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Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate

Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate Structure
Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate structure
CAS No.
909422-39-5
Chemical Name:
Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate
Synonyms
Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate;tert-Butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate;tert-butyl 4-[3-(hydroxymethyl)phenyl]piperidine-1-carboxylate - [B87852];1-Piperidinecarboxylic acid, 4-[3-(hydroxymethyl)phenyl]-, 1,1-dimethylethyl ester
CBNumber:
CB23060951
Molecular Formula:
C17H25NO3
Molecular Weight:
291.39
MDL Number:
MFCD30099260
MOL File:
909422-39-5.mol
MSDS File:
SDS
Last updated:2026-05-28 00:08:58
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Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate Properties

Boiling point 426.0±40.0 °C(Predicted)
Density 1.109±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 14.36±0.10(Predicted)
form powder
InChIKey OWDXAWCQYCRTIR-UHFFFAOYSA-N
SMILES O=C(N(CC1)CCC1C2=CC(CO)=CC=C2)OC(C)(C)C
UNSPSC Code 12352116
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
Signal word  Warning
Hazard statements  H315-H317-H319-H410
Precautionary statements  P261-P264-P273-P280-P302+P352-P305+P351+P338
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
Hazard Classifications Aquatic Acute 1
Aquatic Chronic 1
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1

Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Synthonix B87852 tert-butyl 4-[3-(hydroxymethyl)phenyl]piperidine-1-carboxylate 97% 909422-39-5 100mg $310 2026-05-06 Buy
Synthonix B87852 tert-butyl 4-[3-(hydroxymethyl)phenyl]piperidine-1-carboxylate 97% 909422-39-5 250mg $500 2026-05-06 Buy
Synthonix B87852 tert-butyl 4-[3-(hydroxymethyl)phenyl]piperidine-1-carboxylate 97% 909422-39-5 500mg $830 2026-05-06 Buy
Synthonix B87852 tert-butyl 4-[3-(hydroxymethyl)phenyl]piperidine-1-carboxylate 97% 909422-39-5 1g $1250 2026-05-06 Buy
Synthonix B87852 tert-butyl 4-[3-(hydroxymethyl)phenyl]piperidine-1-carboxylate 97% 909422-39-5 5g $3740 2026-05-06 Buy
Product number Packaging Price Buy
B87852 100mg $310 Buy
B87852 250mg $500 Buy
B87852 500mg $830 Buy
B87852 1g $1250 Buy
B87852 5g $3740 Buy

Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate Chemical Properties, Uses, Production

Uses

tert-Butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.

reaction suitability

reagent type: linker

Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
TaiChem Taizhou Limited 052386810091 zcwy9518@yeah.net China 3917 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49299 58
PharmaBlock Sciences (Nanjing), Inc. 4000255188 sales@pharmablock.com China 7266 58
tianjinlinchenkejiyouxiangongsi 15122256084 15122256084 zhujianlin01@163.com China 3028 58
Suzhou ARTK Medchem Co., Ltd. +86-18168183658 sales1@artkmedchem.com China 39007 58
HANGZHOU LEAP CHEM CO., LTD. +86-571-87711850 +86-15355479329 market18@leapchem.com China 43303 58
Supplier Advantage
PharmaBlock Sciences (Nanjing),Inc. 55
TaiChem Taizhou Limited 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58
PharmaBlock Sciences (Nanjing), Inc. 58
tianjinlinchenkejiyouxiangongsi 58
Suzhou ARTK Medchem Co., Ltd. 58
HANGZHOU LEAP CHEM CO., LTD. 58

Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate Spectrum

Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate(909422-39-5)1HNMR

909422-39-5 (Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate) Related Search:

1853217-57-8 tert-butyl 4-(3-(2-aminoethyl)phenyl)piperidine-1-carboxylate tert-butyl 4-(3-(aminomethyl)phenyl)piperidine-1-carboxylate hydrochloride tert-butyl 4-(4-(2-hydroxyethyl)phenyl)piperidine-1-carboxylate tert-butyl 4-(4-(hydroxymethyl)phenyl)piperidine-1-carboxylate
tert-Butyl 4-(4-(aminomethyl)phenyl)piperidine-1-carboxylate Tert-butyl 4-(2-(2-hydroxyethyl)phenyl)piperidine-1-carboxylate tert-butyl 4-(4-(2-aminoethyl)phenyl)piperidine-1-carboxylate

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Tert-butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate 1-Piperidinecarboxylic acid, 4-[3-(hydroxymethyl)phenyl]-, 1,1-dimethylethyl ester tert-Butyl 4-(3-(hydroxymethyl)phenyl)piperidine-1-carboxylate tert-butyl 4-[3-(hydroxymethyl)phenyl]piperidine-1-carboxylate - [B87852] 909422-39-5