3-Bromo-5-iodo-pyridin-4-ylamine
- CAS No.
- 902837-39-2
- Chemical Name:
- 3-Bromo-5-iodo-pyridin-4-ylamine
- Synonyms
- 3-bromo-5-iodopyridin-4-amine;3-bromo-5-iodo-4-Pyridinamine;4-AMINO-3-BROMO-5-IODOPYRIDINE;4-PyridinaMine, 3-broMo-5-iodo-;3-Bromo-5-iodo-pyridin-4-ylamine;4-Amino-3-bromo-5-iodopyridine 95+%;3-BROMO-5-IODO-PYRIDIN-4-YLAMINE ISO 9001：2015 REACH
- CBNumber:
- CB7169746
- Molecular Formula:
- C5H4BrIN2
- Molecular Weight:
- 298.91
- MDL Number:
- MFCD07781147
- MOL File:
- 902837-39-2.mol
- MSDS File:
- SDS
| Boiling point | 348.8±42.0 °C(Predicted) |
|---|---|
| Density | 2.426±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 5.19±0.24(Predicted) |
| Appearance | White to off-white Solid |
| Sensitive | Light Sensitive |
| InChI | InChI=1S/C5H4BrIN2/c6-3-1-9-2-4(7)5(3)8/h1-2H,(H2,8,9) |
| InChIKey | OGUAUXDOIHVFPA-UHFFFAOYSA-N |
| SMILES | C1=NC=C(I)C(N)=C1Br |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| HS Code | 2933399990 |
3-Bromo-5-iodo-pyridin-4-ylamine price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS47792 | 3-Bromo-5-iodopyridin-4-amine 95% | 902837-39-2 | 1g | $43 | 2026-06-04 | Buy |
| Activate Scientific | AS47792 | 3-Bromo-5-iodopyridin-4-amine 95% | 902837-39-2 | 5g | $100 | 2026-06-04 | Buy |
| Activate Scientific | AS47792 | 3-Bromo-5-iodopyridin-4-amine 95% | 902837-39-2 | 25g | $331 | 2026-06-04 | Buy |
| Matrix Scientific | 123468 | 4-Amino-3-bromo-5-iodopyridine | 902837-39-2 | 1.00g | $281 | 2026-05-18 | Buy |
| Synthonix | A13423 | 4-Amino-3-bromo-5-iodopyridine 95+% | 902837-39-2 | 5g | $60 | 2026-05-06 | Buy |
3-Bromo-5-iodo-pyridin-4-ylamine Chemical Properties, Uses, Production
Synthesis
13534-98-0
902837-39-2
The general procedure for the synthesis of 3-bromo-5-iodopyridin-4-amine from 4-amino-3-bromopyridine was as follows: a solution was prepared by dissolving potassium iodide (2.88 g, 17.34 mmol) and iodine (2.75 g, 10.84 mmol) in water (21 mL). This solution was slowly added dropwise to a solution in water (10 mL) containing 4-amino-3-bromopyridine (2.5 g, 14.45 mmol) and sodium carbonate (0.919 g, 8.67 mmol). The reaction mixture was stirred under reflux conditions for 20 hours. After completion of the reaction, the mixture was diluted with water and ethyl acetate (EtOAc) and the aqueous and organic layers were separated. The aqueous layer was extracted three times with ethyl acetate and the organic layers were combined. The combined organic layers were washed three times with saturated sodium bicarbonate (NaHCO3) solution and sodium thiosulfate (Na2S2O3) solution sequentially. The organic layer was dried over anhydrous magnesium sulfate (MgSO4), then filtered and the filtrate was concentrated in vacuum. The brown oil obtained was purified by silica gel column chromatography (using a Biotage system with the eluent cyclohexane/ethyl acetate in a ratio of 50:50 gradient to 0:100) to afford the target product 3-bromo-5-iodopyridin-4-amine (951 mg, 22% yield) and the unreacted raw material 4-amino-3-bromopyridine (1.66 g) as a light yellow solid.
References
[1] Journal of Organic Chemistry, 2012, vol. 77, # 11, p. 5006 - 5016
[2] Patent: US2016/16951, 2016, A1. Location in patent: Paragraph 0867; 0868
3-Bromo-5-iodo-pyridin-4-ylamine Preparation Products And Raw materials
3-Bromo-5-iodo-pyridin-4-ylamine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Suzhou Xinkai Bio-Medical Technology Co., Ltd. | 0512-67213637 13952409868 | peter19zhang@163.com | China | 442 | 55 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9510 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
View Latest Price from 3-Bromo-5-iodo-pyridin-4-ylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 3-BROMO-5-IODO-PYRIDIN-4-YLAMINE
902837-39-2
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-13 | 4-Amino-3-Bromo-5-Iodopyridine
902837-39-2
|
1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2019-12-23 | 3-BROMO-5-IODO-PYRIDIN-4-YLAMINE
902837-39-2
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 3-BROMO-5-IODO-PYRIDIN-4-YLAMINE
902837-39-2
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 4-Amino-3-Bromo-5-Iodopyridine
902837-39-2
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 3-BROMO-5-IODO-PYRIDIN-4-YLAMINE
902837-39-2
- $1.00
- 99%
- Career Henan Chemical Co
