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MM-589 TFA salt

CAS No.
2097887-21-1
Chemical Name:
MM-589 TFA salt
Synonyms
MM-589 (TFA);MM-589 TFA salt;MM589 TFA,MM 589 TFA
CBNumber:
CB24675387
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD32689433
MOL File:
Mol file
MSDS File:
SDS
Last updated:2024-01-25 15:49:39

MM-589 TFA salt Properties

storage temp. -20°C, away from moisture
solubility DMSO : 25 mg/mL (36.40 mM; ultrasonic and warming and heat to 60°C)

MM-589 TFA salt price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth XID88721 MM-589 TFA 2097887-21-1 1mg $1821.52 2026-06-05 Buy
ChemScene CS-0069689 MM-589TFA 98.76% 2097887-21-1 1mg $1200 2021-12-16 Buy
ChemScene CS-0069689 MM-589TFA 98.76% 2097887-21-1 2mg $1800 2021-12-16 Buy
Product number Packaging Price Buy
XID88721 1mg $1821.52 Buy
CS-0069689 1mg $1200 Buy
CS-0069689 2mg $1800 Buy

MM-589 TFA salt Chemical Properties, Uses, Production

Biological Activity

MM-589 TFA is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interactions. MM-MM-589 TFA binds WDR5 with an IC50 of 0.90 nM. IC50 for inhibition of MLL H3K4 methyltransferase activity is 12.7 nM.

in vitro

MM-589 TFA (0.01-10 μM, 4 days or 7 days) potently and selectively inhibits cell growth in human leukemia cell lines harboring MLL translocations.

Cell Viability Assay < table class="zh_use_1"> < tr>

Cell Line: MV4-11 and MOLM-13 cells
Concentration: 0.01, 0.1, 1, 10 μM
Incubation Time: 4 days or 7 days
Result: Potently inhibited MV4-11 and MOLM-13 cell growth with IC 50 s of 0.25 and 0.21 μM, respectively. Had much weaker activity in the inhibition of cell growth of the HL-60 cell line with an IC 50 of 8.6 μM.

target

IC50: 0.90 nM (WDR5), 12.7 nM (HMT)

Ki: <1 nM (WDR5)

MM-589 TFA salt Preparation Products And Raw materials

Raw materials

Preparation Products

MM-589 TFA salt Suppliers

Global Suppliers ( 24)
Supplier Tel Email Country ProdList Advantage
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Nanjing Leon Biological Technology Co., Ltd. 025-84523390 -127; 17705183659 sales@njleonbiotech.com China 5501 55
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 15967184799 Eric@peptidego.com China 7872 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 sales@sarms4muscle.com China 10378 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5123 58
Wuxi Helen Biotechnology Co., Ltd., 0510-85629785 18013409632 sales@reading-chemicals.com China 14072 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4565 58
Hangzhou Go Top Peptide Biotech 0571-88211921 17357109671 sales3@gotopbio.com China 2988 58

View Latest Price from MM-589 TFA salt manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
MM-589 TFA  pictures 2024-04-02 MM-589 TFA
2097887-21-1
$2.00 1kg 99% 200kg Wuhan Xinhao Biotechnology Co., Ltd
  • MM-589 TFA  pictures
  • MM-589 TFA
    2097887-21-1
  • $2.00
  • 99%
  • Wuhan Xinhao Biotechnology Co., Ltd
MM-589 TFA salt MM-589 (TFA) MM589 TFA,MM 589 TFA 2097887-21-1