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3-[Bis-(2-methoxycarbonyl-ethyl)-phosphanyl]-propionic acid methyl ester

CAS No.
29269-17-8
Chemical Name:
3-[Bis-(2-methoxycarbonyl-ethyl)-phosphanyl]-propionic acid methyl ester
Synonyms
TRI(2-METHOXYCARBONYLETHYL)PHOSPHINE;Trimethyl3,3',3''-phosphinetriyltripropanoate;Trimethyl 3,3',3''-phosphineTriylTripropanoate;Propanoic acid, 3,3',3''-phosphinidynetris-, 1,1',1''-trimethyl ester;3-[Bis-(2-methoxycarbonyl-ethyl)-phosphanyl]-propionic acid methyl ester;Propanoicacid,3,3',3''-phosphinidynetriChemicalbooks-,1,1',1''-trimethylester
CBNumber:
CB2443593
Molecular Formula:
C12H21O6P
Molecular Weight:
292.27
MDL Number:
MFCD07369992
MOL File:
29269-17-8.mol
MSDS File:
SDS
Last updated:2026-09-12 18:51:18

3-[Bis-(2-methoxycarbonyl-ethyl)-phosphanyl]-propionic acid methyl ester Properties

Boiling point 365.4±37.0 °C(Predicted)
storage temp. Inert atmosphere,Room Temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P337+P313-P305+P351+P338
HS Code  2931499090

3-[Bis-(2-methoxycarbonyl-ethyl)-phosphanyl]-propionic acid methyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR906045 Tri(2-methoxycarbonylethyl)phosphine 97% 29269-17-8 250mg $146 2026-06-04 Buy
Apolloscientific OR906045 Tri(2-methoxycarbonylethyl)phosphine 97% 29269-17-8 1g $434 2026-06-04 Buy
Synthonix T56296 Trimethyl 3,3',3''-phosphinetriyltripropanoate 95% 29269-17-8 100mg $250 2026-05-06 Buy
Synthonix T56296 Trimethyl 3,3',3''-phosphinetriyltripropanoate 95% 29269-17-8 1g $420 2026-05-06 Buy
Synthonix T56296 Trimethyl 3,3',3''-phosphinetriyltripropanoate 95% 29269-17-8 250mg $750 2026-05-06 Buy
Product number Packaging Price Buy
OR906045 250mg $146 Buy
OR906045 1g $434 Buy
T56296 100mg $250 Buy
T56296 1g $420 Buy
T56296 250mg $750 Buy

3-[Bis-(2-methoxycarbonyl-ethyl)-phosphanyl]-propionic acid methyl ester Chemical Properties,Uses,Production

Synthesis

Methanol

67-56-1

Tris(2-carboxyethyl)phosphine hydrochloride

51805-45-9

3-[BIS-(2-METHOXYCARBONYL-ETHYL)-PHOSPHANYL]-PROPIONIC ACID METHYL ESTER

29269-17-8

General procedure for the synthesis of trimethyl 3,3',3''-phosphono-tripropionate from methanol and tris(2-carboxyethyl)phosphine hydrochloride: tris(2-carboxyethyl)phosphine hydrochloride (TCEP) (7.0 g, 24.42 mmol) was co-evaporated with ethanol (EtOH) (2 × 100 mL) and subsequently dissolved in methanol (CH3OH) (200 mL) at 4 °C . Thionyl chloride (SOCl2) (9.0 mL, 122.29 mmol) was slowly added to this solution. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was concentrated and dried under vacuum to afford trimethyl 3,3',3''-phosphonyl tripropionate (7.0 g, 98% yield). The product was confirmed by electrospray ionization mass spectrometry (ESI MS) with an observed m/z of 293.2 (M+H)+.

References

[1] Patent: WO2015/28850, 2015, A1. Location in patent: Page/Page column 81

3-[Bis-(2-methoxycarbonyl-ethyl)-phosphanyl]-propionic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

3-[Bis-(2-methoxycarbonyl-ethyl)-phosphanyl]-propionic acid methyl ester Suppliers

Global( 31)Suppliers
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J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
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Propanoic acid, 3,3',3''-phosphinidynetris-, 1,1',1''-trimethyl ester Trimethyl 3,3',3''-phosphineTriylTripropanoate TRI(2-METHOXYCARBONYLETHYL)PHOSPHINE Propanoicacid,3,3',3''-phosphinidynetriChemicalbooks-,1,1',1''-trimethylester Trimethyl3,3',3''-phosphinetriyltripropanoate 3-[Bis-(2-methoxycarbonyl-ethyl)-phosphanyl]-propionic acid methyl ester 29269-17-8 C12H21O6P C12H22O6PCl