(S)-b-AMino-4-chloro-benzeneethanol
- CAS No.
- 191109-51-0
- Chemical Name:
- (S)-b-AMino-4-chloro-benzeneethanol
- Synonyms
- (S)-2-Amino-2-(4-chlorophenyl)ethan-1-ol;(S)-b-AMino-4-chloro-benzeneethanol;(S)-2-aMino-2-(4-chlorophenyl)ethanol;(2S)-2-Amino-2-(4-chlorophenyl)ethanol;Benzeneethanol, β-amino-4-chloro-, (βS)-;(2S)-2-AMINO-2-(4-CHLOROPHENYL)ETHAN-1-OL;(S)-1-(4-chlorophenyl)-2-hydroxyethylamine;(S)-2-Amino-2-(4-chlorophenyl)ethan-1-ol - [A91747]
- CBNumber:
- CB22684222
- Molecular Formula:
- C8H10ClNO
- Molecular Weight:
- 171.6241
- MDL Number:
- MFCD09253716
- MOL File:
- 191109-51-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (S)-b-Amino-4-chloro-benzeneethanol 98% | OR452154 | 100mg | $21 |
| (S)-b-Amino-4-chloro-benzeneethanol 98% | OR452154 | 250mg | $29 |
| (S)-b-Amino-4-chloro-benzeneethanol 98% | OR452154 | 1g | $105 |
| (S)-b-Amino-4-chloro-benzeneethanol 98% | OR452154 | 5g | $429 |
| (S)-2-Amino-2-(4-chlorophenyl)ethanol 97%EE | AS87493-A | 1g | $165 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| HS Code | 2922190090 |
(S)-b-AMino-4-chloro-benzeneethanol price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR452154 | (S)-b-Amino-4-chloro-benzeneethanol 98% | 191109-51-0 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR452154 | (S)-b-Amino-4-chloro-benzeneethanol 98% | 191109-51-0 | 250mg | $29 | 2026-06-04 | Buy |
| Apolloscientific | OR452154 | (S)-b-Amino-4-chloro-benzeneethanol 98% | 191109-51-0 | 1g | $105 | 2026-06-04 | Buy |
| Apolloscientific | OR452154 | (S)-b-Amino-4-chloro-benzeneethanol 98% | 191109-51-0 | 5g | $429 | 2026-06-04 | Buy |
| Activate Scientific | AS87493-A | (S)-2-Amino-2-(4-chlorophenyl)ethanol 97%EE | 191109-51-0 | 1g | $165 | 2026-06-04 | Buy |
(S)-b-AMino-4-chloro-benzeneethanol Chemical Properties,Uses,Production
Synthesis
67336-19-0
191109-51-0
The general procedure for the synthesis of (S)-2-amino-2-(4-chlorophenyl)ethanol from (S)-4-chlorophenylglycine was as follows: to a solution of (S)-2-amino-2-(4-chlorophenyl)acetic acid (10.0 g, 53.9 mmol) in tetrahydrofuran (THF, 216 mL) was slowly added dropwise to a solution of (S)-2-amino-2-(4-chlorophenyl)acetic acid (10.0 g, 53.9 mmol) in the presence of a 1.0 M borane tetrahydrofuran complex (216 mL. 216 mmol) over 45 min. After removal of the ice bath, the reaction mixture was continued to be stirred at room temperature for 3.25 hours. Subsequently, water (6.79 mL, 377 mmol) was slowly added followed by sodium hydroxide solution (40.4 mL, 202 mmol) dropwise over 15 minutes. The reaction mixture was heated to 65 °C and stirred at this temperature for 18 hours. After completion of the reaction, the solvent was removed by concentration under reduced pressure. The residue was dissolved in dichloromethane (DCM, 500 mL), the organic phase was separated and washed with deionized water (200 mL). The aqueous phase was further extracted with dichloromethane (2 x 250 mL). All organic phases were combined, dried with anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to afford (S)-2-amino-2-(4-chlorophenyl)ethanol as a white solid (8.55 g, 92% yield). The product was characterized by LC-MS and 1H NMR: the calculated exact mass (C8H10ClNO) was 171.1, and the measured LC-MS m/z (%) was 172.2 ([M+H]+, 35Cl, 100) and 174.2 ([M+H]+, 37Cl, 33); 1H NMR (400 MHz, methanol-d4) δ ppm 3.47- 3.57 (m, 1H), 3.59-3.69 (m, 1H), 3.93 (dd, J=7.58,5.05Hz, 1H), 7.23-7.42 (m, 4H).
References
[1] Patent: WO2009/58300, 2009, A1. Location in patent: Page/Page column 53-54
(S)-b-AMino-4-chloro-benzeneethanol Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-b-AMino-4-chloro-benzeneethanol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aromsyn Co., Ltd. | +86-0571-85585865 +86-13336024896 | CB@aromsyn.com | China | 19176 | 58 |
| Golden Pharma Co., Limited | +86-18958062155 | sales@zjgoldpharm.com | China | 5893 | 58 |
| Tianjin Xinghan Biotechnology Co., Ltd | +86-18698089028 | 1725517238@qq.com | China | 2479 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7885 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Amatek Scientific Co. Ltd. | 0512-56316828 4008675858 | sales@amateksci.com | China | 9851 | 55 |
| LABTER PHARMATECH(BEIJING) CO.,LTD | 010-56330744 18310155299 | sales@labter.com.cn | China | 19999 | 55 |
