ChemicalBook >> CAS DataBase List >>1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE

1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE

1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE structure

CAS No.

Chemical Name:: 1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE

Synonyms: INHIBITOR BOC-I;Z-L-NHNHCONHNH-LF-BOC;CATHEPSIN K INHIBITOR II;1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE

CBNumber:: CB2358411

Molecular Formula:: C35H51N7O8

Molecular Weight:: 697.82

MDL Number:: MFCD06411402

MOL File:: Mol file

Last updated:2026-01-13 13:16:50

Request For Quotation

1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE Properties

storage temp.	-20°C
solubility	DMSO: 1mg/mL
form	lyophilized solid
color	white
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

WGK Germany	WGK 1
Storage Class	11 - Combustible Solids

1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	INB0002516	1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE 95.00%		5MG	$495.69	2021-12-16	Buy

Product number	Packaging	Price	Buy
INB0002516	5MG	$495.69	Buy

1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE Chemical Properties,Uses,Production

Uses

A cell-permeable peptidyl bis-carbohydrazide compound that acts as a potent, selective, and reversible inhibitor of cathepsin K (K_i = 6 nM). Reported to completely block cathepsin K activity in primary human synovial fibroblast cultures at a concentration of 1 µM. Also shown to inhibit the activity of cathepsin B and papain at higher concentrations (K_i = 510 nM and 1.2 µM, respectively). Does not significantly inhibit cathepsin L.

Biological Activity

Cell permeable: yes', 'Primary Target
cathepsin K', 'Product does not compete with ATP.', 'Reversible: yes', 'Target Ki: 6 nM against cathepsin; 510 nM, 1.2 μM, against cathepsin B and papain, respectively

1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE Suppliers

Global( 2)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Merck KGaA	--	ordercn@merckgroup.com	China	6376	58
EMD Biosciences, Inc.	--	technical@calbiochem.com	United States	6527	66

Supplier	Advantage
Merck KGaA	58
EMD Biosciences, Inc.	66

(1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE)Related Search:

Carbohydrazide

1-(N-BENZYLOXYCARBONYL-LEUCYL)-5-(N-BOC-PHENYLALANYL-LEUCYL)CARBOHYDRAZIDE CATHEPSIN K INHIBITOR II INHIBITOR BOC-I Z-L-NHNHCONHNH-LF-BOC