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5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER

5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER structure

CAS No.: 14678-87-6

Chemical Name:: 5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER

Synonyms: AKOS BBS-00004494;BUTTPARK 19\09-71;SALOR-INT L251445-1EA;ETHYL 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE;5-amino-1-(4-chlorophenyl)pyrazole-4-carboxylic acid ethyl ester;5-amino-1-(4-chlorophenyl)-4-pyrazolecarboxylic acid ethyl ester;5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;1H-Pyrazole-4-carboxylic acid, 5-amino-1-(4-chlorophenyl)-, ethyl ester

CBNumber:: CB2491473

Molecular Formula:: C12H12ClN3O2

Molecular Weight:: 265.7

MDL Number:: MFCD00973905

MOL File:: 14678-87-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 00:38:00

Product description	Number	Pack Size	Price
ETHYL 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE Aldrich^CPR	L251445	1 unit	$32.7
ETHYL 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE AldrichCPR	L251445	250MG	$29.8
Ethyl 5-amino-1-(4-chlorophenyl)-pyrazole-4-carboxylate ≥98%(HPLC)	25073	1G	$89.13
Ethyl 5-amino-1-(4-chlorophenyl)-pyrazole-4-carboxylate ≥98%(HPLC)	25073	5G	$288.33
Ethyl 5-amino-1-(4-chlorophenyl)-pyrazole-4-carboxylate ≥98%(HPLC)	25073	25G	$1184.97

Request For Quotation

5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER Properties

storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	L251445	ETHYL 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE Aldrich^CPR	14678-87-6	1 unit	$32.7	2026-04-30	Buy
Sigma-Aldrich	L251445	ETHYL 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE AldrichCPR	14678-87-6	250MG	$29.8	2024-03-01	Buy
Chem-Impex	25073	Ethyl 5-amino-1-(4-chlorophenyl)-pyrazole-4-carboxylate ≥98%(HPLC)	14678-87-6	1G	$89.13	2026-05-19	Buy
Chem-Impex	25073	Ethyl 5-amino-1-(4-chlorophenyl)-pyrazole-4-carboxylate ≥98%(HPLC)	14678-87-6	5G	$288.33	2026-05-19	Buy
Chem-Impex	25073	Ethyl 5-amino-1-(4-chlorophenyl)-pyrazole-4-carboxylate ≥98%(HPLC)	14678-87-6	25G	$1184.97	2026-05-19	Buy

Product number	Packaging	Price	Buy
L251445	1 unit	$32.7	Buy
L251445	250MG	$29.8	Buy
25073	1G	$89.13	Buy
25073	5G	$288.33	Buy
25073	25G	$1184.97	Buy

5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Uses,Production

Synthesis

2-cyano-3-Methoxy-acrylic acid ethyl ester

68350-76-5

1073-69-4

5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER

14678-87-6

General procedure for the synthesis of ethyl 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carboxylate from ethyl 2-cyano-3-methoxyacrylate and p-chlorophenylhydrazine: 5 g (28 mmol) of p-chlorophenylhydrazine, 3.86 g (28 mmol) of potassium carbonate, and 4.7 g (28 mmol) of ethyl 2-cyano-3-methoxyacrylate were sequentially added to a 100 mL round bottomed flask. The reaction mixture was stirred under reflux conditions for 24 hours. Upon completion of the reaction, 150 mL of ethyl acetate was added to the reaction mixture, followed by washing twice with 100 mL of water. The organic layer was separated, dried with anhydrous magnesium sulfate, and the solvent was removed by distillation under reduced pressure to afford 6.88 g (26 mmol) of ethyl 5-amino-1-(4-chlorophenyl)-1H-pyrazole-4-carboxylate of the target compound in 92% yield. The product was analyzed by mass spectrometry (EI) showing a molecular ion peak of 266 (M++1). The nuclear magnetic resonance hydrogen spectrum (1H-NMR, CDCl3) data were as follows: δ 7.78 (1H, s), 7.52-7.47 (4H, m), 5.28 (2H, brs), 4.31 (2H, q, J=8Hz), 1.37 (3H, t, J=8Hz).

References

[1] Patent: WO2005/40127, 2005, A1. Location in patent: Page/Page column 39

5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

2-cyano-3-Methoxy-acrylic acid ethyl ester 4-Chlorophenylhydrazine

Preparation Products

5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER Suppliers

Global( 47)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14098	59
Nanjing YaoCheng Pharmaceutical Co., Ltd.	025-57043319 15261831516	307514552@qq.com	China	298	50
Shanghai YuanYe Biotechnology Co., Ltd.	13636370518	shyysw007@163.com	China	89667	60
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9696	58
Aikon International Limited	025-58859352 15955137747	sales01@aikonchem.com	China	16021	58
Nanjing xiangrui technology co. LTD	021-021-00000000 15715199582	njrich168@163.com	China	494	58
Energy Chemical	400-0056266	marketing1@energy-chemical.com	China	44926	58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.	13611835272 13611835272	mmwang@sunwaypharm.com	China	44091	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
Amadis Chemical Company Limited	58
Adamas Reagent, Ltd.	59
Nanjing YaoCheng Pharmaceutical Co., Ltd.	50
Shanghai YuanYe Biotechnology Co., Ltd.	60
Shanghai Chaolan Chemical Technology Center	58
Aikon International Limited	58
Nanjing xiangrui technology co. LTD	58
Energy Chemical	58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.	58

5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER Spectrum

5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER(14678-87-6)¹HNMR

14678-87-6(5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER)Related Search:

5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ethyl 5-amino-1-(4-chlorophenyl)-3-cyclobutyl-1H-pyrazole-4-carboxylate 5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER ethyl 5-amino-1-(2,4-dichlorophenyl)pyrazole-4-carboxylate ETHYL 5-AMINO-1-(3,4-DICHLOROPHENYL)-PYRAZOLE-4-CARBOXYLATE

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ETHYL 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE BUTTPARK 19\09-71 AKOS BBS-00004494 5-AMINO-1-(4-CHLORO-PHENYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 5-amino-1-(4-chlorophenyl)-4-pyrazolecarboxylic acid ethyl ester 5-amino-1-(4-chlorophenyl)pyrazole-4-carboxylic acid ethyl ester SALOR-INT L251445-1EA 1H-Pyrazole-4-carboxylic acid, 5-amino-1-(4-chlorophenyl)-, ethyl ester 14678-87-6