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Carboxyethylgermanium sesquioxide

CAS No.
12758-40-6
Chemical Name:
Carboxyethylgermanium sesquioxide
Synonyms
99.7%;GE 132;SK-818;Serocion;REPAGERMANIUM;proxigermanium;Germanium Ge 132;ORGANIC GERMANIUM;Germanium Sesquoxide;GERMANIUM SESQUIOXIDE
CBNumber:
CB2271237
Molecular Formula:
C6H10Ge2O7
Molecular Weight:
339.37
MDL Number:
MFCD00049319
MOL File:
12758-40-6.mol
MSDS File:
SDS
Last updated:2026-01-13 11:15:51
Product description Number Pack Size Price
Bis(2-carboxyethylgermanium(IV) sesquioxide) 99% 396265 5g $75.39
Bis[2-carboxyethylgermanium(IV)] Sesquioxide >98.0%(T) B1367 5g $86
Bis[2-carboxyethylgermanium(IV)] Sesquioxide >98.0%(T) B1367 25g $283
Bis(carboxyethylgerm​anium)Sesquioxide B415290 25g $275
Bis[2-carboxyethylgermanium(IV)]sesquioxide,≥98%(Assaybytitration) ≥98%(Assaybytitration) 40578 25G $290.04
More product size

Carboxyethylgermanium sesquioxide Properties

Melting point 320°C
storage temp. -20°C Freezer, Under inert atmosphere
solubility Aqueous Base (Sparingly)
pka 3.6(at 25℃)
form Solid
color White to Off-White
Specific Gravity 1.280
Odor wh. odorless powd.
Water Solubility Slightly soluble in water.
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
Merck 14,7795
Cosmetics Ingredients Functions SKIN CONDITIONING
InChI 1S/C6H10Ge2O7/c9-5(10)1-3-7(13)15-8(14)4-2-6(11)12/h1-4H2,(H,9,10)(H,11,12)
InChIKey XEABSBMNTNXEJM-UHFFFAOYSA-N
SMILES OC(=O)CC[Ge](=O)O[Ge](=O)CCC(O)=O
CAS DataBase Reference 12758-40-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 1Q2P9TO9Q7
EPA Substance Registry System 2-(Carboxyethyl)germanium sesquioxide (12758-40-6)
UNSPSC Code 12352103
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H303-H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE Eyeshields, Gloves, type N95 (US)
Risk Statements  36/37/38
Safety Statements  26-36/37/39
WGK Germany  2
RTECS  UA2459750
TSCA  TSCA listed
HS Code  2931.90.9051
Storage Class 11 - Combustible Solids
Toxicity LD50 i.p. in mice: 2.8 g/kg (Brutkiewicz)
NFPA 704
1
0 0

Carboxyethylgermanium sesquioxide price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 396265 Bis(2-carboxyethylgermanium(IV) sesquioxide) 99% 12758-40-6 5g $75.39 2025-07-31 Buy
TCI Chemical B1367 Bis[2-carboxyethylgermanium(IV)] Sesquioxide >98.0%(T) 12758-40-6 5g $86 2025-07-31 Buy
TCI Chemical B1367 Bis[2-carboxyethylgermanium(IV)] Sesquioxide >98.0%(T) 12758-40-6 25g $283 2025-07-31 Buy
TRC B415290 Bis(carboxyethylgerm​anium)Sesquioxide 12758-40-6 25g $275 2021-12-16 Buy
Chem-Impex 40578 Bis[2-carboxyethylgermanium(IV)]sesquioxide,≥98%(Assaybytitration) ≥98%(Assaybytitration) 12758-40-6 25G $290.04 2021-12-16 Buy
Product number Packaging Price Buy
396265 5g $75.39 Buy
B1367 5g $86 Buy
B1367 25g $283 Buy
B415290 25g $275 Buy
40578 25G $290.04 Buy

Carboxyethylgermanium sesquioxide Chemical Properties,Uses,Production

Description

Propagermanium, the first organogermanium compound marketed as a pharmaceutical, is indicated for the oral treatment of chronic hepatitis B. Propagermanium is reported to enhance production of interferon α/β in virus infected mice and in human peripheral blood mononuclear cells but does not inhibit the growth of various DNA or RNA viruses in vitro. Therefore, enhancement of the host immune system against virus infection was proposed to be responsible for its antiviral activity. Propagermanium also exhibits potent antitumor activity, reportedly via stimulation of T lymphocytes to produce a lyrnphokine (s), possibly interferon-y, which induces the generation and activation of cytotoxic macrophages leading to elimination of tumor cells. Propagermanium has been reported to regulate calcium metabolism and to alleviate cancerous pain and osteocope.

Originator

Sanwa Kagaku (Japan)

Uses

A bifunctional metalloligand with metal-C (Ge-C) bonds,bis(carboxyethylgermanium) sesquioxide, has been used to make two metal-organometallic frameworks (MOMFs). bis-(carboxyethylgermanium)sesquioxide is a as a promising anti-oxidative agent. Bis(carboxyethylgermanium) sesquioxide induce INF-γ and has undergone clinical trials with promising preclinical results.

Uses

Bis(2-carboxyethylgermanium(IV) sesquioxide) can be used as a precursor in the preparation of photoluminescent carbon dots, applicable as fluorescent probes in bioimaging applications.

Uses

antifungal and antiseptic

Definition

ChEBI: Propagermanium is an organogermanium compound.

brand name

Serosion

General Description

Bis(2-carboxyethylgermanium(IV) sesquioxide), also known as repagermanium, is a water-soluble organogermanium compound that exhibits immunostimulatory properties. It is also used as an ingredient in food and cosmetics.

Safety Profile

Moderately toxic by intravenous route. Experimental reproductive effects. See also GERMANIUM COMPOUNDS.

Carboxyethylgermanium sesquioxide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 201)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8753 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-81139210 +86-18192627656 1059@dideu.com China 3591 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5242 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20128 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 niki@zlchemi.com China 7245 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13620 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21599 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29833 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569262 +86-15003564040 1056@dideu.com China 3982 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9636 58

View Lastest Price from Carboxyethylgermanium sesquioxide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Carboxyethylgermanium sesquioxide pictures 2026-01-05 Carboxyethylgermanium sesquioxide
12758-40-6
US $10.00 / KG 100KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
Carboxyethylgermanium sesquioxide pictures 2026-01-05 Carboxyethylgermanium sesquioxide
12758-40-6
US $20.00-180.00 / G 5G 98% HPLC 1kg Shaanxi Dideu Medichem Co. Ltd
Bis(2-carboxyethylgermanium(IV) sesquioxide) pictures 2025-12-12 Bis(2-carboxyethylgermanium(IV) sesquioxide)
12758-40-6
US $0.00-0.00 / KG 1KG 99.9 1KG 100KG Shaanxi Dideu Medichem Co. Ltd
ORGANIC GERMANIUM CARBOXYETHYLGERMANIUM SESQUIOXIDE BIS(CARBOXYETHYLGERMANIUM SESQUIOXIDE) BIS-BETA CARBOXYETHYLGERMANIUM SESQUIOXIDE BETA-CARBOXYETHYLGERMANIUM OXIDE BETA-CARBOXYETHYLGERMANIUM SESQUIOXIDE BIS[2-CARBOXYETHYLGERMANIUM(IV)] SESQUIOXIDE BIS(2-CARBOXYETHYLGERMANIUM SESQUIOXIDE) GERMANIUM SESQUIOXIDE GE 132 3,3'-(1,3-DIOXO-1,3-DIGERMOXANEDIYL)BISPROPIONIC ACID 3,3-(1,3-dioxo-1,3-digermoxanediyl)-bispropionic REPAGERMANIUM 99.7% GERMANIUMSESQUIOXIDE,POWDER proxigermanium 1-PHENYL-2-CARBOXYLETHYLGERMANIUMSESQUISULPHIDE Bis(carboxyethylgermanium) sesquioxide, 99.7% 2-Carboxyethylgermanium sesquioxide 3,3'-(1,3-Dioxo-1,3-digermoxanediyl)dipropionic acid Germanium Sesquoxide Propanoic acid, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)bis Serocion 3-Oxygermylpropionic acid polymer SK-818 3,3'-(1,3-Dioxo-1,3-digerma-2-oxapropane-1,3-diyl)bispropionic acid 3,3'-(1,3-Dioxodigermoxane-1,3-diyl)dipropionic acid GerManiuM Sesquioxide USP Bis(2-carboxyethylgermanium(IV) sesquioxide), 99.5% organogermanium compound Bis[2-carboxyethylgermanium(IV)] Sesquioxide > Carboxyethylgermanium sesquioxide ISO 9001:2015 REACH Germanium Ge 132 Bis(2-carboxyethylgermanium(IV) sesquioxide),99.95% Dipropanoic acid germanium sequioxide β-Carboxyethylgermanium Sesquioxide 12758-40-6 OGeOCH2CH2CO2H2 C6H10O7Ge2 C6H10GeO7 Cell Signaling and Neuroscience Cell Biology BioChemical Ge (Germanium) Compounds Semimetal Compounds Classes of Metal Compounds Organometallic Reagents Others Organogermanium Immune Cell Signaling and Blood Immune System Regulation Immunomodulators and Antibiotics Nutritional Supplements Ge (Germanium) Compounds Classes of Metal Compounds Semimetal Compounds