2-Fluoro-6-methoxyphenylboronic acid
- CAS No.
- 78495-63-3
- Chemical Name:
- 2-Fluoro-6-methoxyphenylboronic acid
- Synonyms
- AKOS BRN-0424;2-Fluoro-6-methoxyph;uoro-6-methoxyphenyL;2-Borono-3-fluoroanisole;Fluoro-6-Methoxyphenylboronic;3-Fluoroanisole-2-boronic acid;2-Fluoro-6-Methoxyphenylboroni;2-Fluoro-6-methoxyphenylboronicaci;6-Fluoro-2-methoxyphenylboronic acid;2-FLUORO-6-METHOXYPHENYLBORONIC ACID
- CBNumber:
- CB2358204
- Molecular Formula:
- C7H8BFO3
- Molecular Weight:
- 169.95
- MDL Number:
- MFCD02179483
- MOL File:
- 78495-63-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 120-125 °C (lit.) |
|---|---|
| Boiling point | 303.1±52.0 °C(Predicted) |
| Density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 8.35±0.58(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C7H8BFO3/c1-12-6-4-2-3-5(9)7(6)8(10)11/h2-4,10-11H,1H3 |
| InChIKey | XOVMDVZAWWQSDC-UHFFFAOYSA-N |
| SMILES | B(C1=C(OC)C=CC=C1F)(O)O |
| CAS DataBase Reference | 78495-63-3(CAS DataBase Reference) |
| FDA UNII | AGF9KE4GA6 |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36/37/39-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2931900090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
2-Fluoro-6-methoxyphenylboronic acid price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 512761 | 2-Fluoro-6-methoxyphenylboronic acid ≥95% | 78495-63-3 | 5g | $161 | 2023-06-20 | Buy |
| Sigma-Aldrich | 512761 | 2-Fluoro-6-methoxyphenylboronic acid ≥95% | 78495-63-3 | 1g | $34.2 | 2022-05-15 | Buy |
| TCI Chemical | F0941 | 2-Fluoro-6-methoxyphenylboronic Acid (contains varying amounts of Anhydride) | 78495-63-3 | 1g | $21 | 2026-04-30 | Buy |
| TCI Chemical | F0941 | 2-Fluoro-6-methoxyphenylboronic Acid (contains varying amounts of Anhydride) | 78495-63-3 | 5g | $67 | 2026-04-30 | Buy |
| ChemScene | CS-0007649 | 2-Fluoro-6-methoxybenzeneboronic acid ≥95% | 78495-63-3 | 25g | $18 | 2026-06-04 | Buy |
2-Fluoro-6-methoxyphenylboronic acid Chemical Properties, Uses, Production
Preparation
Under effective stirring, a suspension of reduced iron powder (50 mmol) in 80 mL of ethanol was added to concentrated hydrochloric acid (5 mmol), heated at 65 °C for 0.5 h, and then cooled to 55–60 °C over 10 min. Then, 8 mL of 25% ammonium chloride aqueous solution was added. Substituted 4-bromo-nitronaphthalene (10 mmol) was added in portions (exothermic) while maintaining the internal temperature at 65–80 °C. The mixture was stirred at 55–65 °C for another 1–3 h and cooled to 40 °C. Diatomaceous earth was added, and the mixture was filtered through a diatomaceous earth mat. The filter cake was washed with dichloromethane (20 mL), and the liquid phase was extracted with dichloromethane. The organic phase was dried over sodium sulfate and concentrated under reduced pressure to obtain the desired 4-bromo-1-naphthylamine.
Uses
Reactant for:• ;Preparation of functionally selective allosteric modulators of GABAA receptors1• ;Suzuki cross-coupling reaction2,3• ;Preparation of inhibitors of the checkpoint kinase Wee14
Uses
suzuki reaction
Uses
2-Fluoro-6-methoxyphenylboronic Acid is a boronic acid derivative known for its pharmacological activity and utility as intermediates in the synthesis of novel non-boron containing compounds, and potential bacterial mutagens.
2-Fluoro-6-methoxyphenylboronic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tianjin Scaxchem Limited Compnay | 18630949181 | sales@cosychem.com | China | 657 | 55 |
| Zhuhai Aobokai Biomedical Technology Co., Ltd. | 400-0628126 | sales-team@aobchem.com.cn | China | 49995 | 58 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Latest Price from 2-Fluoro-6-methoxyphenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 2-Fluoro-6-methoxyphenylboronic acid
78495-63-3
|
$1.20-34.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-06-20 | 2-Fluoro-6-methoxyphenylboronic acid
78495-63-3
|
1kg | 99.50% | 20tons | Hebei Yanxi Chemical Co., Ltd. | ||
 |
2021-07-13 | 2-Fluoro-6-methoxyphenylboronic acid
78495-63-3
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 2-Fluoro-6-methoxyphenylboronic acid
78495-63-3
- $1.20-34.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 2-Fluoro-6-methoxyphenylboronic acid
78495-63-3
- $0.00
- 99.50%
- Hebei Yanxi Chemical Co., Ltd.
-
- 2-Fluoro-6-methoxyphenylboronic acid
78495-63-3
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
78495-63-3 (2-Fluoro-6-methoxyphenylboronic acid) Related Search:
1of4
