5-ISOTHIAZOLECARBOXYLIC ACID
- CAS No.
- 10271-85-9
- Chemical Name:
- 5-ISOTHIAZOLECARBOXYLIC ACID
- Synonyms
- 5-ISOTHIAZOLECARBOXYLIC ACID;ISOTHIAZOLE-5-CARBOXYLIC ACID;1,2-thiazole-5-carboxylic acid;8-Isoquinoline-methaneaminedihydrochloride
- CBNumber:
- CB2317896
- Molecular Formula:
- C4H3NO2S
- Molecular Weight:
- 129.14
- MDL Number:
- MFCD07369964
- MOL File:
- 10271-85-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Isothiazole-5-carboxylicacid | I917608 | 50mg | $55 |
| Isothiazole-5-carboxylic acid | 280318 | 100mg | $460 |
| Isothiazole-5-carboxylic acid | OR313078 | 1g | $513 |
| Isothiazole-5-carboxylic acid | OR313078 | 250mg | $210 |
| ISOTHIAZOLE-5-CARBOXYLIC ACID 95.00% | CHM0030214 | 1G | $1149.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H335-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| HS Code | 2934208090 |
5-ISOTHIAZOLECARBOXYLIC ACID price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | I917608 | Isothiazole-5-carboxylicacid | 10271-85-9 | 50mg | $55 | 2021-12-16 | Buy |
| Usbiological | 280318 | Isothiazole-5-carboxylic acid | 10271-85-9 | 100mg | $460 | 2021-12-16 | Buy |
| Apolloscientific | OR313078 | Isothiazole-5-carboxylic acid | 10271-85-9 | 1g | $513 | 2021-12-16 | Buy |
| Apolloscientific | OR313078 | Isothiazole-5-carboxylic acid | 10271-85-9 | 250mg | $210 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0030214 | ISOTHIAZOLE-5-CARBOXYLIC ACID 95.00% | 10271-85-9 | 1G | $1149.23 | 2021-12-16 | Buy |
5-ISOTHIAZOLECARBOXYLIC ACID Chemical Properties,Uses,Production
Uses
Isothiazole-5-carboxylic acid (8-Isoquinoline-methaneaminedihydrochloride) is an organic compound with antibacterial, anticancer and anti-inflammatory properties. Isothiazole-5-carboxylic acid can be used to develop novel compounds to combat various diseases. Isothiazole-5-carboxylic acid exhibits a wide range of potential pharmacological activities and helps improve existing inhibitory schemes.
Synthesis
15901-66-3
10271-85-9
Methyl isothiazole-5-carboxylate (0.50 g, 3.49 mmol) was dissolved in a THF/MeOH solvent mixture (20 mL/5 mL) at room temperature, followed by slow addition of 1N NaOH solution (5.24 mL, 5.24 mmol). The reaction mixture was stirred continuously for 16 h at room temperature and the completion of the reaction was confirmed by thin layer chromatography (TLC) monitoring. Upon completion of the reaction, the reaction mixture was acidified to pH 2 with 1N HCl solution, at which point a precipitate was observed to be generated. The precipitate was separated by filtration and dried to afford the target product isothiazole-5-carboxylic acid (Compound 2) as a beige solid in a yield of 0.35 g (76% yield). The structure of the product was confirmed by 1H-NMR (400 MHz, DMSO-d6) with chemical shifts of δ 8.69 (d, 1H) and 7.85 (d, 1H), respectively.
References
[1] Patent: US2007/105864, 2007, A1. Location in patent: Page/Page column 151-152
[2] Patent: US2007/117804, 2007, A1. Location in patent: Page/Page column 78
5-ISOTHIAZOLECARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
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Preparation Products
5-ISOTHIAZOLECARBOXYLIC ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29830 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49966 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +8618118463618 | sales1@artkmedchem.com | China | 39020 | 58 |
View Lastest Price from 5-ISOTHIAZOLECARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 5-ISOTHIAZOLECARBOXYLIC ACID
10271-85-9
|
US $1.00 / KG | 1KG | 99% | Customized | Career Henan Chemical Co |
-
- 5-ISOTHIAZOLECARBOXYLIC ACID
10271-85-9
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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