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N,N'-DICYCLOHEXYLUREA

CAS No.
2387-23-7
Chemical Name:
N,N'-DICYCLOHEXYLUREA
Synonyms
1,3-DICYCLOHEXYLUREA;Indapamide Impurity 1;Dicyclohexylcarbodiamide;NSC 30023;NSC 17013;AURORA KA-3582;Lomustine USP RC C;Lomustine Impurity C;N,N'-DICYCLOHEXYLUREA;n,n’-dicyclohexyl-ure
CBNumber:
CB2314754
Molecular Formula:
C13H24N2O
Molecular Weight:
224.34
MDL Number:
MFCD00003829
MOL File:
2387-23-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:28:30
Product description Number Pack Size Price
Lomustine Related Compound C certified reference material, pharmaceutical secondary standard PHR2924 500MG $667
N,N′-Dicyclohexylurea 98% D80800 25g $153
Lomustine Related Compound C United States Pharmacopeia (USP) Reference Standard 1369442 25mg $1410
1,3-Dicyclohexylurea >98.0%(GC)(T) D0441 25g $35
1,3-Dicyclohexylurea >98.0%(GC)(T) D0441 500g $260
More product size

N,N'-DICYCLOHEXYLUREA Properties

Melting point 232-233 °C(lit.)
Boiling point 408℃
Density 1.02
refractive index 1.4832 (estimate)
Flash point 158℃
storage temp. 2-8°C
solubility DMSO (Slightly, Heated), Methanol (Slightly)
form Liquid
pka 13.89±0.20(Predicted)
color Clear
Stability Hygroscopic
InChI InChI=1S/C13H24N2O/c16-13(14-11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h11-12H,1-10H2,(H2,14,15,16)
InChIKey ADFXKUOMJKEIND-UHFFFAOYSA-N
SMILES N(C1CCCCC1)C(NC1CCCCC1)=O
CAS DataBase Reference 2387-23-7(CAS DataBase Reference)
FDA UNII ZV7823VVIM
EPA Substance Registry System N,N'-Dicyclohexylurea (2387-23-7)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,N
Risk Statements  22-51/53
Safety Statements  61
WGK Germany  3
TSCA  TSCA listed
HS Code  29242100
Storage Class 11 - Combustible Solids
NFPA 704
1
0 0

N,N'-DICYCLOHEXYLUREA price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2924 Lomustine Related Compound C certified reference material, pharmaceutical secondary standard 2387-23-7 500MG $667 2026-04-30 Buy
Sigma-Aldrich D80800 N,N′-Dicyclohexylurea 98% 2387-23-7 25g $153 2026-04-30 Buy
Sigma-Aldrich 1369442 Lomustine Related Compound C United States Pharmacopeia (USP) Reference Standard 2387-23-7 25mg $1410 2026-04-30 Buy
TCI Chemical D0441 1,3-Dicyclohexylurea >98.0%(GC)(T) 2387-23-7 25g $35 2026-04-30 Buy
TCI Chemical D0441 1,3-Dicyclohexylurea >98.0%(GC)(T) 2387-23-7 500g $260 2026-04-30 Buy
Product number Packaging Price Buy
PHR2924 500MG $667 Buy
D80800 25g $153 Buy
1369442 25mg $1410 Buy
D0441 25g $35 Buy
D0441 500g $260 Buy

N,N'-DICYCLOHEXYLUREA Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

N,N''-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C.

Definition

ChEBI: 1,3-dicyclohexylurea is a member of ureas.

Preparation

An excess of dry ice (200 g) was added gradually to a solution of dicyclohexylcarbodiimide (2.06 g, 0.01 mol), cyclohexylamine (1.98 g, 0.02 mol), and triethylamine (2.2 g, 0.02 mol) in THF at 75 ℃ over a period of 8 h. After stirring for 8 h, the reaction mixture was concentrated under reduced pressure and the resultant precipitate was collected. Fractional recrystallization of the precipitate from acetone/methanol gave N,N'-dicyclohexylurea; yield 2.2 g (98% based on dicyclohexylcarbodiimide and cyclohexylamine).

Synthesis Reference(s)

The Journal of Organic Chemistry, 61, p. 4175, 1996 DOI: 10.1021/jo9522825

108-91-8
57-13-6
2387-23-7
Synthesis of N,N'-DICYCLOHEXYLUREA from Cyclohexylamine and Urea
Global( 268)Suppliers
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Hubei Lidu New Material Technology Co., Ltd
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View Lastest Price from N,N'-DICYCLOHEXYLUREA manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N,N`-DICYCLOHEXYLUREA pictures 2026-05-26 N,N`-DICYCLOHEXYLUREA
2387-23-7
US $0.00 / g 1g 97% 20tons Hubei Lidu New Material Technology Co., Ltd
N,N'-Dicyclohexylurea pictures 2026-05-11 N,N'-Dicyclohexylurea
2387-23-7
US $39.00-53.00 / mg ≥98% 10g TargetMol Chemicals Inc.
Lomustine EP impurity C pictures 2025-12-19 Lomustine EP impurity C
2387-23-7
US $0.00-0.00 / mg 5mg 95%+ 1000mg Guangzhou Tosun Pharmaceutical Ltd
AURORA KA-3582 n,n’-dicyclohexyl-ure N,N'-DICYCLOHEXYLUREA N,N,-Dicyclohexylurea98.% Dicyclohexylcarbodiamide N,N'-Carbonylbis(cyclohexanamine) NSC 17013 NSC 30023 LoMustine Related CoMpound C Lomustine EP Impurity B 5-cyanobenzene-1,3-dicarboxylic acid 1,3-Dicyclohexylurea for synthesis Indapamide Impurity 1 1,3-Dicyclohexylurea > Lomustine USP RC C Urea, N,N'-dicyclohexyl- Lomustine Related Compound C (1,3-Dicyclohexylurea) (1369442) Lomustine Impurity C Lomustine EP Impurity C Lomustine USP Related Compound C Lomustine Impurity 3(Lomustine EP Impurity C)(Lomustine USP RC C) 1,3-Dicyclohexylurea, ≥ 98.0% n,n''-dicyclohexylurea 1,3-dicyclohexylurea - impurity N,N''-Dicyclohexylurea, 10 mM in DMSO N,N′-Dicyclohexylurea N,N′-Dicyclohexylurea, CAS 2387-23-7 1,3-Dicyclohexylurea - [D94419] Lomustine Impurity 3 (Lomustine EP Impurity C)(Lomustine USP Related Compound C) Lomustine EP Impurity C (Lomustine USP Related Compound C) 1,3-DICYCLOHEXYLUREA 2387-23-7 C13H24N2O C6H11NHCONHC6H11 Organic Building Blocks Ureas Building Blocks Carbonyl Compounds Finasteride Carbonyl Compounds Organic Building Blocks Ureas