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KUROMANIN CHLORIDE

CAS No.
7084-24-4
Chemical Name:
KUROMANIN CHLORIDE
Synonyms
C3G;CYANIDIN-3-GLUCOSIDE;KuroManin;CHRYSANTHEMIN;CYANIDIN-3-O-GLUCOSIDE CHLORIDE;ASTERIN;CYANIDIN-3-GLUCOSIDE CHLORIDE;glucocyanidin;cyanidin-3-O-glu;cyanidin3-o-glucoside
CBNumber:
CB2338763
Molecular Formula:
C21H21ClO11
Molecular Weight:
484.84
MDL Number:
MFCD27665410
MOL File:
7084-24-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-02 08:02:09

KUROMANIN CHLORIDE Properties

storage temp. -20°C
solubility Acidic Methanol (Slightly), Water (Slightly)
form Solid
color Dark Red to Black
Stability Hygroscopic
InChIKey YTMNONATNXDQJF-UBNZBFALSA-N
SMILES O([C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C1=CC2=C(C=C(O)C=C2[O+]=C1C1C=CC(O)=C(O)C=1)O.[Cl-] |&1:1,2,3,5,7,r|
FDA UNII 8X15R84UEM
UNSPSC Code 41116107
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  24/25
WGK Germany  3
RTECS  DK1270000
HS Code  29389090
Storage Class 11 - Combustible Solids

KUROMANIN CHLORIDE price More Price(90)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL89616 Cyanidin 3-glucoside chloride phyproof? Reference Substance 7084-24-4 10MG $292 2026-04-30 Buy
Sigma-Aldrich 52976 Kuromanin chloride ≥95% (HPLC) 7084-24-4 1mg $273 2026-04-30 Buy
Sigma-Aldrich 1151935 Kuromanin chloride United States Pharmacopeia (USP) Reference Standard 7084-24-4 15mg $927 2026-04-30 Buy
Sigma-Aldrich 44689 Kuromanin chloride analytical standard 7084-24-4 5mg $430 2022-05-15 Buy
Cayman Chemical 16406 Cyanidin 3-O-glucoside (chloride) ≥95% 7084-24-4 500μg $90 2026-04-30 Buy
Product number Packaging Price Buy
PHL89616 10MG $292 Buy
52976 1mg $273 Buy
1151935 15mg $927 Buy
44689 5mg $430 Buy
16406 500μg $90 Buy

KUROMANIN CHLORIDE Chemical Properties, Uses, Production

Plant Source

Anthocyanin also called anthocyanidin, is the main color substances in plant flowers and fruit. It is honored as the 7th essential nutrients of the human body after water, protein, fat, carbohydrates, Vitamins and minerals.  Thus, it becomes the most perspective natural pigment. Mulberry anthocyanins has been approved by the Ministry of public health as a kind of food additive and widely used in food and health care products. Cyanidin-3-O-glucoside is one of the main ingredients of mulberry anthocyanins. Black soy bean is a traditional kind of crops in our country.  It has a long food and medical history. Black soybean has been used for enriching the blood, activating the blood and Ufa beauty since the ancient times. Black bean peel, also called black clothes is the dry and mature skin of black soybean which is a kind of leguminous plants.  It is rich in anthocyanins which mainly consist of delphinium and cyaniding. It has lots of healthgiving benefits such as antioxidant activity, Inhibiting mutagenesis, anti-inflammatory, prevention of cancer, anti-aging, etc. It has been a raw material of natural food additives and healthcare food.
Until now, only Korean scholar Lee reported 5 kinds of anthocyanins separated from black bean peel as the following: Cyanidin-3-O-glucoside,delphinidin-3-O-glucoside, petunidin-3-O-glucoside, malvidin-3-O-glucoside and Cyanidin. In addition, some research papers reported that Cyanidin-3-O-glucoside is an important ingredient of black bean peel.
Anthocyanin, as a kind of flavonoid plant chemicals, occurs ubiquitously in pants. Anthocyanins extracted from food or plants often contain different anthocyanins such as cyaniding, pelargonidin, petunidin, malvidin, etc. Glucoside can also be divided into single, double, three glucoside structures and anthocyanins with different structure have different biological activities.
Anthocyanin has many therapeutic effects such as antioxidant, Anti-atherosclerosis, adjusting blood fat, etc. cyanidin-3-O-β-glucoside is one of the main ingredients of Anthocyanin.
A new study claims that purple corn anthocyanin can inhibit the body weight growth of high-fat induced mice. But its effective components and the mechanism is not clear. It is speculated that the 7% content of Chrysanthemin in purple corn anthocyanins played a leading role.

Analysis method

The main Analysis method for Chrysanthemin is high performance liquid chromatography (HPLC). Chromatographic analysis condition is commonly as the following: chromatographic column: Phe nomenex Luna Su C18 (250mm×4.60mm,5μm); mobile phase: phase A is 0.5 % Phosphoric acid solution,phase B is water-acetonitrile (50: 50,V/ V). gradient elution:0min(18%B),23min(50%B),28min(18%B),33min(18%B),40min(stop);flow velocity:0.8mL/min;Detection wavelength:520nm;column temperature:30℃. Figure 1 shows the high performance liquid chromatogram (HPLC) figure of cyanidin-3-O-glucoside(Chrysanthemin) in mulberry extracting solution.

Pharmacological effects

Modern pharmacology study indicated that C3G has many significant medical and health care effects such as antioxidant, anti-tumor, protecting the nervous system, recovering Transient visual impairment, etc. In addition, studies indicated that Chrysanthemin can be used as protective agent for protecting cotton leaves against cotton bollworm.
C3G in Black bean peel can reduce the production of reactive oxygen species in 3T3-L1fat cells, thus, Dose dependently improved the resistance of H2O2 or TNF-α induced insulin. At the same time, it can reduce the expression of retinol-binding protein in type II diabetic rats, thus, improve hyperglycemia and insulin sensitivity and the symptoms of diabetes.

Antioxidant activity

Kuromanin chloride is phytochemical rich in plants and fruits and has remarkable anti-oxidant activity, resulting in it an ideal nutrient for nutritional intervention. The antioxidant activity of kuromanin chloride was evaluated by the DPPH and ABTS assay on GES-1 cells. The results showed that kuromanin chloride possessed obvious antioxidant effects, and also could decrease the ROS level in cells and had negligible effects on the viability of cells. Bulent groups analyzed the antioxidant activity of kuromanin chloride by ferric reducing antioxidant power, indicating that kuromanin chloride was the predominant antioxidant compared with anthocyanin in all blackberry fruits. In addition, by alleviating oxidative stress, strengthening the anti-oxidative system, and chelating with Cd ion, kuromanin chloride has the ability to against Cd-induced damage in various organs such as Cd-induced dysfunction of sex hormones, Cd-induced male reproductive toxicity and spermatogenesis disturbances, and Cd-induced kidney damage.

Antitumor effects

Kuromanin chloride have been proved that has antitumor effects. Treating PC-3 human prostate cancer cells with kuromanin chloride could induce apoptosis, activate caspase signaling pathway and loss of mitochondrial membrane potential, suggesting the prominent anticarcinogenic activity of kuromanin chloride. Kuromanin chloride also has been shown to inhibit the growth and metastatic potential of melanoma via estrogen receptor beta. These studies suggested that kuromanin chloride is a potential novel therapeutic and preventive approach for tumor.

Cytoprotective effects

Kuromanin chloride also exhibited cytoprotective effects. For example, experiments showed that kuromanin chloride could against the glucotoxicity‑induced apoptosis of pancreatic β‑cells, indicating the antidiabetic effects of kuromanin chloride. Moreover, kuromanin chloride also has other potential therapeutic effects, such as rheumatoid arthritis, the cognitive function in older adults with subjective memory impairment, neuroprotective effects, UVA-induced human dermal fibroblast injury by upregulating autophagy, and so on. All these suggested that kuromanin chloride is the potential therapeutic medicine for multiple diseases.

Storage

It is reported that long time high temperature and light has an obvious destructive effect on Mulberry Anthocyanins.  At room temperature, the degradation rate of mulberry Chrysanthemin increased significantly with the extension of storage time.  In long-term exposure to air, the light might induce the   degradation of Chrysanthemin. The specific reasons need to be further studied.  Therefore, anthocyanin extraction should be carried out in time after picking mulberry fruit. In addition fresh mulberry fruit should be stored in a cool, well-ventilated warehouse.

Chemical Properties

Purple powder

Uses

Cyanidol 3-Glucoside is a anthocyanin that is naturally occurring in various fruits, vegetable and plants. Cyanidol 3-Glucoside is known to exhibit high antioxidant capacity and neuroprotective effects by triggering mobilization of cellular free sialic acid and utilizing it as an additional biological antioxidant in brain neural cells.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Anthocyanin. Antioxidant. Studied for its neuroprotective property.

KUROMANIN CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 362)
Supplier Tel Email Country ProdList Advantage
Shaanxi Delavite Biotechnology Co., Ltd. 15780788769 18292741956 409357995@qq.com China 489 58
Nanjing Yuanzhi Biotechnology Co. Ltd. 15805159960; 1211550495@qq.com China 1797 58
Chengdu Nakeli Biotechnology Co., Ltd. 028-61983833 19138982515 3265827856@qq.com China 1584 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79
Aemon Chemical 0086-755-86198205 acinfo@aemonchem.com China 1928 57
Shenzhen Sungening Bio-Tech Co., Ltd +86-0755-89668383 sales@sungening.com China 1319 65

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View Latest Price from KUROMANIN CHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
KUROMANIN CHLORIDE pictures 2026-09-18 KUROMANIN CHLORIDE
7084-24-4
$666.00-999.00 1g 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
KUROMANIN CHLORIDE pictures 2026-08-03 KUROMANIN CHLORIDE
7084-24-4
1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd
Cyanidin-3-O-glucoside chloride pictures 2023-02-24 Cyanidin-3-O-glucoside chloride
7084-24-4
5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.

KUROMANIN CHLORIDE Spectrum

KUROMANIN CHLORIDE KUROMANINE CHLORIDE cyanidine3-glucoside cyanidol3-glucoside glucocyanidin CYANIDIN-3-O-BETA-GLUCOPYRANOSIDE CYANIDIN3-O-BETA-D-GLUCOSIDE CYANIDIN3-O-BETA-D-GLUCOPYRANOSIDE ASTERIN hplc KUROMANIN CHLORIDE WITH HPLC Asterin, Chrysanthemin, Cyanidin 3-O-glucoside chloride Cyanidin 3-O-β-D-glucopyranoside Cyanidin 3-O-β-D-glucoside CYANIDIN-3-O-GLUCOSIDE CHLORIDE(KUROMANIN CHLORIDE)(SH) CYANIDIN-3-O-GLUCOSIDE CHLORIDE(KUROMANIN CHLORIDE)(RG) Cyanidin-3-O-glucoside Chloride (15 mg) chrysontemin cyanidin3-beta-glucoside cyanidin3-monoglucoside 1-benzopyrylium,5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-3-(beta-d-glucopyranosyl 2-(3,4-Dihydroxyphenyl)-3-(.beta.-D-glucopyranosyloxy)-5,7-dihydroxy-1-benzopyryliumchloride CYANIDIN-3-O-GLUCOSIDE CHLORIDE, KuroManin chloride Cyanidin-3-O-glucoside chloride, froM GlycineMax (L.) Merr. KuroManine 1-BenzopyryliuM-2-(3,4-dihydroxyphenyl)-3-(b-D-glucopyranosyloxy)-5,7-dihydroxy-chloride 1-BenzopyryliuM,2-(3,4-dihydroxyphenyl)-3-(b-D-glucopyranosyloxy)-5,7-dihydroxy-, chloride (1:1) Cyanidin-3-O- glucoside chloride C-3-G Cyanidin-3-O-glucoside chloride, 98%, from Glycine max (L.) merr. Chrysontemin chloride Glucocyanidin chloride cyanidin3-O-β-D-glucoside cyanidin 3-O-β-glucopyranoside chloride Cyanidin-3-O-glucoside Chloride (1151935) 6-anhydro-b-D-Glucose 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)chromenylium chloride Cyanidin-3-O-Glucoside Chloride (Kuromanin Chloride) (P) 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-3,4,5,6-tetrahydro-2H-pyran-2-yl]oxy}chromen-1-ium 2- (3,4-dihydroxyphenyl) -5,7-dihydroxy-3- (((2S, 3R, 4S, 5S, 6R) -3,4,5-trihydroxy-6- (hydroxymethyl) tetrahydro-2H-pyran-2-yl) oxy) benzopyran chloride Cyanidin 3-glucoside chloride-RM Cyanidin-3-O-Glucoside ChlorideP) Cyanidin 3-glucoside-RM Famitinib Impurity 12 Jaceosidin Impurity 1 Kuromanin chloride, 10 mM in DMSO Cyanidin 3-O-glucoside chloride 1-?Benzopyrylium, 2-?(3,?4-?dihydroxyphenyl)?-?3-?(β-?D-?glucopyranosyloxy)?-?5,?7-?dihydroxy-?, chloride (1:1) Kuromanin chloride (Standard) ASTERIN C3G CHRYSANTHEMIN CYANIDIN-3-O-GLUCOSIDE CHLORIDE cyanidin-3-O-glu cyanidin3-o-glucoside CYANIDIN-3-GLUCOSIDE CYANIDIN-3-GLUCOSIDE CHLORIDE KuroManin Purple sweet potato extract (main component is anthocyanin, cyanidin-3-glucoside as an example) 7084-24-4