ChemicalBook >> CAS DataBase List >>BAY-545
BAY-545
- CAS No.
- 1699717-32-2
- Chemical Name:
- BAY-545
- Synonyms
- BAY-545;BAY-545, 10 mM in DMSO;BAY-545;BAY545;BAY 545;1699717-32-2;Inhibitor,BAY 545,BAY545,Adenosine Receptor,BAY-545,P1 receptor,inhibit;3-Ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione;Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 3-ethyl-6-[(4-hydroxy-1-piperidinyl)carbonyl]-5-methyl-1-(3,3,3-trifluoropropyl)-
- CBNumber:
- CB24819491
- Molecular Formula:
- C18H22F3N3O4S
- Molecular Weight:
- 433.45
- MDL Number:
- MFCD32062683
- MOL File:
- 1699717-32-2.mol
Last updated:2025-04-28 21:36:36
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
BAY-545 price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28420 | BAY-545 | 1699717-32-2 | 1mg | $242 | 2024-03-01 | Buy |
| Cayman Chemical | 28420 | BAY-545 | 1699717-32-2 | 5mg | $1028 | 2024-03-01 | Buy |
| Biorbyt Ltd | orb611940 | BAY-545 >98% | 1699717-32-2 | 100mg | $1283.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611940 | BAY-545 >98% | 1699717-32-2 | 250mg | $2245.7 | 2021-12-16 | Buy |
| ChemScene | CS-0090874 | BAY-545 97.06% | 1699717-32-2 | 50mg | $2250 | 2021-12-16 | Buy |
BAY-545 Chemical Properties,Uses,Production
Uses
BAY-545 is a potent and selective A2B adenosine receptor antagonist, with an IC50 of 59 nM. BAY-545 also exhibits IC50s of 66, 400, 280 nM for human, mouse, rat A2B adenosine receptor in cells, respectively, and a Ki of 97 nM for human A2B adenosine receptor, with more selectivity over A1, A2A, and A3 adenosine receptor[1].
References
[1] H?rter M, et al. Novel non-xanthine antagonist of the A2B adenosine receptor: From HTS hit to lead structure. Eur J Med Chem. 2019 Feb 1;163:763-778. DOI:10.1016/j.ejmech.2018.11.045
BAY-545 Preparation Products And Raw materials
Raw materials
Preparation Products
BAY-545 Suppliers
Global( 49)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5221 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
BAY-545
BAY-545;BAY545;BAY 545;1699717-32-2
Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 3-ethyl-6-[(4-hydroxy-1-piperidinyl)carbonyl]-5-methyl-1-(3,3,3-trifluoropropyl)-
3-Ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
Inhibitor,BAY 545,BAY545,Adenosine Receptor,BAY-545,P1 receptor,inhibit
BAY-545, 10 mM in DMSO
1699717-32-2