eutypoid C
- CAS No.
- 1260669-24-6
- Chemical Name:
- eutypoid C
- Synonyms
- eutypoid C;Ferroptosis-IN-15;2(5H)-Furanone, 4-[(3,4-dihydroxyphenyl)methyl]-3-(4-hydroxyphenyl)-
- CBNumber:
- CB23352070
- Molecular Formula:
- C17H14O5
- Molecular Weight:
- 298.29
- MDL Number:
- MOL File:
- 1260669-24-6.mol
eutypoid C Chemical Properties, Uses, Production
Uses
Ferroptosis-IN-15 (compound 12) is a potent inhibitor of ferroptosis, with the EC50s of 0.76 and 0.67 μM in A375 cells and 786-O cells, respectively.Ferroptosis-IN-15 is a potential iron chelator and radical trapping antioxidant[1].
Definition
ChEBI: Eutypoid C is a butenolide that is furan-2(5H)-one substituted by a 3,4-dihydroxybenzyl group at position 4 and a 4-hydroxyphenyl group at position 3. It has been isolated from Penicillium species. It has a role as a Penicillium metabolite. It is a butenolide and a polyphenol.
References
[1] Zheng-Biao Zou, et al. Nigenolides A–H, 13 new microperfuranones with ferroptosis inhibitory activity from the deep-sea-derived Aspergillus niger. Bioorganic Chemistry Volume 153, December 2024, 107919
eutypoid C Preparation Products And Raw materials
Raw materials
Preparation Products
eutypoid C Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
