METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE
- CAS No.
- 81452-54-2
- Chemical Name:
- METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE
- Synonyms
- RARECHEM AL BF 0178;3-Methylthiophene-2-Cabroxylate;3-methylthiophene-2-carboxylate;Methyl 3-methylthienyl-2-carboxylate;Eethyl3-methylthiophene-2-carboxylate;METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE;Methyl 3-Methylthiophene-2-carboxylate >Methyl 3-methylthiophene-2-carboxylate ,99%;3-Methylthiophen-2-carboxylic acid methyl ester;3-methyl-2-thiophenecarboxylic acid methyl ester
- CBNumber:
- CB2390952
- Molecular Formula:
- C7H8O2S
- Molecular Weight:
- 156.2
- MDL Number:
- MFCD00234332
- MOL File:
- 81452-54-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 216-217°C |
|---|---|
| Density | 1.173±0.06 g/cm3(Predicted) |
| refractive index | 1.5168 |
| Flash point | 216-217°C |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | clear liquid |
| color | Colorless to Light yellow |
| BRN | 116836 |
| InChI | InChI=1S/C7H8O2S/c1-5-3-4-10-6(5)7(8)9-2/h3-4H,1-2H3 |
| InChIKey | BRWROFVPMUPMJQ-UHFFFAOYSA-N |
| SMILES | C1(C(OC)=O)SC=CC=1C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227 | |||||||||
| Precautionary statements | P210-P280-P403+P235-P501 | |||||||||
| Safety Statements | 23-24/25 | |||||||||
| HS Code | 29151300 | |||||||||
| NFPA 704 |
|
METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2662 | Methyl 3-Methylthiophene-2-carboxylate >97.0%(GC) | 81452-54-2 | 1g | $22 | 2026-04-30 | Buy |
| TCI Chemical | M2662 | Methyl 3-Methylthiophene-2-carboxylate >97.0%(GC) | 81452-54-2 | 5g | $63 | 2026-04-30 | Buy |
| AstaTech | 64772 | METHYL 3-METHYL-THIOPHENE-2-CARBOXYLATE 97% | 81452-54-2 | 1G | $30 | 2026-04-30 | Buy |
| Apolloscientific | OR953363 | Methyl 3-methylthiophene-2-carboxylate 98% | 81452-54-2 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR953363 | Methyl 3-methylthiophene-2-carboxylate 98% | 81452-54-2 | 25g | $43 | 2026-06-04 | Buy |
METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE Chemical Properties,Uses,Production
Chemical Properties
Colorless liquid
Synthesis
67-56-1
23806-24-8
81452-54-2
Step 1: Synthesis of methyl 3-methylthiophene-2-carboxylate: 3-methylthiophene-2-carboxylic acid (15 g, 105 mmol, 1.0 eq.) was dissolved in methanol (150 mL) and concentrated sulfuric acid (7.5 mL) was added slowly and dropwise. The reaction mixture was heated to reflux for 12 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in ethyl acetate (200 mL) and washed sequentially with water (2 x 50 mL), saturated aqueous sodium bicarbonate solution (2 x 50 mL) and brine (50 mL). The organic phase was dried with anhydrous sodium sulfate, filtered, and the filtrate was concentrated under reduced pressure to afford 20 g (97% yield) of methyl 3-methylthiophene-2-carboxylate as an oil. The product was confirmed by 1H NMR (400 MHz, CDCl3): δ 7.38 (d, J=5.0 Hz, 1H), 6.91 (d, J=5.0 Hz, 1H), 3.85 (s, 3H), 2.55 (s, 3H); ESI-MS m/z 157 ([M+H]+).
References
[1] Patent: WO2012/56478, 2012, A1. Location in patent: Page/Page column 75-76
[2] Patent: WO2007/124546, 2007, A1. Location in patent: Page/Page column 58
[3] Patent: WO2014/64131, 2014, A2. Location in patent: Page/Page column 114; 115
[4] Patent: WO2014/76104, 2014, A1. Location in patent: Page/Page column 79-80
[5] Journal of Medicinal Chemistry, 1995, vol. 38, # 24, p. 4806 - 4820
METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| New Energy Chemicals | 0515-82159099 13770142076 | info@njuchem.com | China | 251 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Lastest Price from METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | Methyl 3-methylthiophene-2-carboxylate
81452-54-2
|
$47.00-679.00 | 25g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
 |
2026-08-20 | METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE
81452-54-2
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2026-03-20 | METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE
81452-54-2
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Methyl 3-methylthiophene-2-carboxylate
81452-54-2
- $47.00-679.00
- 0.98
- Shanghai UCHEM Inc.
-
- METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE
81452-54-2
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- METHYL 3-METHYLTHIOPHENE-2-CARBOXYLATE
81452-54-2
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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