ChemicalBook >> CAS DataBase List >>4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol

CAS No.
681482-81-5
Chemical Name:
4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol
Synonyms
Delamanid Impurity 4;Delamani intermediate;Delamanid Phenol Impurity;4-{4-[4-(Trifluoromethoxy)phenoxy]piperidino}benzenol;4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol;Phenol, 4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]-
CBNumber:
CB22734837
Molecular Formula:
C18H18F3NO3
Molecular Weight:
353.34
MDL Number:
MFCD16170437
MOL File:
681482-81-5.mol
Last updated:2025-07-14 15:27:00

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Properties

Melting point 113-114°C
Boiling point 461.2±45.0 °C(Predicted)
Density 1.308±0.06 g/cm3(Predicted)
storage temp. Refrigerator, under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka 12.25±0.30(Predicted)
form Solid
color Beige
InChI InChI=1S/C18H18F3NO3/c19-18(20,21)25-17-7-5-15(6-8-17)24-16-9-11-22(12-10-16)13-1-3-14(23)4-2-13/h1-8,16,23H,9-12H2
InChIKey KXHMPYHAQBAPJK-UHFFFAOYSA-N
SMILES C1(O)=CC=C(N2CCC(OC3=CC=C(OC(F)(F)F)C=C3)CC2)C=C1

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-T790895-5MG 4-[4-(4-Trifluoromethoxyphenoxy)piperidin-1-yl]phenol 681482-81-5 5mg $193 2026-06-03 Buy
TRC TRC-T790895-25MG 4-[4-(4-Trifluoromethoxyphenoxy)piperidin-1-yl]phenol 681482-81-5 25mg $734 2026-06-03 Buy
TRC TRC-T790895-100MG 4-[4-(4-Trifluoromethoxyphenoxy)piperidin-1-yl]phenol 681482-81-5 100mg $2180 2026-06-03 Buy
Matrix Scientific 169295 4-{4-[4-(Trifluoromethoxy)phenoxy]piperidino}benzenol 681482-81-5 500.00mg $918 2026-05-18 Buy
Matrix Scientific 169295 4-{4-[4-(Trifluoromethoxy)phenoxy]piperidino}benzenol 681482-81-5 1.00g $1836 2026-05-18 Buy
Product number Packaging Price Buy
TRC-T790895-5MG 5mg $193 Buy
TRC-T790895-25MG 25mg $734 Buy
TRC-T790895-100MG 100mg $2180 Buy
169295 500.00mg $918 Buy
169295 1.00g $1836 Buy

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Chemical Properties, Uses, Production

Uses

4-[4-(4-Trifluoromethoxyphenoxy)piperidin-1-yl]phenol is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Preparation Products And Raw materials

Raw materials

Preparation Products

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Suppliers

Global Suppliers ( 55)
Supplier Tel Email Country ProdList Advantage
Suzhou Haoyi Biotechnology Technology Co., Ltd. 15995756885 15995756885@139.com China 44 58
ZHIWE CHEMTECH CO LTD 021-20221225 13917446399 zwchem@163.com China 527 61
Pharmavoyager 15351203386 2592141051@qq.com China 93 55
Tongling HengYou Biotechnology Co., Ltd. 021-50426030 13856289449;13124863828 2630597085@qq.com China 1885 55
Taizhou Ruixin Chemical Co., Ltd. 0576-89085261 15867635987 jasonhu09@163.com China 439 50
ShangHai Angti Biotechnology Co., Ltd. 13764913901 info@angtibio.com China 4976 55
TaiChem Taizhou Limited 052386810091 zcwy9518@yeah.net China 3917 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4578 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@yongstandards.com China 9995 55

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Spectrum

4-[4-[4-(trifluoroMethoxy)phenoxy]piperidin-1-yl]phenol Phenol, 4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]- 4-{4-[4-(Trifluoromethoxy)phenoxy]piperidino}benzenol Delamanid Phenol Impurity Delamani intermediate Delamanid Impurity 4 681482-81-5