3-Amino-4-iodopyridine
- CAS No.
- 105752-11-2
- Chemical Name:
- 3-Amino-4-iodopyridine
- Synonyms
- 4-Iodopyridin-3-amine;3-amino-4-Iodopyrdine;Zinc00334520;4-iodopyridin-3-amin;4-Iodo-3-pyridinamine;3-amine-4-iodopyridin;3-Amnio-4-iodopyridine;3-AMINO-4-IODOPYRIDINE;4-IODO-3-AMINOPYRIDINE;3-amine-4-iodopyridine
- CBNumber:
- CB2377814
- Molecular Formula:
- C5H5IN2
- Molecular Weight:
- 220.01
- MDL Number:
- MFCD04971334
- MOL File:
- 105752-11-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 69.2-69.5°C |
|---|---|
| Boiling point | 327.2±27.0 °C(Predicted) |
| Density | 2.055 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | solid |
| pka | 4.79±0.18(Predicted) |
| Appearance | Light yellow to brown Solid |
| Sensitive | Air & Light Sensitive |
| InChI | InChI=1S/C5H5IN2/c6-4-1-2-8-3-5(4)7/h1-3H,7H2 |
| InChIKey | ZJRSKTXMSIVNAU-UHFFFAOYSA-N |
| SMILES | C1=NC=CC(I)=C1N |
| CAS DataBase Reference | 105752-11-2(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22-37/38-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3-Amino-4-iodopyridine price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 736023 | 3-Amino-4-iodopyridine 97% | 105752-11-2 | 500mg | $136 | 2026-04-30 | Buy |
| Usbiological | 280804 | 4-Iodopyridin-3-ylamine Asreported | 105752-11-2 | 500mg | $333 | 2026-06-03 | Buy |
| Usbiological | 280804 | 4-Iodopyridin-3-ylamine Asreported | 105752-11-2 | 1g | $529 | 2026-06-03 | Buy |
| Usbiological | 280804 | 4-Iodopyridin-3-ylamine Asreported | 105752-11-2 | 2g | $726 | 2026-06-03 | Buy |
| Usbiological | 280804 | 4-Iodopyridin-3-ylamine Asreported | 105752-11-2 | 5g | $1303 | 2026-06-03 | Buy |
3-Amino-4-iodopyridine Chemical Properties, Uses, Production
Uses
3-Amino-4-iodopyridine is a heterocyclic derivative and can be used as a pharmaceutical intermediate.
Definition
ChEBI: 3-amino-4-iodopyridine is an aminopyridine that is 3-aminopyridine carrying an additional iodo substituent at postion 4. It has a role as a Saccharomyces cerevisiae metabolite. It is an aminopyridine and an organoiodine compound.
Synthesis
113975-32-9
105752-11-2
General procedure for the synthesis of 3-amino-4-iodopyridine from N-(4-iodo-3-pyridinyl)-2,2-dimethylpropanamide: N-(4-iodo-3-pyridinyl)-2,2-dimethylpropanamide (20.00 g, 65.76 mmol) was placed in a 2 L round-bottomed flask, and 24% sulfuric acid aqueous solution (640 mL) was added. The mixture was carefully heated to 100 °C and kept for 4 hours. The progress of the reaction was monitored by analytical HPLC. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was slowly adjusted to 7-8 with 4 N NaOH solution (~700 mL).Subsequently, saturated sodium bicarbonate solution was added and extracted with dichloromethane (3 x 500 mL). The organic phases were combined and concentrated to give 3-amino-4-iodopyridine (13.3 g, 92% yield).
References
[1] Journal of Medicinal Chemistry, 2007, vol. 50, # 26, p. 6519 - 6534
[2] Patent: WO2006/86609, 2006, A2. Location in patent: Page/Page column 154
[3] Patent: EP1595881, 2005, A1. Location in patent: Page/Page column 57
[4] Journal of Heterocyclic Chemistry, 1994, vol. 31, # 1, p. 11 - 16
[5] Tetrahedron Letters, 2004, vol. 45, # 46, p. 8569 - 8573
3-Amino-4-iodopyridine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| ChemFuture PharmaTech (Jiangsu) Ltd | 5108538618 | suger.wang@chemfuture.com | China | 832 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
View Latest Price from 3-Amino-4-iodopyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 4-Iodo-3-pyridinamine
105752-11-2
|
$1.60-6.60 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-08-20 | 3-Amino-4-iodopyridine
105752-11-2
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2025-04-04 | 3-Amino-4-iodopyridine
105752-11-2
|
1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 4-Iodo-3-pyridinamine
105752-11-2
- $1.60-6.60
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 3-Amino-4-iodopyridine
105752-11-2
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Amino-4-iodopyridine
105752-11-2
- 98%
- Henan Aochuang Chemical Co.,Ltd.
105752-11-2 (3-Amino-4-iodopyridine) Related Search:
1of4
