N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine
- CAS No.
- 339303-87-6
- Chemical Name:
- N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine
- Synonyms
- UCLA P130 2;GP130 receptor agonist-1;GP130 receptor agonist-1, 10 mM in DMSO;N-(4-Fluorophenyl)-4-phenyl-2-thiazolami;N-(4-Fluorophenyl)-4-phenylthiazol-2-amine;N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine;2-Thiazolamine, N-(4-fluorophenyl)-4-phenyl-;GP130 receptor agonist-1,neuroprotective,Inhibitor,penetrant,NMDA,inhibit,GP-130 receptor agonist-1,brain,Interleukin Related,GP130 receptor agonist1,GP130,GP130 receptor agonist 1
- CBNumber:
- CB24902807
- Molecular Formula:
- C15H11FN2S
- Molecular Weight:
- 270.32
- MDL Number:
- MFCD00784992
- MOL File:
- 339303-87-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 35551 | UCLA gp130 2 ≥98% | 339303-87-6 | 5mg | $97 | 2026-04-30 | Buy |
| Cayman Chemical | 35551 | UCLA gp130 2 ≥98% | 339303-87-6 | 10mg | $174 | 2026-04-30 | Buy |
| Cayman Chemical | 35551 | UCLA gp130 2 ≥98% | 339303-87-6 | 25mg | $412 | 2026-04-30 | Buy |
| Cayman Chemical | 35551 | UCLA gp130 2 ≥98% | 339303-87-6 | 50mg | $676 | 2026-04-30 | Buy |
| Biosynth | PNA30387 | N-(4-Fluorophenyl)-4-phenyl-1,3-thiazol-2-amine | 339303-87-6 | 25mg | $539.5 | 2026-06-04 | Buy |
N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine Chemical Properties, Uses, Production
Uses
N-(4-Fluorophenyl)-4-phenyl-1,3-thiazol-2-amine is a gp130 agonist. Protects against NMDA-induced toxicity in primary hippocampal neurons in vitro. Increases STAT3 phosphorylation in SH-SY5Y cells. Brain penetrant.
in vivo
For GP130 receptor agonist-1 (Compound 2), mice are dosed orally at 10 or 30 mg/kg, or injected subcutaneously (SQ) at 10 mg/kg, and euthanized after 1, 2, 4, 6, and 8 h post dose. At 2 h after SQ delivery at 10 mg/kg the brain Cmax is 161 ng/g while dosing at 30 mg/kg orally, results in the brain Cmax of 156 ng/g (0.57 μM). The brain to plasma ratio for 2 is ～4:1 for oral 30 mg/kg and ～7.5:1 for 10 mg/kg SQ injection[1].
storage
Store at +4°C
N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine Preparation Products And Raw materials
Raw materials
Preparation Products
N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9777 | 55 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shandong Jirun Biomedical Technology Co., Ltd. | 0539-0539-8613587 17661611089 | 2639273505@qq.com | China | 237 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 5000 | 58 |
View Latest Price from N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | GP130 receptor agonist-1
339303-87-6
|
$41.00-128.00 | 99.70% | 10g | TargetMol Chemicals Inc. |
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- GP130 receptor agonist-1
339303-87-6
- $41.00-128.00
- 99.70%
- TargetMol Chemicals Inc.
