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2-Chloro-1,3-dinitrobenzene

CAS No.
606-21-3
Chemical Name:
2-Chloro-1,3-dinitrobenzene
Synonyms
2,6-DINITROCHLOROBENZENE;Bendamustine Impurity 53;Vortioxetine Impurity 65;2,6-Dinitrophenyl chloride;2-Chloro-1,3-dintrobenzene;2-chloro-1,3-dinitro-benzen;1,3-Dinitro-2-chlorobenzene;1-CHLORO-2,6-DINITROBENZENE;2-CHLORO-1,3-DINITROBENZENE;2,6-Dinitro-1-Chlorobenzene
CBNumber:
CB2340629
Molecular Formula:
C6H3ClN2O4
Molecular Weight:
202.55
MDL Number:
MFCD00014689
MOL File:
606-21-3.mol
MSDS File:
SDS
Last updated:2026-05-28 00:23:02

2-Chloro-1,3-dinitrobenzene Properties

Melting point 86-88°C
Boiling point 315°C
Density 1,687 g/cm3
refractive index 1.5870 (estimate)
Flash point 315°C
storage temp. 2-8°C
form solid
color Pale-yellow to Yellow-brown
Water Solubility Soluble in alcohol. Moderately soluble in benzene, ether. Practically insoluble in water.
Merck 14,2137
BRN 522187
Henry's Law Constant 1.6×102 mol/(m3Pa) at 25℃, Zhang et al. (2010)
InChI InChI=1S/C6H3ClN2O4/c7-6-4(8(10)11)2-1-3-5(6)9(12)13/h1-3H
InChIKey BPPMIQPXQVIZNJ-UHFFFAOYSA-N
SMILES C1([N+]([O-])=O)=CC=CC([N+]([O-])=O)=C1Cl
CAS DataBase Reference 606-21-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII LG72RND0AB
NIST Chemistry Reference 1-Chloro-2,6-dinitrobenzene(606-21-3)
EPA Substance Registry System 2,6-Dinitrochlorobenzene (606-21-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H300-H310-H330-H373-H400-H410
Precautionary statements  P301+P310a-P304+P340-P320-P330-P405-P501a
Risk Statements  23/24/25-33-50/53
Safety Statements  28-36/37-45-60-61
RIDADR  3441
RTECS  CZ0525500
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  II
HS Code  29049090
Hazardous Substances Data 606-21-3(Hazardous Substances Data)
NFPA 704
1
4 0

2-Chloro-1,3-dinitrobenzene price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 267307 1-Chloro-2,6-dinitrobenzene Asreported 606-21-3 1g $418 2026-06-03 Buy
Usbiological 267307 1-Chloro-2,6-dinitrobenzene Asreported 606-21-3 2g $602 2026-06-03 Buy
Usbiological 267307 1-Chloro-2,6-dinitrobenzene Asreported 606-21-3 5g $955 2026-06-03 Buy
Usbiological 267307 1-Chloro-2,6-dinitrobenzene Asreported 606-21-3 10g $1310 2026-06-03 Buy
Usbiological 267307 1-Chloro-2,6-dinitrobenzene Asreported 606-21-3 25g $2088 2026-06-03 Buy
Product number Packaging Price Buy
267307 1g $418 Buy
267307 2g $602 Buy
267307 5g $955 Buy
267307 10g $1310 Buy
267307 25g $2088 Buy

2-Chloro-1,3-dinitrobenzene Chemical Properties,Uses,Production

Chemical Properties

Yellow crystals. Soluble in ethanol, ether, and toluene

Uses

The commercial mixture of chlorodinitrobenzenes is used to synthesize other compounds.

Uses

2-Chloro-1,3-dinitrobenzene can be used as intermediates of dyes and pigments. Also used as solvents in HPLC, NMR.

Uses

2,6-Dinitrochlorobenzene (2-Chloro-1,3-dinitrobenzene) is a thiol-modifying agent.

Hazard

Toxic if swallowed. Toxic in contact with skin. Fatal if inhaled. May cause damage to organs through prolonged or repeated exposure. Very toxic to aquatic life with long lasting effects.

Synthesis

The synthesis of 2-Chloro-1,3-dinitrobenzene is as follows:
Add 800ml of sulfolane as solvent to a 2L flask, then add 246.5g of 3,5-dinitro-4-chlorobenzoic acid and 168g of sodium bicarbonate,Heat to 195°C to react for 2h. After the reaction is complete, cool to 130°C and distill under reduced pressure.The product 2-Chloro-1,3-dinitrobenzene, 178.4g, was obtained by rectification with a yield of 88.1%.
synthesis of 2-Chloro-1,3-dinitrobenzene.png

Global( 147)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanbu County Chengxin Technology Co., Ltd. 0838-5675166 15883665058 nbcxkj@126.com China 956 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57

View Lastest Price from 2-Chloro-1,3-dinitrobenzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-1,3-dinitrobenzene pictures 2026-03-20 2-Chloro-1,3-dinitrobenzene
606-21-3
1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Chloro-1,3-dinitrobenzene pictures 2020-01-08 2-Chloro-1,3-dinitrobenzene
606-21-3
$3.00 1KG 98% 200KG Career Henan Chemical Co
1-CHLORO-2,6-DINITROBENZENE 1,3-Dinitro-2-chlorobenzene 2-chloro-1,3-dinitro-benzen 2-Chloro-1,3-dintrobenzene 2,6-Dinitrophenyl chloride 2,6-Dinitro-1-Chlorobenzene Benzene, 2-chloro-1,3-dinitro- 1-Chloro-2,6-dinitrobenzene~2,6-Dinitrochlorobenzene 2-CHLORO-1,3-DINITROBENZENE 2-Chloro-1,3-dinitrobenzene, 98+% Bendamustine Impurity 53 606-21-3 2-Chloro-1,3-dinitrobenzene Vortioxetine Impurity 65 2-Chloro-1,3-dinitrobenzene in isopropanol 2,6-DINITROCHLOROBENZENE 606-21-3 NO22ClC6H3 Intermediates of Dyes and Pigments Alcohols and Derivatives