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ChemicalBook >> CAS DataBase List >>(1R,2S,3S)-Aprepitant

(1R,2S,3S)-Aprepitant

(1R,2S,3S)-Aprepitant Structure
(1R,2S,3S)-Aprepitant structure
CAS No.
172822-28-5
Chemical Name:
(1R,2S,3S)-Aprepitant
Synonyms
SM001F;(2S,3S,1’R)-Aprepitant;Aretetan Impurity-(RSS);Aprepitant (R,S,S)-Isomer;Aprepitant Impurity - (RSS);(R,S,S)-Enantiomer Aprepitant;Aprepitant Impurity 6(R,S,S-Isomer);Aprepitant Intermediate Impurity -(RSS);Aprepitant impurity 7/(1R,2S,3S)-Aprepitant;5-([(2S,3S)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one
CBNumber:
CB23146512
Molecular Formula:
C23H21F7N4O3
Molecular Weight:
534.43
MDL Number:
MOL File:
172822-28-5.mol
Last updated:2024-06-11 18:14:38
Product description Number Pack Size Price
(2S,3S,1’R)-Aprepitant 421992 1mg $523
(2S,3S,1’R)-Aprepitant AA01E2OH 50mg $837
(2S,3S,1’R)-Aprepitant AA01E2OH 100mg $1099
(2S,3S,1’R)-Aprepitant A729770 25mg $2365
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(1R,2S,3S)-Aprepitant Properties

Density 1.51±0.1 g/cm3(Predicted)
pka 8.06±0.20(Predicted)

(1R,2S,3S)-Aprepitant price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 421992 (2S,3S,1’R)-Aprepitant 172822-28-5 1mg $523 2026-06-03 Buy
aablocks AA01E2OH (2S,3S,1’R)-Aprepitant 172822-28-5 50mg $837 2026-05-30 Buy
aablocks AA01E2OH (2S,3S,1’R)-Aprepitant 172822-28-5 100mg $1099 2026-05-30 Buy
TRC A729770 (2S,3S,1’R)-Aprepitant 172822-28-5 25mg $2365 2021-12-16 Buy
Product number Packaging Price Buy
421992 1mg $523 Buy
AA01E2OH 50mg $837 Buy
AA01E2OH 100mg $1099 Buy
A729770 25mg $2365 Buy

(1R,2S,3S)-Aprepitant Chemical Properties,Uses,Production

Uses

(2S,3S,1’R)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic. (2S,3S,1’R)-Aprepitant is also a useful synthetic intermediate in the synthesis of morpholine tachykinin receptor antagonist prodrugs.

(1R,2S,3S)-Aprepitant Preparation Products And Raw materials

Raw materials

Preparation Products

(1R,2S,3S)-Aprepitant Suppliers

Global( 44)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14320 58
ANHUI WITOP BIOTECH CO., LTD 		+8618071025641 eric@witopchemical.com China 23506 58
BOC Sciences 		16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
CR Corporation Limited 		fred.wen@crcorporation.cn China 8642 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		+86-18627948422 sale@hdimpurity.com China 3676 58
Moxin Chemicals 		+86-17320513646 +86-17320513646 anna@molcoo.com China 9998 58
Pure Research Chemicals 		+86-13564847951 +86-18019592524 info@purerechem.com China 1000 58
Sinco Pharmachem (ShenZhen) R&D Co., Ltd. 		+86-18603013401 jack.lin@sincopharmachem.com China 9999 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131885 58
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Supplier Advantage
Standardpharm Co. Ltd. 		58
ANHUI WITOP BIOTECH CO., LTD 		58
BOC Sciences 		58
CR Corporation Limited 		58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		58
Moxin Chemicals 		58
Pure Research Chemicals 		58
Sinco Pharmachem (ShenZhen) R&D Co., Ltd. 		58
Amadis Chemical Company Limited 		58
Quality Control Solutions Ltd. 56

View Lastest Price from (1R,2S,3S)-Aprepitant manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Aprepitant Impurity 22 pictures 2026-03-12 Aprepitant Impurity 22
172822-28-5
 10mg 98% 500mg ShenZhen H&D Pharmaceutical Technology Co., LTD

172822-28-5((1R,2S,3S)-Aprepitant)Related Search:

Aprepitant 5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol Benzyl dihydrogen phosphate (2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride
Aprepitant Impurity 19 [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine Fosaprepitant Impurity 6 Aprepitant ent-Aprepitant
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Aprepitant 1,1,1-Trimethoxy-2-chloroethane Aprepitant Defluoro Aprepitant
Aprepitant Impurity B HCl Aprepitant Impurity 11 HCl Aprepitant Impurity 2

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Aprepitant Impurity - (RSS) Aprepitant Intermediate Impurity -(RSS) Aprepitant impurity 7/(1R,2S,3S)-Aprepitant Aprepitant Impurity 6(R,S,S-Isomer) (R,S,S)-Enantiomer Aprepitant Aprepitant (R,S,S)-Isomer Aretetan Impurity-(RSS) 5-([(2S,3S)-2-((R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one 3H-1,2,4-Triazol-3-one, 5-[[2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-, [2S-[2α(S*),3β]]- (9CI) SM001F (2S,3S,1’R)-Aprepitant 3H-1,2,4-Triazol-3-one, 5-[[(2S,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro- 172822-28-5