HEMATIN
- CAS No.
- 15489-90-4
- Chemical Name:
- HEMATIN
- Synonyms
- heme;haem;HEMATIN;HEMATEIN;Hematins;phenodin;HAEMATIN;ferriheme;ferrihemate;Hematin BR
- CBNumber:
- CB2390068
- Molecular Formula:
- C34H31FeN4O5-
- Molecular Weight:
- 631.49
- MDL Number:
- MFCD00011615
- MOL File:
- 15489-90-4.mol
Melting point | 180 °C |
---|---|
storage temp. | 2-8°C |
solubility | DMF (Slightly), DMSO (Slightly, Heated, Sonicated), Pyridine (Slightly, Heated, |
form | solid |
color | Black |
biological source | Porcine |
Merck | 14,4635 |
Stability | Light Sensitive |
LogP | 7.193 (est) |
CAS DataBase Reference | 15489-90-4 |
NCI Dictionary of Cancer Terms | heme |
FDA UNII | 0WP180G15G |
UNSPSC Code | 12352202 |
NACRES | NA.61 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P280-P261-P271 |
WGK Germany | 3 |
RTECS | NO6725000 |
HS Code | 2934999090 |
Toxicity | LD50 i.v. in rats: 4.32 mg/100 g (Lips) |
HEMATIN price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | H3281 | Hematin porcine | 15489-90-4 | 1g | $68.1 | 2025-07-31 | Buy |
Sigma-Aldrich | H3281 | Hematin porcine | 15489-90-4 | 5g | $204 | 2025-07-31 | Buy |
Sigma-Aldrich | H3281 | Hematin porcine | 15489-90-4 | 250mg | $67.7 | 2025-07-31 | Buy |
Sigma-Aldrich | H3281 | Hematin porcine | 15489-90-4 | 10g | $343 | 2025-07-31 | Buy |
Apolloscientific | BIB6063 | Hematin porcine | 15489-90-4 | 1g | $87 | 2021-12-16 | Buy |
HEMATIN Chemical Properties,Uses,Production
Description
Produced from red blood cells, Hematin is a bluish-black or brownish pigment compound derived from hemoglobin by removal of the protein part and oxidation of the iron atom from ferrous Fe2+ to the ferric Fe3+ state, which does not combine with oxygen. It is effective to inhibit the synthesis of porphyrin and, at the same time, stimulate the synthesis of globin. It involves in the formation of cytochromes and peroxidases in the cell. Hematin is also a pharmaceutical used in the treatment of porphyria, which can be administered intravenously to halt the attack of acute porphyria. It functions in the liver to accelerate the production of heme and thus preventing the further accumulation of heme precursors, porphyrins, which is effective to alleviate the symptoms of porphyria.
References
https://en.wikipedia.org/wiki/Haematin
http://house.wikia.com/wiki/Hematin
https://en.oxforddictionaries.com/definition/us/hematin
http://medical-dictionary.thefreedictionary.com/hematin
Chemical Properties
Dark crystals with metalic luster
Uses
Indicator, biological stain.
Uses
Hematin was used in a study to test in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. It was also used in a study to test in-vitro bacterial identification using fluorescence spectroscopy with an optical fiber system.
Definition
The hydroxide of heme. Not to be confused with hematein.
Biological Activity
Hematin is a hydroxide of heme. It may be used to tre at acute porphyric attacks. Hematin suppresses the hepatic aminolevulinic acid (ALA) function and replenishes cytochrome action by restoring the endogenous heme deficit. Early administration of hematin can prevent irreversible neuronal damage induced due to metabolic disorders.
Purification Methods
Crystallise it from pyridine. Dry it at 40o in vacuo.[Beilstein 26 III/IV 3047.]
HEMATIN Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32432 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20424 | 58 |
Wuhan wingroup Pharmaceutical Co., Ltd | +86-13296627870; +8613296627870 | info@whwingroup.com | China | 695 | 58 |
ShanDong Look Chemical Co.,Ltd. | +8617653113219 | sales01@sdlookchemical.com | China | 2768 | 58 |
Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
Hebei Miaoyin Technology Co.,Ltd | +852-852-95427495 +85295427495 | kathy@hbyinsheng.com | China | 3512 | 58 |
HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
View Lastest Price from HEMATIN manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2025-09-17 | Hematin
15489-90-4
|
US $42.00 / mg | 99.25% | 10g | TargetMol Chemicals Inc. | ||
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2025-06-27 | HEMATIN
15489-90-4
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
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2025-06-20 | HEMATIN
15489-90-4
|
US $70.00-18.00 / kg | 1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. |
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