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HEMATIN

CAS No.
15489-90-4
Chemical Name:
HEMATIN
Synonyms
heme;haem;HEMATIN;HEMATEIN;Hematins;phenodin;HAEMATIN;ferriheme;ferrihemate;Hematin BR
CBNumber:
CB2390068
Molecular Formula:
C34H31FeN4O5-
Molecular Weight:
631.49
MDL Number:
MFCD00011615
MOL File:
15489-90-4.mol
Last updated:2025-09-17 14:35:14

HEMATIN Properties

Melting point 180 °C
storage temp. 2-8°C
solubility DMF (Slightly), DMSO (Slightly, Heated, Sonicated), Pyridine (Slightly, Heated,
form solid
color Black
biological source Porcine
Merck 14,4635
Stability Light Sensitive
LogP 7.193 (est)
CAS DataBase Reference 15489-90-4
NCI Dictionary of Cancer Terms heme
FDA UNII 0WP180G15G
UNSPSC Code 12352202
NACRES NA.61

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P261-P271
WGK Germany  3
RTECS  NO6725000
HS Code  2934999090
Toxicity LD50 i.v. in rats: 4.32 mg/100 g (Lips)

HEMATIN price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H3281 Hematin porcine 15489-90-4 1g $68.1 2025-07-31 Buy
Sigma-Aldrich H3281 Hematin porcine 15489-90-4 5g $204 2025-07-31 Buy
Sigma-Aldrich H3281 Hematin porcine 15489-90-4 250mg $67.7 2025-07-31 Buy
Sigma-Aldrich H3281 Hematin porcine 15489-90-4 10g $343 2025-07-31 Buy
Apolloscientific BIB6063 Hematin porcine 15489-90-4 1g $87 2021-12-16 Buy
Product number Packaging Price Buy
H3281 1g $68.1 Buy
H3281 5g $204 Buy
H3281 250mg $67.7 Buy
H3281 10g $343 Buy
BIB6063 1g $87 Buy

HEMATIN Chemical Properties,Uses,Production

Description

Produced from red blood cells, Hematin is a bluish-black or brownish pigment compound derived from hemoglobin by removal of the protein part and oxidation of the iron atom from ferrous Fe2+ to the ferric Fe3+ state, which does not combine with oxygen. It is effective to inhibit the synthesis of porphyrin and, at the same time, stimulate the synthesis of globin. It involves in the formation of cytochromes and peroxidases in the cell. Hematin is also a pharmaceutical used in the treatment of porphyria, which can be administered intravenously to halt the attack of acute porphyria. It functions in the liver to accelerate the production of heme and thus preventing the further accumulation of heme precursors, porphyrins, which is effective to alleviate the symptoms of porphyria.

References

https://en.wikipedia.org/wiki/Haematin
http://house.wikia.com/wiki/Hematin
https://en.oxforddictionaries.com/definition/us/hematin
http://medical-dictionary.thefreedictionary.com/hematin

Chemical Properties

Dark crystals with metalic luster

Uses

Indicator, biological stain.

Uses

Hematin was used in a study to test in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. It was also used in a study to test in-vitro bacterial identification using fluorescence spectroscopy with an optical fiber system.

Definition

The hydroxide of heme. Not to be confused with hematein.

Biological Activity

Hematin is a hydroxide of heme. It may be used to tre at acute porphyric attacks. Hematin suppresses the hepatic aminolevulinic acid (ALA) function and replenishes cytochrome action by restoring the endogenous heme deficit. Early administration of hematin can prevent irreversible neuronal damage induced due to metabolic disorders.

Purification Methods

Crystallise it from pyridine. Dry it at 40o in vacuo.[Beilstein 26 III/IV 3047.]

HEMATIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 143)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365 mina@chuanghaibio.com China 18126 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32432 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 20424 58
Wuhan wingroup Pharmaceutical Co., Ltd
+86-13296627870; +8613296627870 info@whwingroup.com China 695 58
ShanDong Look Chemical Co.,Ltd.
+8617653113219 sales01@sdlookchemical.com China 2768 58
Hebei Fengjia New Material Co., Ltd
+86-0311-87836622 +86-18712993135 sales01@tairunfaz.com China 8051 58
Hebei Miaoyin Technology Co.,Ltd
+852-852-95427495 +85295427495 kathy@hbyinsheng.com China 3512 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 43339 58

View Lastest Price from HEMATIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Hematin pictures 2025-09-17 Hematin
15489-90-4
US $42.00 / mg 99.25% 10g TargetMol Chemicals Inc.
HEMATIN pictures 2025-06-27 HEMATIN
15489-90-4
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
HEMATIN pictures 2025-06-20 HEMATIN
15489-90-4
US $70.00-18.00 / kg 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
  • Hematin pictures
  • Hematin
    15489-90-4
  • US $42.00 / mg
  • 99.25%
  • TargetMol Chemicals Inc.
  • HEMATIN pictures
  • HEMATIN
    15489-90-4
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • HEMATIN pictures
  • HEMATIN
    15489-90-4
  • US $70.00-18.00 / kg
  • 0.99
  • Hebei Yanxi Chemical Co., Ltd.
2-))-hydroxy- ferrihemate ferriheme ferrihemehydroxide ferrihemicacid HEMATEIN HEMATIN PORCINE HYDROXYHEMIN dihydrogen hydroxy[3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]ferrate(2-) heme HEMATIN FROM PORCINE Ferrate(2-), 7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-.kappa.N21,.kappa.N22,.kappa.N23,.kappa.N24hydroxy-, dihydrogen, (SP-5-13)- haem dihydrogen hydroxy[3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24]ferrate(2-) [Dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-)]hydroxyiron Hematins Ferrate(2-),[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-kN21,kN22,kN23,kN24]hydroxy-, hydrogen (1:2),(SP-5-13)- ferriporphyrinhydroxide ferriprotoporphyrinbasic ferriprotoporphyrinixhydroxide hydroxy(dihydrogenprotoporphyrinix-ato(2-))iron iron,(dihydrogen3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato( phenodin protohematin BOVINE HEMIN HAEMATIN HEMATIN Hematin BR dihydrogen hydroxy[3,8,13,17-tetramethyl-7,12-divinyl-21H,23... Hematin, Iron-containing porphyrin 0WP180G15G 15489-90-4 Hematin Dihydrogen hydroxy(3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24)ferrate(2-) Iron, (dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipropionato(2-))-hydroxy- Bovine hemin EINECS 239-518-9 Ferrihemate Ferriheme Ferriheme hydroxide Ferrihemic acid Ferriporphyrin hydroxide Ferriprotoporphyrin basic Ferriprotoporphyrin IX hydroxide Hydroxy(dihydrogen protoporphyrin IX-ato(2-))iron Hydroxyhemin Phenodin Protohematin UNII-0WP180G15G 0WP180G15G 15489-90-4 Hematin Dihydrogen hydroxy(3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24)ferrate(2-) Iron, (dihydrogen 3,7,12,17-tetramethyl-8,13- 0WP180G15G 15489-90-4 Hematin Dihydrogen hydroxy(3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionato(4-)-N21,N22,N23,N24)ferrate(2-) Iron, (dihydrogen 3,7,12,17-tetramethyl-8,13- 15489-90-4 C34H33N4O5Fe C34H33FeN4O5 C34H32FeN4O4FeOH C34H31FeN4O52H BioChemical Biochemicals and Reagents Application Index Enzymes, Inhibitors, and Substrates Serum Proteins and Related Enzymes Serum Proteins HematinApplication Index Plasma&Blood Proteins Plasma, Blood, and Related Proteins and Reagents Serum Proteins Serum Proteins and Related Enzymes