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Met-Glu-His-Phe-Arg-Trp-Gly

Met-Glu-His-Phe-Arg-Trp-Gly Structure
Met-Glu-His-Phe-Arg-Trp-Gly structure
CAS No.
4037-01-8
Chemical Name:
Met-Glu-His-Phe-Arg-Trp-Gly
Synonyms
n-acetyl semax amidate;n-acetyl semax;Ac-Met-Glu-His-Phe-Pro-Gly-Pro;MEHFRWG;ACTH (4-10);a-MSH (4-10);ACTH (4-10) a;ACTH (4-10), HUMAN;Met-Glu-His-Phe-Arg-Trp-Gly;L-MET-GLU-HIS-PHE-ARG-TRP-GLY
CBNumber:
CB2378482
Molecular Formula:
C44H59N13O10S
Molecular Weight:
962.09
MDL Number:
MFCD00167482
MOL File:
4037-01-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:50:38
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Met-Glu-His-Phe-Arg-Trp-Gly Properties

Density 1.48±0.1 g/cm3(Predicted)
RTECS MC0596950
storage temp. −20°C
pka 3.32±0.10(Predicted)
form Solid
color White to off-white
Sequence Met-Glu-His-Phe-Arg-Trp-Gly
InChIKey HAAUASBAIUJHAN-LXOXETEGSA-N
SMILES C(C1=CNC2=CC=CC=C12)[C@@H](C(=O)NCC(=O)O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCSC)CC1NC=NC=1)CC1C=CC=CC=1
FDA UNII J48AU3I790

SAFETY

Risk and Safety Statements

WGK Germany  3

Met-Glu-His-Phe-Arg-Trp-Gly price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A0401 Adrenocorticotropic Hormone Fragment 4-10 human, rat ≥97% (HPLC) 4037-01-8 1mg $134 2023-06-20 Buy
Sigma-Aldrich A0401 Adrenocorticotropic Hormone Fragment 4-10 human, rat ≥97% (HPLC) 4037-01-8 5mg $371 2023-01-07 Buy
Biosynth FA108374 ACTH (4-10) trifluoroacetate salt 4037-01-8 25mg $900 2026-06-04 Buy
Biosynth FA108374 ACTH (4-10) trifluoroacetate salt 4037-01-8 10mg $900 2026-06-04 Buy
Biosynth FA108374 ACTH (4-10) trifluoroacetate salt 4037-01-8 5mg $900 2026-06-04 Buy
Product number Packaging Price Buy
A0401 1mg $134 Buy
A0401 5mg $371 Buy
FA108374 25mg $900 Buy
FA108374 10mg $900 Buy
FA108374 5mg $900 Buy

Met-Glu-His-Phe-Arg-Trp-Gly Chemical Properties, Uses, Production

Uses

Adrenocorticotropic Hormone (ACTH) (4-10), human is a melanocortin 4 (MC4R) receptor agonist.

Biological Activity

Adrenocorticotropic Hormone (ACTH) (1-39), rat is a potent melanocortin 4 receptor (MC4R) agonist.

in vitro

Adrenocorticotropic Hormone (ACTH) (4-10), human (ACTH (4-10)) is the core sequence of all melanocortins and binds selectively to MC4-R. In humans, ACTH (4-10) enters the cerebral fluid compartment after intranasal application and leads to a decrease in total body fat after 6 weeks of continuous treatment.

target

Melanocortin 4 receptor

IC 50

MC4R

References

[1] Wellhner P, et al. Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue. Int J Obes (Lond). 2012 May;36(5):703-8. DOI:10.1038/ijo.2011.105

Met-Glu-His-Phe-Arg-Trp-Gly Preparation Products And Raw materials

Raw materials

Preparation Products

Met-Glu-His-Phe-Arg-Trp-Gly Suppliers

Global Suppliers ( 133)
Supplier Tel Email Country ProdList Advantage
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd +86-13393959797 +86-13393959797 master@tsurgex.com China 36 58
Nanjing Typeptide Biotechnology Co.,Ltd. 19961912513; 19941518170 sales@typeptide.com China 4445 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Creative Peptides info@creative-peptides.com United States 6083 56
Nanjing YaoCheng Pharmaceutical Co., Ltd. 025-57043319 15261831516 307514552@qq.com China 298 50
Supplier Advantage
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd 58
Nanjing Typeptide Biotechnology Co.,Ltd. 58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
GL Biochem (Shanghai) Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky（shanghai）International Co.,Ltd. 50
Shanghai T&W Pharmaceutical Co., Ltd. 58
Wuxi Zhongkun Biochemical Technology Co., Ltd. 58
Creative Peptides 56
Nanjing YaoCheng Pharmaceutical Co., Ltd. 50

View Latest Price from Met-Glu-His-Phe-Arg-Trp-Gly manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Acetyl Semax Amidate pictures 2026-08-25 N-Acetyl Semax Amidate
4037-01-8
 1g 99% 500g Xi an Biohorlden Industry Trade Co Ltd
N-Acetyl semax pictures 2026-08-08 N-Acetyl semax
4037-01-8
 1G 99% 1 Shandong Hanjiang Chemical Co., Ltd
N-Acetyl semax pictures 2025-11-27 N-Acetyl semax
4037-01-8
 $201.31-335.51 1g 99% 1 tons TsurgeX Pharmaceutical Technology Co., Ltd.
  • N-Acetyl semax pictures
  • N-Acetyl semax
    4037-01-8
  • $201.31-335.51
  • 99%
  • TsurgeX Pharmaceutical Technology Co., Ltd.

4037-01-8 (Met-Glu-His-Phe-Arg-Trp-Gly) Related Search:

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AC-SER(AC)-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-NH2,N-ACETYL-SER[AC]-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-NH2 BETA-MSH, HUMAN H-ASP-GLU-GLY-PRO-TYR-ARG-MET-GLU-HIS-PHE-ARG-TRP-GLY-SER-PRO-PRO-LYS-ASP-OH,ASP-GLU-GLY-PRO-TYR-ARG-MET-GLU-HIS-PHE-ARG-TRP-GLY-SER-PRO-PRO-LYS-ASP

1of4

H-MET-GLU-HIS-PHE-ARG-TRP-GLY-OH ADRENOCORTICOTROPIC HORMONE FRAGMENT 4-10 ADRENOCORTICOTROPIC HORMONE (4-10) ADRENOCORTICOTROPIC HORMONE (4-10), HUMAN ADRENOCORTICOTROPIC HORMONE HUMAN FRAGMENT 4-10 ACTH (4-10) ACTH (4-10), HUMAN L-MET-GLU-HIS-PHE-ARG-TRP-GLY (5S,8S,11S,14S,17S)-14-((1H-Imidazol-4-yl)methyl)-5-((1H-indol-3-yl)methyl)-17-((S)-2-amino-4-(methylthio)butanamido)-11-benzyl-8-(3-guanidinopropyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaicosane-1,20-dioic acid ACTH (4-10) trifluoroacetate salt H-Met-Glu-His-Phe-Arg-Trp-Gly-OH trifluoroacetate salt Adrenocorticotropic Hormone (ACTH) (4-10) L-Methionyl-L-a-glutamyl-L-histidyl-D-phenylalanyl-N5-(diaminomethylene)-L-ornithyl-L-tryptophylglycine ACTH (4-10),MET-GLU-HIS-PHE-ARG-TRP-GLY MEHFRWG adrenocorticotropic hormone fragment*4-10 human a-MSH (4-10) adrenocorticotropic hormone fragment 4-10 human, rat Adrenocorticotropic Hormone (ACTH) (4-10), human Glycine, L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl- N-acetyl semax amidate ACTH (4-10) Ac-Met-Glu-His-Phe-Pro-Gly-Pro n-acetyl semax amidate n-acetyl semax ACTH (4-10) a Met-Glu-His-Phe-Arg-Trp-Gly 4037-01-8 1265823-54-2 C44H59N13O10S1 C44H59N13O10S C50H65N13O10S Peptides BioChemical Adrenocorticotropic Hormones (ACTH) Amino Acids and Peptides Biochemicals and Reagents Adrenocorticotropic Hormones (ACTH) Peptides and Proteins Peptides for Cell Biology Peptide