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ChemicalBook >> CAS DataBase List >>Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate

Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate

Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate Structure
Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate structure
CAS No.
319442-19-8
Chemical Name:
Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate
Synonyms
ethyl 4-oxo-4aH-thieno[3,2-d]pyrimidine-2-carboxylate;Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate;Thieno[3,2-d]pyrimidine-2-carboxylic acid, 3,4-dihydro-4-oxo-, ethyl ester;4-oxy-3,4-dihydrothiophenebenzo[3,2-d]pyrimidine-2-carboxylic acidethyl ester
CBNumber:
CB22650856
Molecular Formula:
C9H8N2O3S
Molecular Weight:
224.24
MDL Number:
MFCD21608026
MOL File:
319442-19-8.mol
MSDS File:
SDS
Last updated:2026-05-28 00:10:26
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Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate Properties

storage temp. 2-8°C(protect from light)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P501-P261-P272-P280-P302+P352-P362+P364-P333+P313

Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 119589 Ethyl 4-oxo-3,4-dihydrothieno-[3,2-d]pyrimidine-2-carboxylate 319442-19-8 250.00mg $36 2026-05-18 Buy
Matrix Scientific 119589 Ethyl 4-oxo-3,4-dihydrothieno-[3,2-d]pyrimidine-2-carboxylate 319442-19-8 1.00g $101 2026-05-18 Buy
Matrix Scientific 119589 Ethyl 4-oxo-3,4-dihydrothieno-[3,2-d]pyrimidine-2-carboxylate 319442-19-8 5.00g $351 2026-05-18 Buy
aablocks AA00CM29 Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate 98% 319442-19-8 250mg $24 2026-05-28 Buy
aablocks AA00CM29 Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate 98% 319442-19-8 1g $72 2026-05-28 Buy
Product number Packaging Price Buy
119589 250.00mg $36 Buy
119589 1.00g $101 Buy
119589 5.00g $351 Buy
AA00CM29 250mg $24 Buy
AA00CM29 1g $72 Buy

Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate Chemical Properties,Uses,Production

Synthesis

Methyl 3-amino-2-thiophenecarboxylate

22288-78-4

Ethyl cyanoformate

623-49-4

Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate

319442-19-8

Step A: Methyl 3-amino-2-thiophenecarboxylate (3.0 g, 19 mmol) was dissolved in acetic acid (24 mL), followed by the sequential addition of concentrated hydrochloric acid (2.4 mL) and ethyl cyanoformate (3.78 g, 38 mmol). The resulting inhomogeneous mixture was heated and stirred at 70 °C for 3 h. After completion of the reaction, it was cooled to room temperature. The solid generated in the reaction was collected by filtration and washed with deionized water. The filtrate was adjusted to a pH of about 5 with 1N NaOH solution, at which point a solid precipitated, and the precipitate was collected by filtration and again washed with deionized water. The two collected solids were combined and dried overnight in a vacuum drying oven to give the final ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-2-carboxylate (2.69 g, 63% yield).

References

[1] Patent: WO2012/30894, 2012, A1. Location in patent: Page/Page column 89-90

Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate Preparation Products And Raw materials

Raw materials

Methyl 3-amino-2-thiophenecarboxylate Ethyl cyanoformate Hydrochloric acid Acetic acid

Preparation Products

Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate Suppliers

Global( 25)Suppliers
Supplier Tel Email Country ProdList Advantage
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Jiangsu aikang biomedical research and development co., LTD 025-58859352 17714375163 qzhang@aikonchem.com China 15525 58
Henan Alpha Chemical Co., Ltd. 0371-55055611 18137792234 3957071458@qq.com China 9994 58
Henan Alfa Chemical Co., Ltd +8618339805032 sale03@alfachem.cn China 9872 58
Zhejiang Lianshuo Biotechnology Co., Ltd. 18616526224 lianshuo@vip.126.com China 9605 58
Shanghai Amico Chemicals Co. LTD 微信 18019252918 18019252918 1454668768@qq.com China 14933 58
Jinan ponder chemical co. LTD 0531-0000 thinklifescience@163.com China 19684 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49299 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Shanghai Ruipu Medical Technology Co., Ltd 15895968936 1018762393@qq.com China 9992 58
Supplier Advantage
Amadis Chemical Company Limited 58
Jiangsu aikang biomedical research and development co., LTD 58
Henan Alpha Chemical Co., Ltd. 58
Henan Alfa Chemical Co., Ltd 58
Zhejiang Lianshuo Biotechnology Co., Ltd. 58
Shanghai Amico Chemicals Co. LTD 58
Jinan ponder chemical co. LTD 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58
Energy Chemical 58
Shanghai Ruipu Medical Technology Co., Ltd 58

Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate Spectrum

Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate(319442-19-8)1HNMR

319442-19-8(Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate)Related Search:

Methyl 4-oxotetrahydro-2H-pyran-3-carboxylate TERT BUTYL 4-OXOBUTANOATE Ethyl 4-oxotetrahydro-2H-pyran-3-carboxylate CYCLOHEXANECARBONITRILE, 4-OXO- 4-Hydroxy-quinoline-8-carboxylic acid Methyl ester
2-methylthieno[3,2-d]pyrimidin-4(3H)-one

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Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate Thieno[3,2-d]pyrimidine-2-carboxylic acid, 3,4-dihydro-4-oxo-, ethyl ester ethyl 4-oxo-4aH-thieno[3,2-d]pyrimidine-2-carboxylate 4-oxy-3,4-dihydrothiophenebenzo[3,2-d]pyrimidine-2-carboxylic acidethyl ester 319442-19-8