L-Asparagine:H2O (2,3,3-d3, 94%)
- CAS No.
- 2483831-59-8
- Chemical Name:
- L-Asparagine:H2O (2,3,3-d3, 94%)
- Synonyms
- D3- L-Asparagine Hydrate;L-Asparagine·H?O (2,3,3-D?, 94%);L-Asparagine:H2O (2,3,3-d3, 94%);L-Asparagine-D3 Hydrate (Standard)
- CBNumber:
- CB22725831
- Molecular Formula:
- C4H10N2O4
- Molecular Weight:
- 150.13
- MDL Number:
- MFCD31814273
- MOL File:
- 2483831-59-8.mol
- MSDS File:
- SDS
L-Asparagine:H2O (2,3,3-d3, 94%) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 34835 | L-Asparagine-d3 (hydrate) ≥99%deuteratedforms(d1-d3) | 2483831-59-8 | 1mg | $41 | 2026-04-30 | Buy |
| Cayman Chemical | 34835 | L-Asparagine-d3 (hydrate) ≥99%deuteratedforms(d1-d3) | 2483831-59-8 | 5mg | $186 | 2026-04-30 | Buy |
| Cayman Chemical | 34835 | L-Asparagine-d3 (hydrate) ≥99%deuteratedforms(d1-d3) | 2483831-59-8 | 10mg | $293 | 2026-04-30 | Buy |
| ChemScene | CS-0311664 | L-Asparagine-d3 (hydrate) ≥98% | 2483831-59-8 | 1mg | $125 | 2026-06-04 | Buy |
| ChemScene | CS-0311664 | L-Asparagine-d3 (hydrate) ≥98% | 2483831-59-8 | 5mg | $401 | 2026-06-04 | Buy |
L-Asparagine:H2O (2,3,3-d3, 94%) Chemical Properties, Uses, Production
Uses
L-Asparagine-d3 (hydrate) is the deuterium labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
Biological Activity
L-Asparagine-d3 is intended for use as an internal standard for the quantification of L-asparagine by GC- or LC-MS. L-Asparagine is a non-essential amino acid.1 It is formed from L-aspartic acid and L-glutamine by asparagine synthetase (ASNS), and it is deamidated by L-asparaginase to produce L-aspartic acid and ammonia.2,3 L-Asparagine (0.3 mM) reverses ASNS siRNA knockdown-induced decreases in proliferation in a panel of six human cancer cell lines, indicating that both exogenous and endogenous L-asparagine promote proliferation of these cells.4 Formulations containing L-asparagine have been used as dietary supplements.
References
1.Chiu, M.I., Taurino, G., Bianchi, M.G., et al.Asparagine synthetase in cancer: Beyond acute lymphoblastic leukemiaFront. Oncol.91480(2020) 2.Zhu, W., Radadiya, A., Bisson, C., et al.High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivityCommun. Biol.2345(2019) 3.Covini, D., Tardito, S., Bussolati, O., et al.Expanding targets for a metabolic therapy of cancer: L-AsparaginaseRecent Pat. Anticancer Drug Discov.7(1)4-13(2012) 4.Pathria, G., Lee, J.S., Hasnis, E., et al.Translational reprogramming marks adaptation to asparagine restriction in cancerNat. Cell Biol.21(12)1590-1603(2019)
L-Asparagine:H2O (2,3,3-d3, 94%) Preparation Products And Raw materials
Raw materials
Preparation Products
L-Asparagine:H2O (2,3,3-d3, 94%) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TianJin Alta Scientific Co., Ltd. | 022-65378550-8551 | contact@altascientific.com | China | 2772 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| ChengDu SinoStandards Bio-Tech Co.,Ltd. ， | 028-83243028 19136088901 | sinostandards@163.com | China | 4979 | 58 |
| Reer Technology (Shanghai) Co., LTD | 021-64400900 15800436310 | bessey@reertech.com | China | 4097 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | offer.de@lgcgroup.com | China | 19036 | 58 |
| Shanghai Haohong Scientific Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 39319 | 58 |
| CHINA ISOTOPE CO., LIMITED | 02151600108 13062666369 | info@isotopechem.com | China | 4721 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 021-67187366 19901745723 | info@bwtlab.com | China | 9888 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | judy.xia@synzest.com | China | 12577 | 58 |
