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| | eutypoid C Basic information |
| Product Name: | eutypoid C | | Synonyms: | eutypoid C;2(5H)-Furanone, 4-[(3,4-dihydroxyphenyl)methyl]-3-(4-hydroxyphenyl)-;Ferroptosis-IN-15 | | CAS: | 1260669-24-6 | | MF: | C17H14O5 | | MW: | 298.29 | | EINECS: | | | Product Categories: | | | Mol File: | 1260669-24-6.mol |  |
| | eutypoid C Chemical Properties |
| Boiling point | 645.1±55.0 °C(Predicted) | | density | 1.467±0.06 g/cm3(Predicted) | | pka | 9.72±0.30(Predicted) |
| | eutypoid C Usage And Synthesis |
| Uses | Ferroptosis-IN-15 (compound 12) is a potent inhibitor of ferroptosis, with the EC50s of 0.76 and 0.67 μM in A375 cells and 786-O cells, respectively.Ferroptosis-IN-15 is a potential iron chelator and radical trapping antioxidant[1]. | | Definition | ChEBI: Eutypoid C is a butenolide that is furan-2(5H)-one substituted by a 3,4-dihydroxybenzyl group at position 4 and a 4-hydroxyphenyl group at position 3. It has been isolated from Penicillium species. It has a role as a Penicillium metabolite. It is a butenolide and a polyphenol. | | References | [1] Zheng-Biao Zou, et al. Nigenolides A–H, 13 new microperfuranones with ferroptosis inhibitory activity from the deep-sea-derived Aspergillus niger. Bioorganic Chemistry Volume 153, December 2024, 107919 |
| | eutypoid C Preparation Products And Raw materials |
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