ChemicalBook >> CAS DataBase List >>GSK 461364 analogue I
GSK 461364 analogue I
- CAS No.
- 929095-23-8
- Chemical Name:
- GSK 461364 analogue I
- Synonyms
- GSK579289A;GSK 461364 analogue I;2-Thiophenecarboxamide, 3-[(1R)-1-(2-chlorophenyl)ethoxy]-5-[6-[(1-methyl-4-piperidinyl)oxy]-1H-benzimidazol-1-yl]-
- CBNumber:
- CB23146299
- Molecular Formula:
- C26H27ClN4O3S
- Molecular Weight:
- 511.04
- MDL Number:
- MFCD18089836
- MOL File:
- 929095-23-8.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
GSK 461364 analogue I price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | EMB09523 | GSK 461364 analogue I | 929095-23-8 | 25mg | $1207.25 | 2026-06-04 | Buy |
| Biosynth | EMB09523 | GSK 461364 analogue I | 929095-23-8 | 50mg | $1679 | 2026-06-04 | Buy |
| Biosynth | EMB09523 | GSK 461364 analogue I | 929095-23-8 | 100mg | $2687 | 2026-06-04 | Buy |
| Axon Medchem | Axon1625 | GSK579289A 99% | 2mg | $121 | 2026-05-19 | Buy | |
| Axon Medchem | Axon1625 | GSK579289A 99% | 5mg | $198 | 2026-05-19 | Buy |
GSK 461364 analogue I Chemical Properties, Uses, Production
Biological Activity
GSK579289A is an inhibitor of polo-like kinase 1 (Plk1; IC50 = 2 nM).1 It is selective for Plk1 over Plk3 (IC50 = 630 nM). GSK579289A inhibits proliferation of HCT116 cells (IC50 = 11 nM).
References
1.Rheault, T.R., Donaldson, K.H., Badiang-Alberti, J.G., et al.Heteroaryl-linked 5-(1H-benzimidazol-1-yl)-2-thiophenecarboxamides: Potent inhibitors of polo-like kinase 1 (PLK1) with improved drug-like propertiesBioorg. Med. Chem. Lett.20(15)4587-4592(2010)
GSK 461364 analogue I Preparation Products And Raw materials
Raw materials
Preparation Products
GSK 461364 analogue I Suppliers
Global Suppliers ( 11)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4999 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1246 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
GSK 461364 analogue I
GSK579289A
2-Thiophenecarboxamide, 3-[(1R)-1-(2-chlorophenyl)ethoxy]-5-[6-[(1-methyl-4-piperidinyl)oxy]-1H-benzimidazol-1-yl]-
929095-23-8
