MRS1177
- CAS No.
- 183721-13-3
- Chemical Name:
- MRS1177
- Synonyms
- MRS1177;MRS-1177,MRS1177;Benzamide, N-[9-chloro-2-(2-furanyl)[1,2,4]triazolo[1,5-c]quinazolin-5-yl]-
- CBNumber:
- CB24845023
- Molecular Formula:
- C20H12ClN5O2
- Molecular Weight:
- 389.79
- MDL Number:
- MFCD31807617
- MOL File:
- 183721-13-3.mol
- MSDS File:
- SDS
MRS1177 Chemical Properties, Uses, Production
Description
MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM.
MRS1177 (compound 2b) is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist[1]. The Ki value of MRS1177 (compound 55) with hA3AR is 0.3 nM[2].
Uses
MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM.
References
[1]. Tafi A, et al. Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem. 2006 Jul 13;49(14):4085-97. [2]. Cheong SL, et al. Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists. Bioorg Med Chem Lett. 2011 May 15;21(10):2898-905.
MRS1177 Preparation Products And Raw materials
Raw materials
Preparation Products
MRS1177 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| BOC Sciences | 65 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 56 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
