2-Chloro-N,N-dimethylacetamide
- CAS No.
- 2675-89-0
- Chemical Name:
- 2-Chloro-N,N-dimethylacetamide
- Synonyms
- N,N-DIMETHYLCHLOROACETAMIDE;EOS-61825;AKOS BBS-00000943;2-Chloro-N,N-dimethy;CHLOROACETYLDIMETHYLAMINE;N,N-DIMETHYLCHOROACETAMIDE;N-DiMethyl-2-chloroacetaMide;2-Chloro-N,N-dimethylacetamid;N,N-DIMETHYL-2-CHLOROACETAMIDE;2-CHLORO-N,N-DIMETHYLACETAMIDE
- CBNumber:
- CB2343589
- Molecular Formula:
- C4H8ClNO
- Molecular Weight:
- 121.57
- MDL Number:
- MFCD00039360
- MOL File:
- 2675-89-0.mol
- MSDS File:
- SDS
| Melting point | 15-16 °C |
|---|---|
| Boiling point | 98-100°C/11mm |
| Density | 1.182 g/mL at 20 °C (lit.) |
| refractive index |
n |
| Flash point | 98-100°C/11mm |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Slightly), Hexane (Slightly), Methanol (Slightly) |
| pka | -0.95±0.70(Predicted) |
| form | Liquid |
| color | Clear colorless to pale yellow |
| BRN | 969568 |
| InChI | 1S/C4H8ClNO/c1-6(2)4(7)3-5/h3H2,1-2H3 |
| InChIKey | XBPPLECAZBTMMK-UHFFFAOYSA-N |
| SMILES | CN(C)C(=O)CCl |
| CAS DataBase Reference | 2675-89-0(CAS DataBase Reference) |
| FDA UNII | 7W3TRD462F |
| UNSPSC Code | 12352111 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314 | |||||||||
| Precautionary statements | P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 22-34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3265 8/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 8 | |||||||||
| HS Code | 29241990 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Skin Corr. 1B |
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| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
2-Chloro-N,N-dimethylacetamide price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 24350 | 2-Chloro-N,N-dimethylacetamide ≥97.0% (GC) | 2675-89-0 | 25mL | $379 | 2026-04-30 | Buy |
| TCI Chemical | C3011 | 2-Chloro-N,N-dimethylacetamide | 2675-89-0 | 5G | $30 | 2026-04-30 | Buy |
| TCI Chemical | C3011 | 2-Chloro-N,N-dimethylacetamide | 2675-89-0 | 25G | $102 | 2026-04-30 | Buy |
| TRC | TRC-C365705-50G | 2-Chloro-N,N-dimethylacetamide | 2675-89-0 | 50g | $246 | 2026-06-03 | Buy |
| TRC | TRC-C365705-25G | 2-Chloro-N,N-dimethylacetamide | 2675-89-0 | 25g | $139 | 2026-06-03 | Buy |
2-Chloro-N,N-dimethylacetamide Chemical Properties, Uses, Production
Uses
2-Chloro-N,N-dimethylacetamide is N,M-dialkyl amide used as an organic catalyst in the preparation of phosphorylated thiosemicarbazide.
Uses
2-Chloro-N,N-dimethylacetamide (N,N-dimethylchloroacetamide) was used in the synthesis of (S)-carbinoxamine.
Synthesis
In a 500 mL four-necked flask, sodium hydrogen carbonate 126.0 g (1.50 mol) and 146.8 g of toluene were added, and the mixture was stirred while cooling. The internal temperature was maintained below 5 ° C, 112.9 g (1.00 mol) of chloroacetyl chloride was added dropwise over 4 hours, and 49.6 g (1.10 mol) of dimethylamine gas was blown over 4 hours. After stirring at -2 to 1 ° C. for 1 hour, the reaction solution was filtrated under reduced pressure to remove inorganic salt crystals by filtration. The crystals were washed with 100 g of toluene, and the filtrate and washings were combined. After separating and removing the aqueous layer in the filtrate washings, the toluene layer was concentrated under reduced pressure to obtain 113.2 g (0.93 mol) of oily 2-chloro-N, N-dimethylacetamide. The yield was 93.1%.
2-Chloro-N,N-dimethylacetamide Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Shunyi Pharmaceutical Chemical Co., Ltd. | 15360832999;13560093877 | jasontim@shuntongchem.cn | China | 41 | 58 |
| Suzhou Muyuanda Biotechnology Co., Ltd | 021-37318802 18616909727 | liangpanpan@sh-jiaoze.com | China | 124 | 58 |
| Creasyn Finechem(Tianjin) Co., Ltd. | 022-83946278 13820372920 | sales@creasyn.com | China | 968 | 68 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Latest Price from 2-Chloro-N,N-dimethylacetamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | 2-Chloro-N,N-dimethylacetamide
2675-89-0
|
1kg /Drum | ≥98% | 50 T/Month | Hebei Qujie Technology Co., Ltd. | ||
 |
2026-03-20 | 2-Chloro-N,N-dimethylacetamide
2675-89-0
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2025-04-04 | 2-Chloro-N,N-dimethylacetamide
2675-89-0
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 2-Chloro-N,N-dimethylacetamide
2675-89-0
- $0.00
- ≥98%
- Hebei Qujie Technology Co., Ltd.
-
- 2-Chloro-N,N-dimethylacetamide
2675-89-0
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-Chloro-N,N-dimethylacetamide
2675-89-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
