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10-Deacetylbaccatin III

10-Deacetylbaccatin III structure

CAS No.: 32981-86-5

Chemical Name:: 10-Deacetylbaccatin III

Synonyms: 10-DAB;10-DEACETYLBACCATIN;10-DAB Ⅲ;10-DAB-III;1-Deacetylbaccatin III;Docetaxel EP Impurity E;10-Deacetyl Baccatin lll;ó;NH24841;10DBA III

CBNumber:: CB3447497

Molecular Formula:: C29H36O10

Molecular Weight:: 544.59

MDL Number:: MFCD00132913

MOL File:: 32981-86-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-07 16:53:29

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10-Deacetylbaccatin III Properties

Melting point	231-236 °C
alpha	-44.5 º (c=1, methanol 25 ºC)
Boiling point	717℃
Density	1.2007 (rough estimate)
refractive index	1.5376 (estimate)
Flash point	>110°(230°F)
storage temp.	Sealed in dry,Room Temperature
solubility	methanol: soluble, clear, colorless (5 mg + 0.1 mL MeOH)
pka	11.50±0.70(Predicted)
form	Powder
color	white
Water Solubility	INSOLUBLE
InChIKey	YWLXLRUDGLRYDR-IYNRKYTHSA-N
SMILES	O1C[C@@]2(OC(C)=O)[C@@]3([H])[C@H](OC(=O)C4=CC=CC=C4)[C@@]4(O)C(C)(C)C(=C(C)[C@@H](O)C4)[C@@H](O)C(=O)[C@]3(C)[C@@H](O)C[C@@]12[H]
LogP	0.156 (est)
CAS DataBase Reference	32981-86-5(CAS DataBase Reference)
FDA UNII	4K6EWW2Z45
UNSPSC Code	51102829
NACRES	NA.85

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Danger

Hazard statements

H315-H319-H335-H340-H350-H373

Precautionary statements

P201-P302+P352-P305+P351+P338-P308+P313

target organs

Respiratory system

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Risk Statements

23/24/25

Safety Statements

45-38-36/37/39-28A-24/25

RIDADR

1544

WGK Germany

HazardClass

6.1(b)

PackingGroup

III

HS Code

29329990

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Carc. 1B
Eye Irrit. 2
Muta. 1B
Skin Irrit. 2
STOT RE 2
STOT SE 3

REACH Registrations

Active

NFPA 704

	0
4		0

10-Deacetylbaccatin III price More Price(68)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0001452	Docetaxel impurity E European Pharmacopoeia (EP) Reference Standard	32981-86-5	15 mg	$127	2026-04-30	Buy
Sigma-Aldrich	PHR3007	10-desacetyl-baccatin III pharmaceutical secondary standard, certified reference material	32981-86-5	50 mg	$640	2026-04-30	Buy
Sigma-Aldrich	D3676	10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC)	32981-86-5	5mg	$407	2026-04-30	Buy
Sigma-Aldrich	D3676	10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC)	32981-86-5	1mg	$108	2023-06-20	Buy
TCI Chemical	D4148	10-Deacetylbaccatin III >98.0%(HPLC)	32981-86-5	100mg	$92	2026-04-30	Buy

Product number	Packaging	Price	Buy
Y0001452	15 mg	$127	Buy
PHR3007	50 mg	$640	Buy
D3676	5mg	$407	Buy
D3676	1mg	$108	Buy
D4148	100mg	$92	Buy

10-Deacetylbaccatin III Chemical Properties, Uses, Production

Chemical Properties

10-Deacetylbaccatin III is White Solid

Uses

10-DAB (10-Deacetylbaccatin) is an antineoplastic agent and an anti-cancer intermediate. 10-DAB (10-Deacetylbaccatin) has gained great attention because of its partly excellent anti-cancer properties. 10-DAB (10-Deacetylbaccatin) can be gained from the le

Uses

10-Deacetyl Baccatin III is an impurity of Paclitaxel (P132500) and derivatives.

Uses

10-Deacetylbaccatin III is a intermediate in the synthesis of Taxol and derivatives

Definition

ChEBI: 10-deacetylbaccatin III is a tetracyclic diterpenoid and a secondary alpha-hydroxy ketone. It is functionally related to a baccatin III.

General Description

10-Deacetylbaccatin III, also known as Paclitaxel Impurity 19, is an impurity of Paclitaxel. Paclitaxel is a chemotherapy drug. Chemotherapy is a treatment that destroys cancer cells using anti-cancer drugs. Paclitaxel is the non-branded name of the drug, but you may hear it called by one of its brand names such as Taxol. Some people are given a drug called nab-paclitaxel (Abraxane).

Biological Activity

10-dab (also known as 10-deacetylbaccatin) is an intermediate used for the preparation of taxol, an anti-leukemic and tumor-inhibiting agent isolated from the inner bark of the pacific yew tree taxus brevifolia as well as other species of the genus taxus. due to the low availability of taxol from its natural sources, 10-dab is used as a raw material for the preparation of taxol and its derivatives. being easily extracted from the annual cute of the yew leaves, 10-dab has a very folded chemical structure with the α hydroxyl group hindered at c-13 easily to form a hydrogen bond with the 4α acetyl group.f. gueritte-voegelein, v. senilh, b. david, d. guenard and p. potier. chemical studies of 10-deacetyl baccatin iii hemisynthesis of taxol derivatives. tetrahedron 1986; 42(16): 4451-4460

10-Deacetylbaccatin III synthesis

Synthesis of 10-Deacetylbaccatin III from Acetylbaccatin III, 7-(P)

10-Deacetylbaccatin III Preparation Products And Raw materials

Raw materials

Preparation Products

7,10-Dimethoxy-10-DAB III

10-Deacetylbaccatin III Suppliers

Global Suppliers ( 672)

Supplier	Tel	Email	Country	ProdList	Advantage
ShangHai YuanYe Biotechnology Co., Ltd.	15026964105	shyysw007@163.com	China	4998	60
Wuhu Nuowei Chemical Technology Co., Ltd	0553-8233716 18055326116	sales@nuowei-chem.com	China	361	58
Suzhou Gopon Pharmaceutical Co., Ltd	13358059751	gopon2012@gmail.com	China	285	58
Nanjing jingzhu bio-technology Co.,Ltd	025-52794219 13140719234	2498234449@qq.com	China	124	58
Chengdu Gupte Biotechnology Co., Ltd.	13881890404	2851503757@qq.com	China	2283	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
ZHIWE CHEMTECH CO LTD	021-20221225 13917446399	zwchem@163.com	China	524	61

Supplier	Advantage
ShangHai YuanYe Biotechnology Co., Ltd.	60
Wuhu Nuowei Chemical Technology Co., Ltd	58
Suzhou Gopon Pharmaceutical Co., Ltd	58
Nanjing jingzhu bio-technology Co.,Ltd	58
Chengdu Gupte Biotechnology Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
INTATRADE GmbH	66
3B Pharmachem (Wuhan) International Co.,Ltd.	69
ZHIWE CHEMTECH CO LTD	61

View Latest Price from 10-Deacetylbaccatin III manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-02	10-Deacetylbaccatin III 32981-86-5	$1.40-35.00	1kg	99%		Henan Fengda Chemical Co., Ltd
2026-08-12	10-Deacetylbaccatin III 32981-86-5	$6666.00	2KG	99	100kg	Baoji Guokang Healthchem Co., Ltd.
2026-07-07	10-Deacetylbaccatin III 32981-86-5	$29.00		99.91%	10g	TargetMol Chemicals Inc.

10-Deacetylbaccatin III
32981-86-5
$1.40-35.00
99%
Henan Fengda Chemical Co., Ltd

10-Deacetylbaccatin III
32981-86-5
$6666.00
99
Baoji Guokang Healthchem Co., Ltd.

10-Deacetylbaccatin III
32981-86-5
$29.00
99.91%
TargetMol Chemicals Inc.

10-Deacetylbaccatin III Spectrum

10-Deacetylbaccatin III(32981-86-5)¹HNMR

32981-86-5 (10-Deacetylbaccatin III) Related Search:

Baccatine III Acetylferrocene Acetylacetone (2R,3S)-N-Benzoyl-3-phenyl Isoserine N-Acetyl-L-tyrosine ethyl ester

Docetaxel Docetaxel Impurity 36 Docetaxel impurity 1/(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-6,9,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(((2,2,2-trichloroethoxy)carbonyl)oxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl Docetaxel Impurity 5 2-Debenzoyl-2-pentenoyl Docetaxel

13-O-(Triethylsilyl) Baccatin III 10-Oxo Docetaxel Docetaxel Metabolite M4 (2S,3S)-methyl 3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropanoate HLCSYHHJEMPKSY-RRKHLBDSSA-N

4-Dichloroethoxy-carbonyl docetaxel 2-Azetidinone, 3-hydroxy-4-phenyl-1-[(1S)-1-phenylethyl]-, (3R,4S)- Docetaxel Impurity 15

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10-Deacetyl Baccatin lll Deacetylbaccatin III 10-deacetylbaccatin11 10-deacetylbaccatiniii(extaxusbaccata) 10-DEACETYLBACCATIN III FROMTAXUS BACCAT A 10-Dab98.5% 10-Deacetylbaccatine(III) 10-Deacetyl Baccatin ¢ 10-Deacetylbaccatine 10-DAB III(10-DEACETYL BACCATIN III) 99% DEACETYLBACCATIN-III, 10(P) 10-DAB(10-deacetylbaccatin) 10-Deacetyl DESACETYLBACCATINE BACCATIN III, 10-DEACETYL- 10-Deacetylbaccatin III 10-O-DEACETYLBACCATIN III high quality 10-deacetylbacctin Ⅲ(10-DAB) CAS 32981-86-5 CAS NO.32981-86-5 10-Deacetylbaccatin III 32981-86-5 Paclitaxel Impurity 19 Docetaxel EP impurity E，10-desacetyl-baccatin III 10-Deacetylbacatin III Docetaxel IMpurity E (10-Deacetyl Baccatin III) ó 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)- Docetaxel impurity E 10-Deacetylbaccatin III, >=99% 10-deacetyl Chiba Cardin Ⅲ 12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3 (2AR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl- 10-DEACETYLBACCATIN III (EX TAXUS BACCATA), CONTAINS CA 0.5 MOLE OF METHANOL 95% 10-DEACETYL BACCATIN (10-DAB ) 10-Desacetylbaccatin III 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one,12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-,[2aR-(2aα,4β,4aβ,6β,9α,11α,12α,12aα,12bα)]- 12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one 10-DEACETYLBACCATIN III, 95%, FROM TAXUS BACCATA 10-Deacetyl Baccatin ￠ó 12b-(Acetyloxy)-12-(Benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-Dodecahydro-4,6,9,11-Tetrahydroxy-4a,8,13,13-Tetramethyl-7,11-Methano-5h-Cyclodeca[3,4] 10-Deacetylbaccatin III ,97% 10-DAB Ⅲ 10-Decaacetyl baccatin III 10DBA III 10-Deacetyl baccatine IIII 10-Deacetylbaccatin Ⅲ(10-DAB) 5β,20-Epoxy-4-(acetyloxy)-1,7β,10β,13α-tetrahydroxy-9-oxotax-11-en-2α-yl benzoate (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetraMethyl-7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one Docetaxel Impurity 5(Docetaxel EP Impurity E) NH24841 10-DAB：10-Deacetylbaccatin III Docetaxel EP Impurity E (10-Deacetyl Baccatin III) 10-DeacetylbaccatinIII> Docetaxel impurity E CRS 3-(5-chloro-2-fluorobenzyl)isonicotinic acid 10-Deacetylbaccatin III USP/EP/BP 10-Deacetylbaccatin IIIQ: What is 10-Deacetylbaccatin III Q: What is the CAS Number of 10-Deacetylbaccatin III Q: What is the storage condition of 10-Deacetylbaccatin III Q: What are the applications of 10-Deacetylbaccatin III 10-Deacetylbaccatin III, 95%, Paclitaxel Impurity 29 (See C4X-16195) Phenol,4-chloro-7-iodo-