5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
- CAS No.
- 1052114-81-4
- Chemical Name:
- 5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
- Synonyms
- 5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic ac;5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid;5-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-Pyridinecarboxylic acid;3-Pyridinecarboxylic acid, 5-(4-fluorophenyl)-1,4-dihydro-4-oxo-
- CBNumber:
- CB22684499
- Molecular Formula:
- C12H8FNO3
- Molecular Weight:
- 233.2
- MDL Number:
- MFCD28965085
- MOL File:
- 1052114-81-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA008ZSJ | 5-(4-Fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid 98% | 1052114-81-4 | 250mg | $34 | 2026-05-28 | Buy |
| aablocks | AA008ZSJ | 5-(4-Fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid 98% | 1052114-81-4 | 1g | $86 | 2026-05-28 | Buy |
| aablocks | AA008ZSJ | 5-(4-Fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid 98% | 1052114-81-4 | 5g | $398 | 2026-05-28 | Buy |
| ACHEMBLOCK | S83690 | 5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid 97% | 1052114-81-4 | 1G | $140 | 2026-05-27 | Buy |
| ACHEMBLOCK | S83690 | 5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid 97% | 1052114-81-4 | 5G | $655 | 2026-05-27 | Buy |
5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid Chemical Properties,Uses,Production
Synthesis
1052114-80-3
1052114-81-4
Example A8: Example A7 (0.750 g, 2.87 mmol) was suspended in 3 M NaOH aqueous solution (7.5 mL, 22.50 mmol) and heated to reflux at 100 °C for 1.5 hrs. Upon completion of the reaction, the mixture was cooled to room temperature and slowly acidified to pH 2 with 3 M aqueous HCl. The precipitated white solid was collected by vacuum filtration and washed with deionized water and dried to afford 5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid (669 mg, 100% yield). The product was analyzed by mass spectrometry (ESI), m/z: 234.1 ([M + H]+).
References
[1] Patent: WO2014/145004, 2014, A1. Location in patent: Paragraph 0111
[2] Journal of Medicinal Chemistry, 2008, vol. 51, # 17, p. 5330 - 5341
[3] Patent: WO2009/94417, 2009, A1. Location in patent: Page/Page column 28; 35-36
[4] Patent: WO2014/713, 2014, A1. Location in patent: Page/Page column 38
5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid Preparation Products And Raw materials
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