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3,4-Dimethoxycinnamonitrile

CAS No.
6443-72-7
Chemical Name:
3,4-Dimethoxycinnamonitrile
Synonyms
Cinnamonitrile, 3,4-dimethoxy-;NSC 51968;Donepezil Impurity 67;Donepezil Intermediate 21;3,4-DIMETHOXYCINNAMONITRILE;3,4- twoMethoxy cinnaMic acid;3-(3,4-Dimethoxyphenyl)acrylonitrile;β-(3,4-Dimethoxyphenyl)acrylonitrile;cis/trans-3,4-Dimethoxycinnamonitrile;3-(3,4-Dimethoxyphenyl)-2-propenenitrile
CBNumber:
CB2311940
Molecular Formula:
C11H11NO2
Molecular Weight:
189.21
MDL Number:
MFCD00001931
MOL File:
6443-72-7.mol
MSDS File:
SDS
Last updated:2026-05-28 00:15:19

3,4-Dimethoxycinnamonitrile Properties

Melting point 181-184C
Boiling point 324.47°C (rough estimate)
Density 1.1596 (rough estimate)
refractive index 1.5012 (estimate)
InChI 1S/C11H11NO2/c1-13-10-6-5-9(4-3-7-12)8-11(10)14-2/h3-6,8H,1-2H3/b4-3+
InChIKey WGPTVEZJYRFEGT-ONEGZZNKSA-N
SMILES COc1ccc(\C=C\C#N)cc1OC
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P280
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  36-36/37/39-26-24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29269090
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
NFPA 704
0
2 0

3,4-Dimethoxycinnamonitrile price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 145343 3,4-Dimethoxycinnamonitrile, predominantly trans 97% 6443-72-7 1g $79.9 2023-06-20 Buy
Usbiological 274260 3,4-Dimethoxycinnamonitrile, predominantly trans Asreported 6443-72-7 1g $399 2026-06-03 Buy
Usbiological 274260 3,4-Dimethoxycinnamonitrile, predominantly trans Asreported 6443-72-7 2g $609 2026-06-03 Buy
Usbiological 274260 3,4-Dimethoxycinnamonitrile, predominantly trans Asreported 6443-72-7 5g $861 2026-06-03 Buy
Usbiological 232253 3,4-Dimethoxycinnamonitrile, predominantly trans ≥97% 97% 6443-72-7 1g $200 2026-06-03 Buy
Product number Packaging Price Buy
145343 1g $79.9 Buy
274260 1g $399 Buy
274260 2g $609 Buy
274260 5g $861 Buy
232253 1g $200 Buy

3,4-Dimethoxycinnamonitrile Chemical Properties,Uses,Production

Chemical Properties

Clear yellow liquid

Uses

3,4-Dimethoxycinnamonitrile undergoes condensation with ethyl glycollate to yield 2-(3,4-dimethoxyphenyl)-3-cyanotetrahydrofuran-4-one.

General Description

3,4-Dimethoxycinnamonitrile undergoes condensation with ethyl glycollate to yield 2-(3,4-dimethoxyphenyl)-3-cyanotetrahydrofuran-4-one.

3,4-Dimethoxycinnamonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 136)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Beijing dtftchem Technology Co., Ltd. 010-60275820 13031183356 elainezt@sina.com China 1386 62
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6746 52
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 22497 55
Credit-Chem Co., Ltd. 400-821-5857 021-64326257 credit-chem@foxmail.com China 5212 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9883 50
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Nanjing Abix Biochemical Technology Co., Ltd. 025-87193546 18652950785; chemweiao@163.com China 9009 60
ShangHai Siyan Biological Technology Co., Ltd. 021-50908862,442785678,326799392 18721037013 siyansales@126.com China 9612 58

View Lastest Price from 3,4-Dimethoxycinnamonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,4-Dimethoxycinnamonitrile pictures 2026-03-20 3,4-Dimethoxycinnamonitrile
6443-72-7
1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
3,4-Dimethoxycinnamonitrile pictures 2019-07-06 3,4-Dimethoxycinnamonitrile
6443-72-7
$2.00 1 kg 99% Career Henan Chemical Co
3-(3,4-Dimethoxyphenyl)acrylonitrile 3,4-DIMETHOXYCINNAMONITRILE Donepezil Intermediate 21 (E)-3-(3,4-dimethoxyphenyl)-2-propenenitrile 3,4- twoMethoxy cinnaMic acid 3,4-Dimethoxycinnamonitrile, predominantly trans 97% (E)-3-(3,4-Dimethoxyphenyl)prop-2-enenitrile 2-Propenenitrile, 3-(3,4-dimethoxyphenyl)- Cinnamonitrile, 3,4-dimethoxy- 3,4-DIMETHOXYCINNAMONITRILE, 97%, MIXTURE OF CIS AND TRANS (2E)-3-(3,4-dimethoxyphenyl)acrylonitrile 3-(3,4-Dimethoxyphenyl)-2-propenenitrile β-(3,4-Dimethoxyphenyl)acrylonitrile 3,4-Dimethoxycinnamonitrile, mixture of cis and trans 3,4-DIMETHOXYCINNAMONITRILE, 97%, PREDOM INANTLY TRANS cis/trans-3,4-Dimethoxycinnamonitrile 3,4-dimethoxycinnamonitrile, predominantly trans Donepezil Impurity 67 NSC 51968 3,4-Dimethoxycinnamonitrile, predominantly trans 6443-72-7 CH3O2C6H3CHCHCN Building Blocks C10 to C27 Organic Building Blocks Nitrogen Compounds Cyanides/Nitriles C10 to C27 Cyanides/Nitriles Nitrogen Compounds