ChemicalBook >> CAS DataBase List >>2-Chloro-N,N-dimethylacetamide

2-Chloro-N,N-dimethylacetamide

2-Chloro-N,N-dimethylacetamide structure

CAS No.: 2675-89-0

Chemical Name:: 2-Chloro-N,N-dimethylacetamide

Synonyms: N,N-DIMETHYLCHLOROACETAMIDE;EOS-61825;AKOS BBS-00000943;2-Chloro-N,N-dimethy;CHLOROACETYLDIMETHYLAMINE;N,N-DIMETHYLCHOROACETAMIDE;N-DiMethyl-2-chloroacetaMide;2-Chloro-N,N-dimethylacetamid;N,N-DIMETHYL-2-CHLOROACETAMIDE;2-CHLORO-N,N-DIMETHYLACETAMIDE

CBNumber:: CB2343589

Molecular Formula:: C4H8ClNO

Molecular Weight:: 121.57

MDL Number:: MFCD00039360

MOL File:: 2675-89-0.mol

MSDS File:: SDS

Last updated:2026-05-28 00:19:34

Product description	Number	Pack Size	Price
2-Chloro-N,N-dimethylacetamide ≥97.0% (GC)	24350	25mL	$379
2-Chloro-N,N-dimethylacetamide	C3011	5G	$30
2-Chloro-N,N-dimethylacetamide	C3011	25G	$102
2-Chloro-N,N-dimethylacetamide ≥97%(GC)	33525	100G	$350.93
2-Chloro-N,N-dimethylacetamide ≥97%(GC)	33525	250G	$827.84
More product size

Request For Quotation

2-Chloro-N,N-dimethylacetamide Properties

Melting point	15-16 °C
Boiling point	98-100°C/11mm
Density	1.182 g/mL at 20 °C (lit.)
refractive index	n20/D 1.479
Flash point	98-100°C/11mm
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly), Hexane (Slightly), Methanol (Slightly)
pka	-0.95±0.70(Predicted)
form	Liquid
color	Clear colorless to pale yellow
BRN	969568
InChI	1S/C4H8ClNO/c1-6(2)4(7)3-5/h3H2,1-2H3
InChIKey	XBPPLECAZBTMMK-UHFFFAOYSA-N
SMILES	CN(C)C(=O)CCl
CAS DataBase Reference	2675-89-0(CAS DataBase Reference)
FDA UNII	7W3TRD462F
UNSPSC Code	12352111
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H314

Precautionary statements

P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338

PPE

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

22-34

Safety Statements

26-36/37/39-45

RIDADR

UN 3265 8/PG 3

WGK Germany

HazardClass

HS Code

29241990

Storage Class

8A - Combustible corrosive hazardous materials

Hazard Classifications

Acute Tox. 4 Oral
Skin Corr. 1B

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	1
3		0

2-Chloro-N,N-dimethylacetamide price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	24350	2-Chloro-N,N-dimethylacetamide ≥97.0% (GC)	2675-89-0	25mL	$379	2026-04-30	Buy
TCI Chemical	C3011	2-Chloro-N,N-dimethylacetamide	2675-89-0	5G	$30	2026-04-30	Buy
TCI Chemical	C3011	2-Chloro-N,N-dimethylacetamide	2675-89-0	25G	$102	2026-04-30	Buy
Chem-Impex	33525	2-Chloro-N,N-dimethylacetamide ≥97%(GC)	2675-89-0	100G	$350.93	2026-05-19	Buy
Chem-Impex	33525	2-Chloro-N,N-dimethylacetamide ≥97%(GC)	2675-89-0	250G	$827.84	2026-05-19	Buy

Product number	Packaging	Price	Buy
24350	25mL	$379	Buy
C3011	5G	$30	Buy
C3011	25G	$102	Buy
33525	100G	$350.93	Buy
33525	250G	$827.84	Buy

2-Chloro-N,N-dimethylacetamide Chemical Properties,Uses,Production

Uses

2-Chloro-N,N-dimethylacetamide is N,M-dialkyl amide used as an organic catalyst in the preparation of phosphorylated thiosemicarbazide.

Uses

2-Chloro-N,N-dimethylacetamide (N,N-dimethylchloroacetamide) was used in the synthesis of (S)-carbinoxamine.

Synthesis

In a 500 mL four-necked flask, sodium hydrogen carbonate 126.0 g (1.50 mol) and 146.8 g of toluene were added, and the mixture was stirred while cooling. The internal temperature was maintained below 5 ° C, 112.9 g (1.00 mol) of chloroacetyl chloride was added dropwise over 4 hours, and 49.6 g (1.10 mol) of dimethylamine gas was blown over 4 hours. After stirring at -2 to 1 ° C. for 1 hour, the reaction solution was filtrated under reduced pressure to remove inorganic salt crystals by filtration. The crystals were washed with 100 g of toluene, and the filtrate and washings were combined. After separating and removing the aqueous layer in the filtrate washings, the toluene layer was concentrated under reduced pressure to obtain 113.2 g (0.93 mol) of oily 2-chloro-N, N-dimethylacetamide. The yield was 93.1%.
2-Chloro-N,N-dimethylacetamide

2-Chloro-N,N-dimethylacetamide synthesis

Synthesis of 2-Chloro-N,N-dimethylacetamide from Dimethylamine hydrochloride and Chloroacetyl chloride

2-Chloro-N,N-dimethylacetamide Preparation Products And Raw materials

Raw materials

Dimethylamine hydrochloride Chloroacetyl chloride Sodium bicarbonate Dichloromethane Sodium hydroxide

Dimethylamine

1of2

Preparation Products

N-ME-GLY-NME2 2-Chloro-N-phenylacetamide 2-diethoxyphosphoryl-N,N-dimethylacetamide

2-Chloro-N,N-dimethylacetamide Suppliers

Global( 289)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaoxing Fangxiao Chemical Co., LTD	+86-13456999252 +86-13868192239	kenny@fangxiaochem.com	China	50	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Hebei shuoxi biotechnology co. LTD	+8613081092107		CHINA	964	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58

Supplier	Advantage
Shaoxing Fangxiao Chemical Co., LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
Shandong chuangyingchemical Co., Ltd.	58
Hebei shuoxi biotechnology co. LTD	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from 2-Chloro-N,N-dimethylacetamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	2-Chloro-N,N-dimethylacetamide 2675-89-0		1KG	99%	20 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-04-04	2-Chloro-N,N-dimethylacetamide 2675-89-0		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-07-13	N,N-Dimethyl-2-chloroacetamide 2675-89-0	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

2-Chloro-N,N-dimethylacetamide
2675-89-0
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-Chloro-N,N-dimethylacetamide
2675-89-0
98%
Henan Aochuang Chemical Co.,Ltd.

N,N-Dimethyl-2-chloroacetamide
2675-89-0
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

2-Chloro-N,N-dimethylacetamide Spectrum

2-Chloro-N,N-dimethylacetamide(2675-89-0)¹HNMR

2675-89-0(2-Chloro-N,N-dimethylacetamide)Related Search:

Chloroacetamide Chlorodimethylphenylsilane DIMETHYLTHEXYLSILYL CHLORIDE Epichlorohydrin 2,6-Dimethylphenol

2,6-Lutidine Dichloroacetamide 2,2,2-Trichloroacetamide tert-Butyldimethylsilyl chloride N,N-Dimethylacetamide

Difluorochloromethane Chloroacetic acid 2-Chloro-N,N-bis(2-methylpropyl)acetamide FLUOROIMIDE 2-Chloro-N,N-diethylacetamide

Alachlor ALLIDOCHLOR Acetamide

1of4

N,N-DIMETHYL-2-CHLOROACETAMIDE N,N-DIMETHYLCHOROACETAMIDE CHLOROACETYLDIMETHYLAMINE AKOS BBS-00000943 2-CHLORO-N,N-DIMETHYLACETAMIDE 2-chloro-N,N-dimethyl-ethanamide 2-Chloro-N,N-dimethylacetacetamide 2-Chloro-N,N-dimethy 2-Chloro-N,N-Dimethyl Butylamine 2-CHLORO-N,N-DIMETHYL ACETAMINE Acetamide, 2-chloro-N,N-dimethyl- 2-CHLORO-N N-DIMETHYLACETAMIDE 98 % N-DiMethyl-2-chloroacetaMide 2-chloro -N,N- two MethylacetaMide 2-Chloro-N,N-dimethylacetamide >=97.0% (GC) EOS-61825 2675-89-0 C4H8ClNO 2-Chloro-N,N-dimethylacetamide 2-Chloro-N,N-dimethylacetamide, 97%, 2-Chloro-N,N-dimethylacetamide 2-Chloro-N,N-dimethylacetamid N,N-DIMETHYLCHLOROACETAMIDE 2675-89-0 ClCH2CONCH32 Carbonyl Compounds Building Blocks Amides Organic Building Blocks 2675-89-0