2-Methyl-3-nitrobenzyl alcohol
- CAS No.
- 23876-13-3
- Chemical Name:
- 2-Methyl-3-nitrobenzyl alcohol
- Synonyms
- (2-Methyl-3-nitrophenyl)Methanol;99.10%;Einecs 245-923-1;2-Methyl-3-Nitrobenzyl;2-METHYL-3-NITROBENZYL ALCOHOL;2-Methyl-3-nitrobenzyl alcohol,99%;Benzenemethanol, 2-methyl-3-nitro-;2-Methyl-3-nitrobenzyl alcohol 98%;3-(4-cyanophenyl)cyclopropane-1,1,2,2-tetracarbonitrile
- CBNumber:
- CB2327697
- Molecular Formula:
- C8H9NO3
- Molecular Weight:
- 167.16
- MDL Number:
- MFCD00007166
- MOL File:
- 23876-13-3.mol
- MSDS File:
- SDS
| Melting point | 69-73 °C (lit.) |
|---|---|
| Boiling point | 323.2±27.0 °C(Predicted) |
| Density | 1.272±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | solid |
| pka | 13.83±0.10(Predicted) |
| Appearance | Off-white to light yellow Solid |
| InChI | 1S/C8H9NO3/c1-6-7(5-10)3-2-4-8(6)9(11)12/h2-4,10H,5H2,1H3 |
| InChIKey | QJANIQCEDPJNLO-UHFFFAOYSA-N |
| SMILES | Cc1c(CO)cccc1[N+]([O-])=O |
| CAS DataBase Reference | 23876-13-3(CAS DataBase Reference) |
| FDA UNII | 1EX8SC1ETW |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
| HS Code | 2906290090 |
| Storage Class | 11 - Combustible Solids |
2-Methyl-3-nitrobenzyl alcohol price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 187291 | 2-Methyl-3-nitrobenzyl alcohol 99% | 23876-13-3 | 10g | $132 | 2023-01-07 | Buy |
| Apolloscientific | OR30524 | 2-Methyl-3-nitrobenzyl alcohol 98% | 23876-13-3 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR30524 | 2-Methyl-3-nitrobenzyl alcohol 98% | 23876-13-3 | 25g | $89 | 2026-06-04 | Buy |
| Apolloscientific | OR30524 | 2-Methyl-3-nitrobenzyl alcohol 98% | 23876-13-3 | 100g | $353 | 2026-06-04 | Buy |
| Apolloscientific | OR30524 | 2-Methyl-3-nitrobenzyl alcohol 98% | 23876-13-3 | 500g | $1491 | 2026-06-04 | Buy |
2-Methyl-3-nitrobenzyl alcohol Chemical Properties, Uses, Production
Chemical Properties
white to light yellow crystal powde
Uses
2-Methyl-3-nitrobenzyl alcohol was used to prepare 2-methyl-3-nitrobenzyl cyanide. It was also used in the synthesis of 20-membered macrocyclic thiodepsipeptide.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 28, p. 1533, 1985 DOI: 10.1021/jm00148a028
Synthesis
1975-50-4
23876-13-3
General procedure for the synthesis of 2-methyl-3-nitrobenzenemethanol from 2-methyl-3-nitrobenzoic acid: 500 mL of tetrahydrofuran (THF) and 76.5 g of sodium borohydride (NaBH4) were mixed and stirred for 30 min at ambient temperature. Subsequently, a THF solution of 2-methyl-3-nitrobenzoic acid (250 g dissolved in 750 mL of THF) was added and stirring was continued for 0.5 h at ambient temperature. Next, 90 mL of methanesulfonic acid was slowly added to the reaction mixture with continuous stirring until the reaction was complete. Upon completion of the reaction, the organic layer was isolated by acidifying the reaction mixture by adding hydrochloric acid followed by extraction with ethyl acetate. The ethyl acetate was removed by evaporation to give 2-methyl-3-nitrobenzyl alcohol as a yellow oil. It was further treated with cyclohexane and crystallized to finally obtain purified 2-methyl-3-nitrobenzyl alcohol (Yield: 210 g, Yield: 84%).
References
[1] Journal of Medicinal Chemistry, 1985, vol. 28, # 10, p. 1533 - 1536
[2] Patent: WO2006/123356, 2006, A1. Location in patent: Page/Page column 21
[3] European Journal of Medicinal Chemistry, 1995, vol. 30, # 12, p. 973 - 982
[4] Helvetica Chimica Acta, 1948, vol. 31, p. 65,74
[5] Patent: WO2013/162072, 2013, A1. Location in patent: Page/Page column 938
2-Methyl-3-nitrobenzyl alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Suzhou Lakestar Pharmatech Co., Ltd. | 0512-63970158-603 18018108880 | info@lakestarpharma.com | China | 400 | 59 |
| LUCKY PHARMA CO., LIMITED | 0571-86403260 86403970 | lucky@lkbiology.com | China | 241 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
View Latest Price from 2-Methyl-3-nitrobenzyl alcohol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | 2-Methyl-3-nitrobenzyl alcohol
23876-13-3
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- 2-Methyl-3-nitrobenzyl alcohol
23876-13-3
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
