ChemicalBook >> CAS DataBase List >>DAGO

DAGO

DAGO structure

CAS No.: 78123-71-4

Chemical Name:: DAGO

Synonyms: DAMGO;DAGO;Dagol;Damge;DAMPGO;RX-783006;NIH 10891;DAMGO, 10 mM in DMSO;M.W. 513.59 C26H35N5O6;Tyr-D-Ala-Gly-MePhe-Gly-ol

CBNumber:: CB2459705

Molecular Formula:: C26H35N5O6

Molecular Weight:: 513.59

MDL Number:: MFCD00076432

MOL File:: 78123-71-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-17 09:03:53

Request For Quotation

DAGO Properties

Boiling point	922.7±65.0 °C(Predicted)
Density	1.271±0.06 g/cm3(Predicted)
storage temp.	-15°C
solubility	≥40.7 mg/mL in EtOH; ≥40.7 mg/mL in H2O; ≥42.2 mg/mL in DMSO
form	solid
pka	9.97±0.15(Predicted)
color	White
Water Solubility	Soluble in water (4 mM)
Sequence	H-Tyr-D-Ala-Gly-NMe-Phe-Gly-ol
Stability	Hygroscopic
InChIKey	HPZJMUBDEAMBFI-RZPISPKSNA-N
SMILES	[C@H](C(=O)NCCO)(N(C)C(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)CC1C=CC=CC=1 \|&1:0,15,20,r\|

DAGO price More Price(45)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	21553	DAMGO ≥98%	78123-71-4	1mg	$35	2021-12-16	Buy
Cayman Chemical	21553	DAMGO ≥98%	78123-71-4	5mg	$96	2021-12-16	Buy
Usbiological	255099	DAMGO ≥97%(HPLC)	78123-71-4	1mg	$325	2026-06-03	Buy
TRC	TRC-D134600-5MG	DAMGO		5mg	$351	2026-06-03	Buy
TRC	TRC-D134600-1MG	DAMGO		1mg	$109	2026-06-03	Buy

Product number	Packaging	Price	Buy
21553	1mg	$35	Buy
21553	5mg	$96	Buy
255099	1mg	$325	Buy
TRC-D134600-5MG	5mg	$351	Buy
TRC-D134600-1MG	1mg	$109	Buy

DAGO Chemical Properties,Uses,Production

Uses

DAMGO is an opioid receptor agonist (1,2). DAMGO can be used to investigate the analgesic mechanism of opioids. It has been shown that DAMGO can modulate the two-pore domain K(+) channels in the substantia gelatinosa neurons (3).

Definition

ChEBI: (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin is a peptide.

Biological Activity

Highly selective peptide agonist for the μ opioid receptor.

in vivo

DAMGO (i.v., 0.5-2 mg/kg) can produce significant anti-injury effects on injured paws of male Sprague-Dawley rats weighing 200-225 g in a dose-dependent manner, producing an effective and long-lasting analgesic effect^[4].

IC 50

μ Opioid Receptor/MOR

storage

-20°C (desiccate)

DAGO Preparation Products And Raw materials

Raw materials

Preparation Products

DAGO Suppliers

Global( 150)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
TargetMol Chemicals Inc.	021-021-33632979 15002134094	marketing@targetmol.com	China	7993	58
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632;	sales@reading-chemicals.com	China	15165	58
Shanghai Macklin Biochemical Co.,Ltd.	15221275939 15221275939	shenlinxing@macklin.cn	China	15775	55
Creative Peptides		info@creative-peptides.com	United States	6083	56
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
ShangHai Biochempartner Co.,Ltd	177-54423994 17754423994	2853530910@QQ.com	China	8000	62
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9699	58
Nanjing Peptide Biotech Ltd.	025-58361106-805 15951641583	zhao.xu@njpeptide.com	China	9976	55

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
GL Biochem (Shanghai) Ltd	64
TargetMol Chemicals Inc.	58
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58
Shanghai Macklin Biochemical Co.,Ltd.	55
Creative Peptides	56
Shanghai YuanYe Biotechnology Co., Ltd.	60
ShangHai Biochempartner Co.,Ltd	62
Shanghai Chaolan Chemical Technology Center	58
Nanjing Peptide Biotech Ltd.	55

View Lastest Price from DAGO manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-16	DAMGO 78123-71-4	$43.00-79.00		99.94%	10g	TargetMol Chemicals Inc.
2026-07-07	DAMGO 78123-71-4	$800.00-1500.00	1G	98%HPLC	500 G	Shaanxi Dideu Medichem Co. Ltd
2024-03-31	DAGO 78123-71-4	$20.00-30.00	1kg	99%	2000000	Shanghai Chinqesen Biotechnology Co., Ltd.

DAMGO
78123-71-4
$43.00-79.00
99.94%
TargetMol Chemicals Inc.

DAMGO
78123-71-4
$800.00-1500.00
98%HPLC
Shaanxi Dideu Medichem Co. Ltd

DAGO
78123-71-4
$20.00-30.00
99%
Shanghai Chinqesen Biotechnology Co., Ltd.

DAGO Spectrum

DAGO(78123-71-4)MS DAGO(78123-71-4)¹HNMR

78123-71-4(DAGO)Related Search:

DAMGO [TYROSYL-3,5-3H, (DAGO)] ([125I]-TYR)-DAGO guanyl-DAMME DAGO [TYROSYL-3,5-3H] DAGO ACETATE SALT,DAGO, DAMGO, Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol

FK 33-824 [3,5-DIIODO-TYR1]-DAGO,(3,5-DIIODO-TYR1)-DAGO ACOH,(3,5-DIIODO-TYR1)-DAGO ACETATE SALT,3,5-Diiodo-Tyr-D-Ala-Gly-N-Methyl-Phe-Gly-ol, [3,5-Diodo-Tyr1]-DAGO DAGO

1of2

Tyr-D-Ala-Gly-MePhe-Gly-ol Tyr-D-Ala-Gly-MePhe-NH-(CH2)2OH Tyr-D-Ala-Gly-N-methylphenylalanine-glycinol TYR-D-ALA-GLY-N-ME-PHE-GLY-OL TYR-D-ALA-GLY-N-METHYL-PHE-GLY-OL DAGO (D-ALA2,N-ME-PHE4,GLYCINOL5)-ENKEPHALIN [D-ALA2, NME-PHE4, GLY-OL5]-ENKEPHALIN [D-ALA2, N-ME-PHE4, GLY-OL]-ENKEPHALIN [D-ALA2,N-METHYL-PHE4,GLY-OL5]-ENKEPHALIN H-TYR-D-ALA-GLY-N-ME-PHE-GLYCINOL ala(2)-mephe(4)-gly-ol(5)-enkephali DAMGO >98% SYNTHETIC (D-ALA2,N-ME-PHE4,G LY H-Tyr-D-Ala-Gly-N-Me-Phe-Gly-OL M.W. 513.59 C26H35N5O6 L-Tyr-D-Ala-Gly-N-Methyl-L-Phe-Gly-OH [D-Ala2,MePhe4,Gly-ol5]enkephalin L-Tyr-D-Ala-Gly-N-Methyl-L-Phe-N-(2-hydroxyethyl)-NH2 RX-783006 2-Ala-4-mephe-5-Gly-enkephalin Ala(2)-mephe(4)-Gly-ol(5) enkephalin Dagol Damge Enkephalin, Ala(2)-mephe(4)-Gly-ol(5)- [D-Ala(2),N-methyl-Phe(4),Gly(5)-ol]-enkephalin 3: PN: WO2009046859 PAGE: 98 claimed protein DAMPGO H-Tyr-D-Ala(Me)Phe-NH-CH2-OH L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-L-phenylalaninamide NIH 10891 PN: US20030176421 PAGE: 54-55 claimed protein Tyr-D-Ala-Gly-(methyl)Phe-Gly-ol (D-Ala2,N-Me-Phe4,Gly5-ol)enkephalin L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nα-methyl- DAMGO, mu opioid receptor agonist DAMGO, 10 mM in DMSO L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nα-methyl-L-phenylalaninamide DAMGO (2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-1-(2-hydroxyethylamino)-1-oxo-3-phenylpropan-2-yl]-methylamino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide 78123-71-4 C26H35N5O6 Peptide Opioid receptor and opioid-like receptor