Elastase (human leucocytes)
- CAS No.
- 9004-06-2
- Chemical Name:
- Elastase (human leucocytes)
- Synonyms
- elastase from human leukocytes;ELA2;ELANE;elaszym;Eiastase;Elastase-2;e.c.3.4.4.7;Elastase ES;EC 3.4.21.37;EC 3.4.21.36
- CBNumber:
- CB2398822
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00130997
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | -20°C |
|---|---|
| form | lyophilized powder |
| color | White to off-white |
| biological source | rabbit |
| Specific Activity | ≥50units/mg protein (Bradford) |
| CAS DataBase Reference | 9004-06-2 |
| EWG's Food Scores | 1 |
| FDA UNII | U2974059LF |
| EPA Substance Registry System | Elastase (9004-06-2) |
| UNSPSC Code | 12352204 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H334-H335 |
| Precautionary statements | P261-P264-P271-P302+P352-P304+P340+P312-P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | B |
| WGK Germany | 3 |
| F | 3-10 |
| TSCA | TSCA listed |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Resp. Sens. 1 Skin Irrit. 2 STOT SE 3 |
Elastase (human leucocytes) price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB1305716 | ANTI-NEUTROPHIL ELASTASE(N-TERMINAL) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 9004-06-2 | 400μl | $532 | 2026-04-30 | Buy |
| Sigma-Aldrich | E8140 | Elastase from human leukocytes lyophilized powder, ≥50?units/mg protein (Bradford) | 9004-06-2 | 1unit | $251 | 2026-04-30 | Buy |
| Sigma-Aldrich | 324681 | Elastase, Human Neutrophil Elastase, Human Neutrophil, CAS 9004-06-2, is a serine protease that degrades elastin, collagen, and proteoglycans | 9004-06-2 | 50μg | $349 | 2026-04-30 | Buy |
| Sigma-Aldrich | 324681 | Elastase, Human Neutrophil Elastase, Human Neutrophil, CAS 9004-06-2, is a serine protease that degrades elastin, collagen, and proteoglycans | 9004-06-2 | 100μg | $591 | 2026-04-30 | Buy |
| Usbiological | 552903 | ELANE Purified | 100ul | $722 | 2026-06-03 | Buy |
Elastase (human leucocytes) Chemical Properties,Uses,Production
Chemical Properties
Elastase is white or light gray crystalline powder. It is soluble in water, stable at ph4-10.5 and 20C, and can be stored for 3-12 months at 60C. Compound elastase is a white ointment containing elastase and Neomycin sulfate.
Uses
Elastase from human leukocytes has been used:
- to measure serum elastase activity
- in proteolytic digestion of fibronectin and salivary glands
- in neutrophil elastase (NE) activity assay
- cell-free NE digestion of E-cadherin
- scratch wound assay
- in a study that determined that fragments of Nle3-angiotensin(1-7) accelerate healing in dermal models
General Description
Elastase is a proteolytic enzyme. It is a member of the subgroup named, peptidyl peptide hydrolases. It is a major anatomic constituent of arteries. It is mainly found in the pancreas and pancreatic juice of various birds and mammals. It is also present in human serum, granulocytes and erythrocytes.
Biochem/physiol Actions
Elastase enzyme is capable of releasing soluble peptides from insoluble elastin fibers with the help of a proteolytic process. It can stimulate disintegration of the axoneme with the help of adenosine triphosphate (ATP). Unlike pancreatic elastase the leukocyte enzyme has a preferential cleavage for the carboxyl side of valine, but will also cleave to a lesser extent after alanine. Natural substrates include elastin, cartilage proteoglycans, collagen types I, II, II and IV, and fibronectin.
Elastase (human leucocytes) Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Greek Shandong Pharmaceutical Co., Ltd. | -- | China | 3 | 60 | |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Wuhan Fortuna Chemical Co., Ltd | 027-59207852 13308628970 | buy@fortunachem.com | China | 2698 | 58 |
| Nanjing Dulai Biotechnology Co., Ltd. | 025-84699383-8003;025-846993838003-8003 18013301590 | njduly@126.com | China | 3293 | 55 |
| Hubei XinyuanShun Chemical Co., Ltd. | 13971561712, 13995564702, 027-50664929 | hbeixys2001@163.com | China | 3110 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Raw material medicin reagent co.,Ltd | sales@njromanme.com | China | 4511 | 58 | |
| Wuhan Runzeweiye Technology Co., Ltd. | 15172337137 15172337137; | 940329747@qq.com | China | 339 | 55 |
| Wuhan FengyaoTonghui Chemical Products Co., Ltd. | 027-87466105 15377573527 | 2678564200@qq.com | China | 17968 | 58 |
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