant activity[1].

Animal Model:Adult female beagle dogs (6-10 kg)[1].
Dosage:1, 3 mg/kg.
Administration:I.V. once.
Result:Dosage of 3 mg/kg evoked an increase in micturition volume threshold.

IC 50

β adrenergic receptor

[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]- Preparation Products And Raw materials

Raw materials

Preparation Products

[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]- Suppliers

Global Suppliers ( 37)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 18916372613 yanzihan@shyuanye.com China 87240 60
Chengdu Senior Pharma Technology Co.Ltd. +86-0838-2319818 +86-15982001943 seniorpharma@163.com China 460 55
Aikon International Limited 025-58859352 13913916777 dt3@aikonchem.com China 15490 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49299 58
Shanghai Luofa Biochemical Technology Co., Ltd. 021-51111890 15317326293 sales@molnova.com China 4183 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Wuhan Topule +86-02787215551 19945035818 2936752263@qq.com China 7984 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Supplier Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 60
Chengdu Senior Pharma Technology Co.Ltd. 55
Aikon International Limited 58
TargetMol Chemicals Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58
Shanghai Luofa Biochemical Technology Co., Ltd. 58
Energy Chemical 58
Wuhan Topule 58
Beijing Jin Ming Biotechnology Co., Ltd. 58

View Latest Price from [1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Solabegron pictures 2026-07-15 Solabegron
252920-94-8
 $53.00-273.00 98.99% 10g TargetMol Chemicals Inc.
Solabegron pictures 2026-07-15 Solabegron
252920-94-8
 $53.00-273.00 98.99% 10g TargetMol Chemicals Inc.
  • Solabegron pictures
  • Solabegron
    252920-94-8
  • $53.00-273.00
  • 98.99%
  • TargetMol Chemicals Inc.
  • Solabegron pictures
  • Solabegron
    252920-94-8
  • $53.00-273.00
  • 98.99%
  • TargetMol Chemicals Inc.

[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]- Spectrum

[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]-(252920-94-8)1HNMR

252920-94-8 ([1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]-) Related Search:

Phenylephrine Metoprolol Mirabegron NADOLOL Salbutamol
(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride

1of2

[1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]- Tilorone oxime dihydrochloride LLDXOPKUNJTIRF-QFIPXVFZSA-N GW 427353 Solabegron-d8 HCl Solabegron 13C2 D4 Solabegron-d8 3 '- [[2 - [(2R) - 2 - (3-chlorophenyl) - 2-hydroxyethyl] amino] ethyl] amino] - [1,1' - biphenyl] - 3-carboxylic acid inhibit,GW-427353,Inhibitor,Adrenergic Receptor,GW427353,Beta Receptor,Solabegron 1,1'-Biphenyl]-3-carboxylicacid,3'-[[2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]aMino]ethyl]aMino]- Solabegron, 10 mM in DMSO ALX-001 252920-94-8